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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.86000 to 0.86300 @ 20.00 °C.
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| Pounds per Gallon - (est).: | 7.164 to 7.189
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| Refractive Index: | 1.44800 to 1.45100 @ 20.00 °C.
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| Melting Point: | 82.70 °C. @ 760.00 mm Hg
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| Boiling Point: | 108.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 24.187000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 63.00 °F. TCC ( 17.22 °C. )
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| logP (o/w): | 0.973 (est) |
| Soluble in: |
| | water, 1.383e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-rat LDLo 100 mg/kg Biochemical Pharmacology. Vol. 5, Pg. 108, 1960.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for cyclopentyl amine usage levels up to: | | | not for fragrance use.
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| Recommendation for cyclopentyl amine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | aminocyclopentane | | | cyclopentanamine | | | cyclopentylamine |
Articles:
| PubMed: | Discovery of a cyclopentylamine as an orally active dual NK1 receptor antagonist-serotonin reuptake transporter inhibitor. |
| PubMed: | Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists. |
| PubMed: | A new class of antitumor trans-amine-amidine-Pt(II) cationic complexes: influence of chemical structure and solvent on in vitro and in vivo tumor cell proliferation. |
| PubMed: | Inhibition of Lux quorum-sensing system by synthetic N-acyl-L-homoserine lactone analogous. |
| PubMed: | Nucleophilic reaction of cyclopentylamine on phthalimide derivatives: synthesis and antinociceptive activity of products. |
| PubMed: | Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists. |
| PubMed: | Carbocyclic ribosylamines: synthesis of 5-substituted carbocyclic beta-ribofuranosylamines. |
| PubMed: | Zeolite synthesis using degradable structure-directing agents and pore-filling agents. |
| PubMed: | Purification and characterization of a novel cyclohexylamine oxidase from the cyclohexylamine-degrading Brevibacterium oxydans IH-35A. |
| PubMed: | Amino substituted derivatives of 5'-amino-5'-deoxy-5'-noraristeromycin. |
| PubMed: | Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines. |
| PubMed: | Synthesis of carbocyclic phosphononucleosides. |
| PubMed: | Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C. |
| PubMed: | [The new antitumor drug cycloplatam: cytotoxicity and DNA interstrand cross-linking]. |
| PubMed: | Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally reconstituted influenza virus M2 proton channel protein. |
| PubMed: | Synthesis and Crystal Structures of Two Novel Anionic Aluminophosphates: A One-Dimensional Chain, UT-7 ([Al(3)P(5)O(20)H](5-)[C(7)H(13)NH(3)(+)](5)), and a Layer Containing Two Cyclic Amines, UT-8 ([Al(3)P(4)O(16)](3-)[C(4)H(7)NH(3)(+)](2)[C(5)H(10)NH(2)(+)]). |
| PubMed: | [Effect of anti-tumor agents cisplatin and cycloplatam on membrane protein kinase C activity in murine T-lymphocytes]. |
| PubMed: | Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo. |
| PubMed: | [Synthesis of tert-butylcyclopentane-fused 1,3-oxazines and 1,3-thiazines]. |
| PubMed: | Synthesis, characterization, and antitumor activity of amine platinum(II) and (IV) tellurate complexes. |
| PubMed: | Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin. |
| PubMed: | Synthesis and antitumor activity of ammine/amine platinum(II) and (IV) complexes. |
| PubMed: | Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites. |
| PubMed: | Preclinical antitumor activity of orally administered platinum (IV) complexes. |
| PubMed: | Influenza virus M2 protein: a molecular modelling study of the ion channel. |
| PubMed: | Antiproliferative effect of complexes of platinum (II) with plasmanyl-(N-acyl)-ethanolamine, an inhibitor of protein kinase C. |
| PubMed: | Effect of the amine non-leaving group on the structure and stability of DNA complexes with cis-[Pt(R-NH2)2(NO3)2]. |
| PubMed: | Modulation by polyamines of DNA-dependent DNA polymerase activity from human serum. |
| PubMed: | Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides. |
| PubMed: | Structures of cis-amminedichloro(cyclopentylamine)platinum 0.25-hydrate and potassium trichloro(cyclopentylamine)platinate 0.5-hydrate. |
| PubMed: | Incorporation of cis-dichlorobiscyclopentylamineplatinum (II) into liposomes enhances its uptake by ADJ/PC6A tumour cells: comparative effects of the free and liposome-incorporated drug on the cyclic 3'-5' nucleotide phosphodiesterase activity. |
| PubMed: | Oxidative deamination of alicyclic primary amines by liver microsomes from rats and rabbits. |
| PubMed: | Carbocyclic glycinamide ribonucleotide is a substrate for glycinamide ribonucleotide transformylase. |
| PubMed: | Cytostatic and antitumour properties of a new series of Pt (II) complexes with cyclopentylamine. |
| PubMed: | Enantioselective synthesis of new analogues of neplanocin A. |
| PubMed: | Synthesis and peripheral cardiovascular action of cis- and trans-2-(3,4-dimethoxybenzyl)cyclopentylamine hydrochlorides. |
| PubMed: | Growth in vivo of l5178y-r murine leukaemic cells treated in vitro with cis-dichloro bis-(cyclopentylamine) platinum II. |
| PubMed: | Isobologram analysis of the combined effects of anti-tumour platinum complexes and ionizing radiation on mammalian cells. |
| PubMed: | Central nervous system actions of 2,5-bis(3,4-dimethoxybenzyl) cyclopentyl amine, a peripheral dopamine blocking agent. |
| PubMed: | Toxicity of platinum complexes on hemopoietic precursor cells. |
| PubMed: | Effect of platinum compounds on murine lymphocyte mitogenesis. |
| PubMed: | Antineoplastic activity of platinum complexes of trans-(dl)-1,2-cyclopentanediamine. |
| PubMed: | Response of two strains of L5178Y cells to cis-dichlorobis(cyclopentylamine)platinum(II). II. Differential effects of caffeine. |
| PubMed: | Response of two strains of L5178Y cells to cis-dichlorobis(cyclopentylamine)platinum(II). I. Cross-sensitivity to cis-PAD and UV light. |
| PubMed: | 2,5-Bis(3,4-dimethoxybenzyl)cyclopentylamine, a peripheral dopamine blocking agent. |
| PubMed: | Metabolic studies of the nonnutritive sweeteners cyclopentylmethylsulfamate and cyclopentylsulfamate: determination of metabolites in rat urine. |
| PubMed: | Determination of the nonnutritive sweetener sodium cyclopentylsulfamate and three of its metabolites, cyclopentylamine, cyclopentanone, and cyclopentanol, in urine of rats and rabbits. |
| PubMed: | Action of a platinum complex [cis-dichlorobis (cyclopentylamine)-platinum (II)] on Chinese hamster ovary cells in vitro. |
| PubMed: | The effect of combined treatment with a platinum complex and ionizing radiation on chinese hamster ovary cells in vitro. |
| PubMed: | Proceedings: Cis-dichlorobis (cyclopentylamine) platinum II: action on CHO cells in vitro and interaction with ionizing radiation. |
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