carbon monoxide
carbon monooxide
 
Notes:
carbon monoxide (co). a poisonous colorless, odorless, tasteless gas. it combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. the resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (from merck index, 11th ed) Carbon monoxide, with the chemical formula CO, is a colorless, odorless, and tasteless gas. It is the product of the incomplete combustion of carbon-containing compounds, notably in internal-combustion engines. It consists of one carbon atom covalently bonded to one oxygen atom. It is a gas at room temperature. Carbon monoxide is a significantly toxic gas and is the most common type of fatal poisoning in many countries.Exposures can lead to significant toxicity of the central nervous system and heart. Following poisoning, long-term sequelae often occur. Carbon monoxide can also have severe effects on the fetus of a pregnant woman. Despite its serious toxicity, CO is extremely useful and underpins much modern technology, being a precursor to a myriad of useful - even life-saving - products. Carbon monoxide, though thought of as a pollutant today, has always been present in the atmosphere, chiefly as a product of volcanic activity. It occurs dissolved in molten volcanic rock at high pressures in the earth's mantle. Carbon monoxide contents of volcanic gases vary from less than 0.01% to as much as 2% depending on the volcano. It also occurs naturally in bushfires. Because natural sources of carbon monoxide are so variable from year to year, it is extremely difficult to accurately measure natural emissions of the gas. (wikipedia) [HMDB]
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CAS Number: 630-08-0Picture of molecule3D/inchi
Other: 153929-54-5
ECHA EINECS - REACH Pre-Reg: 211-128-3
FDA UNII: 7U1EE4V452
Nikkaji Web: J1.401.546I
Beilstein Number: 1900508
MDL: MFCD00011320
XlogP3-AA: 0.70 (est)
Molecular Weight: 28.01020000
Formula: C O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: preservatives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 83 P1 Carbon monoxide View - notice PDF
GRN 83 P2 Carbon monoxide View - notice PDF
GRN 143 Carbon monoxide View - notice PDF
GRN 166 Carbon monoxide View - notice PDF
GRN 167 Carbon monoxide View - notice PDF
GRN 188 Carbon monoxide View - notice PDF
GRN 194 Carbon monoxide View - notice PDF
GRN 251 Carbon monoxide View - notice PDF
DG SANTE Food Contact Materials: carbon monoxide
FDA Mainterm (IAUFC): CARBON MONOXIDE
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Physical Properties:
Appearance: colorless gas (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 4.974e+004 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Sigma-Aldrich: Aldrich
For experimental / research use only.
Carbon Monoxide ≥99.0%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-bird - wild LC50 1334 ppm
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.

inhalation-dog LCLo 4000 ppm/46M
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1360, 1935.

inhalation-guinea pig LC50 5718 ppm/4H
Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.

inhalation-human LCLo 4 mg/m3/12H
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BEHAVIORAL: COMA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN
Toksikologicheskii Vestnik. Vol. (4), Pg. 26, 1999.

inhalation-human LCLo 5000 ppm/5M
Tabulae Biologicae. Vol. 3, Pg. 231, 1933.

inhalation-human TCLo 600 mg/m3/10M
BEHAVIORAL: HEADACHE
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(4), Pg. 34, 1987.

inhalation-mammal (species unspecified) LCLo 5000 ppm/5M
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.

inhalation-man LCLo 4000 ppm/30M
"Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 207, 1968.

inhalation-man TCLo 650 ppm/45M
BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS
American Industrial Hygiene Association Journal. Vol. 34, Pg. 212, 1973.

inhalation-mouse LC50 2444 ppm/4H
Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.

inhalation-rabbit LCLo 4000 ppm
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1360, 1935.

inhalation-rat LC50 1807 ppm/4H
Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.

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Safety in Use Information:
Category: preservatives
Recommendation for carbon monoxide usage levels up to:
 not for fragrance use.
 
Recommendation for carbon monoxide flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 630-08-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 281
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 carbon monoxide
Chemidplus: 0000630080
EPA/NOAA CAMEO: hazardous materials
RTECS: 630-08-0
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References:
 carbon monoxide
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 630-08-0
Pubchem (cid): 281
Pubchem (sid): 134976778
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
UM BBD: Search
KEGG (GenomeNet): C00237
HMDB (The Human Metabolome Database): HMDB01361
FooDB: FDB022578
Export Tariff Code: 2811.29.5000
MedlinePlusSupp: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 carbon monooxide
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Articles:
Info: Carbon Monoxide
PubMed: Does switching to a tobacco-free waterpipe product reduce toxicant intake? A crossover study comparing CO, NO, PAH, volatile aldehydes, "tar" and nicotine yields.
PubMed: Acute effects of waterpipe tobacco smoking: a double-blind, placebo-control study.
PubMed: Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis.
PubMed: Enhancement technology improves palatability of normal and callipyge lambs.
PubMed: Comparison of methods for measurement of smoking behavior: mouthpiece-based computerized devices versus direct observation.
PubMed: A randomized, controlled exposure study in adult smokers of full flavor Marlboro cigarettes switching to Marlboro Lights or Marlboro Ultra Lights cigarettes.
PubMed: Effects of aging on beef chuck and loin muscles enhanced with ammonium hydroxide and salt.
PubMed: Toxicological evaluation of potassium sorbate added to cigarette tobacco.
PubMed: Effect of carbon monoxide and high oxygen modified atmosphere packaging and phosphate enhanced, case-ready pork chops.
PubMed: Scope for regulation of cigarette smoke toxicity according to brand differences in published toxicant emissions.
PubMed: Smoking topography predicts abstinence following treatment with nicotine replacement therapy.
PubMed: Quality characteristics of irradiated chicken breast rolls from broilers fed different levels of conjugated linoleic acid.
PubMed: Subjective and discriminative stimulus effects of two de-nicotinized cigarettes with different tar yields.
PubMed: Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice.
PubMed: Indian cigarettes gain popularity, but don't let the flavor fool you.
PubMed: Clinical evaluation of a citric acid inhaler for smoking cessation.
PubMed: Fatty acid oxidation by spores of Penicillium roqueforti.
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