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Category: sweeteners, flavor enhancers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 98.00 to 100.00 %
|
| Food Chemicals Codex Listed: | Yes |
| Boiling Point: | 808.00 to 810.00 °C. @ 760.00 mm Hg
|
| Flash Point: | 829.00 °F. TCC ( 442.78 °C. )
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| Soluble in: |
| | alcohol, slightly | | | water | | | water, 58.66 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| a,a-D-Trehalose dihydrate endotoxin free
|
| Carbosynth |
| For experimental / research use only. |
| a,a-D-Trehalose dihydrate
|
| Charkit Chemical |
| TREHALOSE DIHYDRATE
|
| ECSA Chemicals |
| TREHALOSE
|
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| EMD Millipore |
| For experimental / research use only. |
| Trehalose, Dihydrate
|
| ExtraSynthese |
| For experimental / research use only. |
| Trehalose
|
| Glentham Life Sciences |
| D-(+)-Trehalose dihydrate, Ph. Eur. grade
|
| Glentham Life Sciences |
| D-(+)-Trehalose dihydrate
|
| Indis NV |
| For experimental / research use only. |
| Trehalose Dihydrate
|
| Jiangyin Healthway |
| Trehalose
|
| New functional food ingredients |
| Jiangyin Healthway |
| Trehalose
|
| Matrix Scientific |
| For experimental / research use only. |
| D-(+)-Trehalose dihydrate, 95+%
|
| Penta International |
| D-(+)-TREHALOSE DIHYDRATE
|
| Pfanstiehl, Inc |
| a,a – Trehalose Dihydrate, High Purity (Low Endotoxin), USP/NF, EP, JP, ChP
Odor: characteristic Use: Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an a, a–1,1 bond. Pfanstiehl Brand, High Purity Low Endotoxin Trehalose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a key component in cryopreservation/freeze media to stabilize cell membranes and improve the recovery and robustness of cells used for bioproduction and cell therapy. |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Trehalose Dihydrate 98%
|
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| D-(+)-Trehalose dihydrate from Saccharomyces cerevisiae, ≥99%
|
| Spec-Chem Industry |
| SpecKare TM TRHL(Trehalose)
|
| TCI AMERICA |
| For experimental / research use only. |
| D-(+)-Trehalose Dihydrate >98.0%(GC)
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | sweeteners, flavor enhancers |
| Recommendation for dextro-trehalose dihydrate usage levels up to: | | | not for fragrance use.
|
| |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 24 |
| Click here to view publication 24 |
| | average usual ppm | average maximum ppm |
| baked goods: | 20000.00000 | 50000.00000 |
| beverages(nonalcoholic): | 20000.00000 | 35000.00000 |
| beverages(alcoholic): | 1000.00000 | 10000.00000 |
| breakfast cereal: | 15000.00000 | 30000.00000 |
| cheese: | 3000.00000 | 50000.00000 |
| chewing gum: | 20000.00000 | 35000.00000 |
| condiments / relishes: | 20000.00000 | 50000.00000 |
| confectionery froastings: | 20000.00000 | 50000.00000 |
| egg products: | 15000.00000 | 40000.00000 |
| fats / oils: | 15000.00000 | 40000.00000 |
| fish products: | 15000.00000 | 50000.00000 |
| frozen dairy: | 15000.00000 | 50000.00000 |
| fruit ices: | 10000.00000 | 50000.00000 |
| gelatins / puddings: | 50000.00000 | 50000.00000 |
| granulated sugar: | - | - |
| gravies: | 20000.00000 | 50000.00000 |
| hard candy: | 50000.00000 | 50000.00000 |
| imitation dairy: | 20000.00000 | 50000.00000 |
| instant coffee / tea: | 10000.00000 | 30000.00000 |
| jams / jellies: | 50000.00000 | 50000.00000 |
| meat products: | 15000.00000 | 50000.00000 |
| milk products: | 20000.00000 | 50000.00000 |
| nut products: | 20000.00000 | 50000.00000 |
| other grains: | 15000.00000 | 30000.00000 |
| poultry: | 15000.00000 | 50000.00000 |
| processed fruits: | 10000.00000 | 30000.00000 |
| processed vegetables: | 35000.00000 | 50000.00000 |
| reconstituted vegetables: | 15000.00000 | 30000.00000 |
| seasonings / flavors: | 20000.00000 | 50000.00000 |
| snack foods: | 20000.00000 | 50000.00000 |
| soft candy: | 50000.00000 | 50000.00000 |
| soups: | 20000.00000 | 50000.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | 50000.00000 | 50000.00000 |
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 181978 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | 2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate |
| Chemidplus: | 0006138234 |
| RTECS: | LZ5776547 for cas# 6138-23-4 |
References:
| | 2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 181978 |
| Pubchem (sid): | 135158900 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| a-D- | glucopyranoside, a-D-glucopyranosyl, hydrate (1:2) | | 1-O-alpha-D- | glucopyranosyl-alpha-dextro-glucopyranoside | | 1-O-alpha-dextro- | glucopyranosyl-alpha-dextro-glucopyranoside | | 2-( | hydroxymethyl)-6-(3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxane-3,4,5-triol dihydrate | | 2-( | hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate | | D- | trehalose dihydrate | | D-(+)- | trehalose dihydrate | | | trehalose, dihydrate |
Articles:
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