Articles:
ethanaminium, 1-carboxy-2-hydroxy-, inner salt, (1R)-
Notes:
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines, pyrimidines, and other amino acids.
As a constituent (residue) of proteins, its side chain can undergo O-linked glycosylation. This might be important in explaining some of the devastating consequences of diabetes. It is one of three amino acid residues that are commonly phosphorylated by kinases during cell signalling in eukaryotes. Phosphorylated serine residues are often referred to as phosphoserine. Serine proteases are a common type of protease.
Serine (IPA [sejin]), organic compound, one of the 20 amino acids commonly found in animal proteins. Only the L-stereoisomer appears in mammalian protein. It is not essential to the human diet, since it can be synthesized in the body from other metabolites, including glycine. Serine was first obtained from silk protein, a particularly rich source, in 1865. Its name is derived from the Latin for silk, sericum. Serine's structure was established in 1902. [HMDB]
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GM2756 D-Serine SDS
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 19-14200 D-SERINE
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): S0033 D-Serine >98.5%(T)
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| CAS Number: | 312-84-5 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 206-229-4 | |
| FDA UNII: | 1K77H2Z9B1 | |
| Nikkaji Web: | J1.196G | |
| Beilstein Number: | 1721403 | |
| MDL: | MFCD00004269 | |
| XlogP3: | -3.10 (est) | |
| Molecular Weight: | 105.09339000 | |
| Formula: | C3 H7 N O3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 229.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 394.82 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 379.00 °F. TCC ( 192.60 °C. ) (est) |
| logP (o/w): | -1.490 (est) |
| Soluble in: | |
| water, 3.64E+05 mg/L @ 20 °C (exp) | |
| water, 4.02e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Cycloserine Impurity 1 > 95%
Odor: characteristic Use: D-Serine is a proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. It is a inhibitor of serine palmitoyltransferase. It is also a neuromodulator. |
| Changzhou Longo Chemical |
| D-Serine |
| Glentham Life Sciences |
| D-Serine |
| Penta International |
| D-SERINE |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| D-Serine ≥98% (TLC) |
| TCI AMERICA |
| For experimental / research use only. |
| D-Serine >98.5%(T) |
| Universal Preserv-A-Chem Inc. |
| D-SERINE
Odor: characteristic Use: D-Serine is an amino acid found in the brain. Derived from Glycine, d-serine is a neuromodulator, meaning it regulates the activities of neurons. |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | information only not used for fragrances or flavors | ||
| Recommendation for dextro-serine usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dextro-serine flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 312-84-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 71077 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| (2R)-2-amino-3-hydroxypropanoic acid | |
| Chemidplus: | 0000312845 |
References:
| (2R)-2-amino-3-hydroxypropanoic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 71077 |
| Pubchem (sid): | 135028206 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C00740 |
| HMDB (The Human Metabolome Database): | HMDB03406 |
| FooDB: | FDB023164 |
| YMDB (Yeast Metabolome Database): | YMDB00284 |
| Export Tariff Code: | 2922.50.5000 |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| antistatic agents | ||
| humectants |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| (R)-2- | amino-3-hydroxy-propionic acid |
| (2R)-2- | amino-3-hydroxypropanoic acid |
| (R)-2- | amino-3-hydroxypropanoic acid |
| D-2- | amino-3-hydroxypropanoic acid |
| (R)-2- | amino-3-hydroxypropionic acid |
| D-2- | amino-3-hydroxypropionic acid |
| R(-)-2- | amino-3-hydroxypropionic acid |
| ethanaminium, 1-carboxy-2-hydroxy-, inner salt, (1R)- | |
| D- | serin |
| (R)- | serine |
| D- | serine |
| D-(-)- | serine |
| serine D- | |
| serine, D- |