Articles:
| None found yet. Try the PubMed Search. |
ethyleneglycol
Notes:
a colorless, odorless, viscous dihydroxy alcohol. it has a sweet taste, but is poisonous if ingested. ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the united states. it is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 107-21-1 Ethylene glycol 99%
-
-
ECSA Chemicals Human Chemistry ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide. ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators. Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials. Email: Info Email: Sales Email: Trading Email: Maintenance Email: Energy Voice: +41 91 695 88 00 Fax: +41 91 695 88 01 Linkedin Youtube RSS Feed ECSA Trade ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY Products List: View Product(s): MP-010603 ETHYLENE GLYCOL MP-030241 ETHYLENE GLYCOL 30% RE-346501 ETHYLENE GLYCOL RE-PURE, ML 1000
-
-
Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GK7641 Ethylene glycol
-
-
Lluch Essence S.L. A family company dedicated to sales and distribution Flexibility, availability, price and quality. Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world. Email: Info Voice: 34 93 379 38 49 Fax: 34 93 370 65 04 Linkedin Product(s): ETHYLENE GLYCOL
-
| CAS Number: | 107-21-1 |  3D/inchi
|
| Other(deleted CASRN): | 37221-95-7 | |
| ECHA EINECS - REACH Pre-Reg: | 203-473-3 | |
| FDA UNII: | FC72KVT52F | |
| Nikkaji Web: | J4.061D | |
| Beilstein Number: | 505945 | |
| MDL: | MFCD00002885 | |
| XlogP3: | -1.40 (est) | |
| Molecular Weight: | 62.06822000 | |
| Formula: | C2 H6 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: humectants, solvents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Contact Materials: | ethyleneglycol |
| FDA Mainterm (IAUFC): | 107-21-1 ; ETHYLENE GLYCOL |
Physical Properties:
| Appearance: | colorless to pale yellow clear oily liquid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.11300 @ 25.00 °C. |
| Melting Point: | -12.00 to -11.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 197.00 to 198.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 121.00 to 122.00 °C. @ 50.00 mm Hg |
| Vapor Pressure: | 0.096000 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w): | -1.688 (est) |
| Soluble in: | |
| water, 1e+006 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
humectants solvents viscosity controlling agents |
Suppliers:
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-cat LD50 1650 mg/kg KIDNEY, URETER, AND BLADDER: OTHER CHANGES Recueil de Medecine Veterinaire. Vol. 154, Pg. 137, 1978. oral-child TDLo 5500 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: GENERAL ANESTHETIC KIDNEY, URETER, AND BLADDER: OTHER CHANGES Postgraduate Medical Journal. Vol. 52, Pg. 598, 1976. oral-dog LD50 5500 mg/kg KIDNEY, URETER, AND BLADDER: OTHER CHANGES Recueil de Medecine Veterinaire. Vol. 154, Pg. 137, 1978. oral-guinea pig LD50 6610 mg/kg GASTROINTESTINAL: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941. unreported-guinea pig LD50 11150 mg/kg BEHAVIORAL: EXCITEMENT BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. oral-human LDLo 398 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: HEADACHE LIVER: OTHER CHANGES Sudebno-Meditsinskaya Ekspertiza. Forensic Medical Examination. Vol. 26(2), Pg. 48, 1983. oral-human LDLo 786 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: COMA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 373, 1976. unreported-man LDLo 1637 mg/kg "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. oral-man TDLo 1195 mg/kg KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE Annals of Emergency Medicine. Vol. 20, Pg. 208, 1991. oral-man TDLo 15000 mg/kg KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE Annals of Emergency Medicine. Vol. 20, Pg. 208, 1991. oral-man TDLo 16000 mg/kg KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED BEHAVIORAL: COMA Human & Experimental Toxicology. Vol. 9, Pg. 317, 1990. oral-man TDLo 24000 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Toxicology, Clinical Toxicology. Vol. 38, Pg. 445, 2000. intraperitoneal-mouse LD50 5614 mg/kg KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI BLOOD: CHANGES IN SPLEEN LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947. intravenous-mouse LD50 3000 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939. oral-mouse LD50 5500 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(3), Pg. 31, 1967. unreported-mouse LD50 8050 mg/kg BEHAVIORAL: EXCITEMENT GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. unreported-rabbit LD50 5017 mg/kg BEHAVIORAL: EXCITEMENT GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. intramuscular-rabbit LDLo 5500 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 41, Pg. 387, 1931. intraperitoneal-rabbit LDLo 1000 mg/kg Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 502, 1966. intravenous-rabbit LDLo 5000 mg/kg BEHAVIORAL: TREMOR BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 41, Pg. 387, 1931. intraperitoneal-rat LD50 5010 mg/kg Kriobiologiya i Kriomeditsina. Cryobiology and Cryomedicine. Vol. 9, Pg. 36, 1981. intravenous-rat LD50 3260 mg/kg Kriobiologiya i Kriomeditsina. Cryobiology and Cryomedicine. Vol. 9, Pg. 36, 1981. oral-rat LD50 4700 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(6), Pg. 28, 1982. unreported-rat LD50 13000 mg/kg BEHAVIORAL: EXCITEMENT GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. intramuscular-rat LDLo 3300 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 41, Pg. 387, 1931. | |
| Dermal Toxicity: | |
|
subcutaneous-cat LDLo 2000 mg/kg BEHAVIORAL: MUSCLE WEAKNESS BLOOD: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933. subcutaneous-guinea pig LDLo 5000 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 51, Pg. 398, 1935. subcutaneous-mouse LDLo 2700 mg/kg British Journal of Industrial Medicine. Vol. 1, Pg. 207, 1944. skin-rabbit LD50 9530 uL/kg "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969. subcutaneous-rat LD50 2800 mg/kg Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 49, 1974. | |
| Inhalation Toxicity: | |
|
inhalation-human TCLo 10000 mg/m3 LUNGS, THORAX, OR RESPIRATION: COUGH SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933. inhalation-mouse LC > 200 mg/m3/2H Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981. inhalation-rat LC > 200 mg/m3/4H Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981. | |
Safety in Use Information:
| Category: | humectants, solvents | ||
| Recommendation for ethylene glycol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for ethylene glycol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Safety of the proposed amendment of the specifications for the food additive polyvinyl alcohol-polyethylene glycol-graft-co-polymer (E 1209) View page or View pdf | |
| EPI System: | View |
| EPA-Iris: | IRIS |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| NIOSH International Chemical Safety Cards: | search |
| NIOSH Pocket Guide: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 107-21-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 174 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| ethane-1,2-diol | |
| Chemidplus: | 0000107211 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | 107-21-1 |
References:
| ethane-1,2-diol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 107-21-1 |
| Pubchem (cid): | 174 |
| Pubchem (sid): | 134972261 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C01380 |
| HMDB (The Human Metabolome Database): | Search |
| YMDB (Yeast Metabolome Database): | YMDB01564 |
| Export Tariff Code: | 2905.31.0000 |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •emulsifiable glycol ointment base (base g): polyethylene glycol 400 monostearate- 26 g, polyethylene glycol 400- 37 g, polyethylene glycol 4000- 37 g. •carbowax polyethylene glycol bases- base a: polyethylene glycol 1000- 96%, polyethylene glycol 4000- 4%; base b: polyethylene glycol 1000- 75%, polyethylene glycol 4000- 25%; base c: polyethylene glycol 1540- 70%, polyethylene glycol 6000- 50%. suppository preparation, from table •carbowax polyethylene glycol bases- base d: polyethylene glycol 6000- 50%, polyethylene glycol 1540- 30%, water and medication- 20%. suppository preparation, from table •ointment, with cetyl alcohol: polyethylene glycol 4000- 47.5 g, polyethylene glycol 400- 47.5 g, cetyl alcohol, to make 100 g; polyethylene glycol ointment, with sorbitan monopalmitate: polyethylene glycol 4000- 50 g, polyethylene glycol 400- 40 g, sorbitan monopalmitate- 1 g, purified water to make 100 g. •polyethylene glycol 300 nf; polyethylene glycol 400 usp; polyethylene glycol 1500; polyethylene glycol 1540 nf; polyethylene glycol 4000 usp; polyethylene glycol ointment usp: polyethylene glycol 4000- 40 g, polyethylene glycol, to make 100 g. •official ointment base is mixture of polyethylene glycol 4000 and 400. this base is water-soluble and non-staining. when a firmer preparation is desired not more than 10% of polyethylene glycol 400 may be replaced by an equal amount of polyethylene glycol 4000. •available in a broad range of molecular weight grades, i.e., as low as 100,000 to over 5x10+6 | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| solvents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 1,2- | dihydroxyethane |
| 1,2- | ethandiol |
| ethane-1,2-diol | |
| 1,2- | ethanediol |
| ethylene alcohol | |
| mono | ethylene glycol |
| ethyleneglycol |