Articles:
beta-D-anhydroglucuronate
Notes:
D-glucurono-6,3-lactone participates in ascorbate and aldarate metabolism. D-glucurono-6,3-lactone is produced by the reaction between D-glucaric acid and the enzyme, aldehyde dehydrogenase (NAD+) [EC: 1.2.1.3]. [HMDB]
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 32449-92-6 D-Glucurono-3,6-lactone
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Charkit Chemical Corporation The Specialty Chemical Specialists Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you. about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals. Email: Sales Voice: 203-299-3220 Fax: 203-299-1355 Facebook Twitter Linkedin Latest News Events Blog Products List: View Product(s): GLUCURONOLACTONE, D-
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): G0055 D-Glucurono-6,3-lactone >99.0%(T)
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| CAS Number: | 32449-92-6 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 251-053-3 | |
| FDA UNII: | XE4Y3016M9 | |
| Nikkaji Web: | J3.805I | |
| Beilstein Number: | 0083595 | |
| MDL: | MFCD00135622 | |
| XlogP3-AA: | -1.80 (est) | |
| Molecular Weight: | 176.12496000 | |
| Formula: | C6 H8 O6 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: special dietary and nutritional additives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 98.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 174.00 to 178.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 403.00 to 404.00 °C. @ 760.00 mm Hg |
| Flash Point: | 346.00 °F. TCC ( 174.44 °C. ) |
| logP (o/w): | -3.457 (est) |
| Soluble in: | |
| alcohol | |
| water, 257000 mg/L @ 21C (exp) | |
Organoleptic Properties:
| Odor Type: mentholic | |
| Odor Strength: | low |
| mentholic | |
| Odor Description: at 100.00 %. | very mild mentholic |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
skin conditioning |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| D-Glucurono-3,6-lactone |
| Carbosynth |
| For experimental / research use only. |
| D-Glucuronolactone |
| Charkit Chemical |
| GLUCURONOLACTONE, D- |
| EMD Millipore |
| For experimental / research use only. |
| D-(+)-Glucurolactone |
| Foodchem International |
| D-Glucurolactone |
| Prinova |
| D-Glucurolactone 99% min. CP |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| D-Glucurono-3,6-lactone ≥98% |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| D-(+)-Glucuronic acid gamma-lactone ≥99% |
| TCI AMERICA |
| For experimental / research use only. |
| D-Glucurono-6,3-lactone >99.0%(T) |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
|
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 10700 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. intravenous-rat LD50 3200 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. intravenous-rabbit LD50 940 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. oral-mouse LD50 > 20000 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. intravenous-mouse LD50 4568 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. intraperitoneal-mouse LD50 5797 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. intravenous-dog LD50 940 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. | |
| Dermal Toxicity: | |
|
subcutaneous-rat LD50 4700 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. subcutaneous-rabbit LD50 4700 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. subcutaneous-mouse LD50 8210 ul/kg Drugs in Japan Vol. 6, Pg. 225, 1982. subcutaneous-cat LD50 4700 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. subcutaneous-dog LD50 4700 mg/kg Drugs in Japan Vol. 6, Pg. 225, 1982. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | special dietary and nutritional additives | ||
| Recommendation for dextro-glucurolactone usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dextro-glucurolactone flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| The use of taurine and D-glucurono-gamma-lactone as constituents of the so-called “energy” drinks View page or View pdf | |
| Gathering consumption data on specific consumer groups of energy drinks View page or View pdf | |
| Scientific Opinion on the safety of caffeine View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 32449-92-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 92283 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| (2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde | |
| Chemidplus: | 0032449926 |
| RTECS: | LZ8930000 for cas# 32449-92-6 |
References:
| (2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 32449-92-6 |
| Pubchem (cid): | 92283 |
| Pubchem (sid): | 135048564 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C02670 |
| HMDB (The Human Metabolome Database): | HMDB06355 |
| FooDB: | FDB023903 |
| Export Tariff Code: | 2932.29.5050 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| skin conditioning |
Occurrence (nature, food, other): note
| found in nature |
Synonyms:
| beta-D- | anhydroglucuronate |
| beta-dextro- | anhydroglucuronate |
| dicurone | |
| (2R)-2-[(2S,3R,4S)-3,4- | dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde |
| (2R)-[(2S,3R,4S)-3,4- | dihydroxy-5-oxotetrahydrofuran-2-yl](hydroxy)acetaldehyde |
| glucofuranurono-6,3-lactone | |
| D- | glucurolactone |
| D- | glucuronic acid lactone |
| D- | glucurono-3,6-lactone |
| D- | glucurono-6,3-lactone |
| dextro- | glucurono-6,3-lactone |
| D- | glucurono-gamma-lactone |
| dextro- | glucurono-gamma-lactone |
| D- | glucuronolactone |