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Category: buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless crystals (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 79.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 265.57 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 264.00 °F. TCC ( 128.70 °C. ) (est)
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| logP (o/w): | -1.204 (est) |
| Soluble in: |
| | alcohol | | | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor Type: buttery |
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Odor Description: at 100.00 %. | odorless very mild buttery Luebke, William tgsc, (1996) |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| Beijing Lys Chemicals |
| Glycolic acid
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| BOC Sciences |
| For experimental / research use only. |
| Hydroxyacetic Acid ultra pure crystals
Odor: characteristic Use: Constituent of sugar cane juice. |
| Charkit Chemical |
| GLYCOLIC ACID 70%
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| Connect Chemicals |
| Glycolic acid 70% (cosmetic grade)
Odor: characteristic Use: Glycolic Acid 70% (cosmetic grade) is the smallest molecule of the Alpha Hydroxy Acid. Due to its small size it is able to penetrate the skin, getting into the pores to clear out debris and unclog the pores. This stimulates new growth of skin and removal of old, dead, dull skin.
Glycolic Acid 70% (cosmetic grade) is mainly used to improve the appearance and texture of the skin through chemical peel process. Once applied to the skin it breaks down the lipids that hold the dead skin cells on the surface, speeding their removal, resulting in an improved appearance with fewer spots, refined pores, and a more even skin tone that is more radiant. |
| Covalent Chemical |
| Glycolic Acid
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| ECSA Chemicals |
| GLYCOLIC ACID 70%
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| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| Glentham Life Sciences |
| Glycolic acid
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| Penta International |
| GLYCOLIC ACID 70% TECHNICAL GRADE
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| Penta International |
| GLYCOLIC ACID 99% POWDER
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| Sigma-Aldrich |
| For experimental / research use only. |
| Glycolic Acid ReagentPlus®, 99%
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| Silver Fern Chemical |
| Glycolic Acid
Odor: characteristic Use: Glycolic acid is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent. It is also used in adhesives and plastics. Glycolic acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss. |
| WholeChem |
| Glycolic acid
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Safety Information:
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-cat LD50 1000 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 656, 1986.
oral-guinea pig LD50 1920 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
GASTROINTESTINAL: OTHER CHANGES Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
oral-rat LD50 1950 mg/kg GASTROINTESTINAL: OTHER CHANGES
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
KIDNEY, URETER, AND BLADDER: OTHER CHANGES Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-rat LC50 7100 ug/m3/4H SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Inhalation Toxicology. Vol. 9, Pg. 435, 1997.
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Safety in Use Information:
| Category: | buffering agents |
| Recommendation for glycolic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for glycolic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| European Food Safety Authority (EFSA) reference(s): |
18th list of substances for food contact materials - Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food View page or View pdf |
Scientific Opinion on the safety evaluation of the substance glycolic acid for use in food contact materials View page or View pdf |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| NIOSH International Chemical Safety Cards: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 79-14-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 757 |
| National Institute of Allergy and Infectious Diseases: | Data |
| SCCNFP: | opinion |
| WGK Germany: | 1 |
| | 2-hydroxyacetic acid |
| Chemidplus: | 0000079141 |
| RTECS: | 79-14-1 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00160 |
| HMDB (The Human Metabolome Database): | HMDB00115 |
| FooDB: | FDB003298 |
| YMDB (Yeast Metabolome Database): | YMDB00807 |
| Export Tariff Code: | 2918.19.9000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •grades: technical, 70% soln; pure crystals. avail commercially as 70% soln.
•available commercially as either a 57% (hoechst) or a 70% (du pont) aqueous solution
•clorox patch: active ingredient 1.5% glycolic acid.
•x-men: active ingredients 3.070% glycolic acid, 0.180% alkyl dimethyl benzyl ammonium chloride (50%c14, 40%c12, 10%c16), 0.081% didecyl dimethyl ammonium chloride, 0.135% octyl decyl dimethyl ammonium chloride & 0.054% dioctyl dimethyl ammonium chloride.
•show: active ingredient 11.185% glycolic acid.
•dupont glyclean am: active ingredient 70% glycolic acid.
•dupont bowl cleaner: active ingredient 9.5% glycolic acid.
•dupont kleanit: active ingredient 5% glycolic acid.
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetic acid, 2-hydroxy- | | | acetic acid, hydroxy- | | | glycol acid | | | glycolicacid | | | glycollic acid | | | GOA | | 2- | hydroxyacetic acid | | a- | hydroxyacetic acid | | 2- | hydroxyethanoic acid |
Articles:
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