Articles:
9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-aminohydropurin-6-one
Notes:
a purine nucleoside that has guanine linked by its n9 nitrogen to the c1 carbon of ribose. it is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (from dorland, 28th ed) Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a beta-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate). (Wikipedia); The nucleoside guanosine exert important neuroprotective and neuromodulator roles in the central nervous system, which may be related to inhibition of the glutamatergic neurotransmission activity. Guanosine is the specific extracellular guanine-based purines effector and indicate that its conversion occurs not only in the central nervous system but also peripherally. (PMID: 16325434); Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 118-00-3 Guanosine ≥98% by HPLC
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GE8690 Guanosine
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 07-61800 GUANOSINE HYDRATE
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| CAS Number: | 118-00-3 |  3D/inchi
|
| Other(deleted CASRN): | 484-80-0 | |
| ECHA EINECS - REACH Pre-Reg: | 204-227-8 | |
| FDA UNII: | 12133JR80S | |
| Nikkaji Web: | J10.076E | |
| Beilstein Number: | 625911 | |
| MDL: | MFCD00010182 | |
| XlogP3: | -2.70 (est) | |
| Molecular Weight: | 283.24461000 | |
| Formula: | C10 H13 N5 O5 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: opacifying agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 239.00 °C. @ 760.00 mm Hg |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | -2.331 (est) |
| Soluble in: | |
| water, 3.153e+004 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
opacifying agents skin conditioning |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Guanosine 98% |
| BOC Sciences |
| For experimental / research use only. |
| Guanosine ≥98% by HPLC |
| Carbosynth |
| For experimental / research use only. |
| Guanosine |
| Changzhou Longo Chemical |
| Guanosine |
| George Uhe Company |
| Guanosine |
| Glentham Life Sciences |
| Guanosine |
| Penta International |
| GUANOSINE HYDRATE |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Guanosine ≥98% |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LD50 500 mg/kg National Technical Information Service. Vol. AD277-689 intravenous-mouse LD50 180 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03206 | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | opacifying agents | ||
| Recommendation for guanosine hydrate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for guanosine hydrate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 118-00-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6802 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one | |
| Chemidplus: | 0000085303 |
| RTECS: | MF8750000 for cas# 118-00-3 |
References:
| 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 118-00-3 |
| Pubchem (cid): | 6802 |
| Pubchem (sid): | 134972817 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C00387 |
| HMDB (The Human Metabolome Database): | HMDB00133 |
| FooDB: | FDB003632 |
| YMDB (Yeast Metabolome Database): | YMDB00509 |
| Export Tariff Code: | 2934.90.5000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| biological additives |
Occurrence (nature, food, other): note
| beet root Search Trop Picture | |
| coffee bean Search Trop Picture | |
| garlic bulb Search Trop Picture | |
| garlic tuber Search Trop Picture | |
| hazelnut pollen Search Trop Picture | |
| wheat petiole Search Trop Picture |
Synonyms:
| 2- | amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one |
| 2- | amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one |
| 2- | amino-inosine |
| 2- | aminoinosine |
| 9-[(4S,2R,3R,5R)-3,4- | dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-aminohydropurin-6-one |
| 9-((2R,3R,4S,5R)-3,4- | dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-imino-2,3-dihydro-1H-purin-6(9H)-one |
| 9-((2R,3R,4S,5R)-3,4- | dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-imino-1,2,3,9-tetrahydro-purin-6-one |
| guanine riboside | |
| inosine, 2-amino- | |
| nucleoside Q | |
| vernine |