carbon dioxide
dioxidocarbon
 
Notes:
a colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Leavening agent, propellant, aerating agent, preservative. Solvent for supercritical extraction e.g. of caffeine in manufacture of caffeine-free instant coffee. Used in carbonation of beverages, in the frozen food industry and as a component of controlled atmosphere packaging (CAD) to inhibit bacterial growth. Esp. effective against Gram-negative spoilage bacteria, e.g. Pseudomonas A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbon dioxide is produced during respiration by all animals, fungi and microorganisms that depend on living and decaying plants for food, either directly or indirectly. It is, therefore, a major component of the carbon cycle. Additionally, carbon dioxide is used by plants during photosynthesis to make sugars which may either be consumed again in respiration or used as the raw material to produce polysaccharides such as starch and cellulose, proteins and the wide variety of other organic compounds required for plant growth and development. When inhaled at concentrations much higher than usual atmospheric levels, it can produce a sour taste in the mouth and a stinging sensation in the nose and throat. These effects result from the gas dissolving in the mucous membranes and saliva, forming a weak solution of carbonic acid. Carbon dioxide is used by the food industry, the oil industry, and the chemical industry. Carbon dioxide is used to produce carbonated soft drinks and soda water. Traditionally, the carbonation in beer and sparkling wine comes about through natural fermentation, but some manufacturers carbonate these drinks artificially.; As of March 2009[update], carbon dioxide in the Earth's atmosphere is at a concentration of 387 ppm by volume. Atmospheric concentrations of carbon dioxide fluctuate slightly with the change of the seasons, driven primarily by seasonal plant growth in the Northern Hemisphere. Concentrations of carbon dioxide fall during the northern spring and summer as plants consume the gas, and rise during the northern autumn and winter as plants go dormant, die and decay. Carbon dioxide is a greenhouse gas as it transmits visible light but absorbs strongly in the infrared and near-infrared.; CO2 is an acidic oxide: an aqueous solution turns litmus from blue to pink. It is the anhydride of carbonic acid, an acid which is unstable and is known to exist only in aqueous solution.; Carbon dioxide (chemical formula: CO2) is a chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state.; Carbon dioxide in earth's atmosphere is considered a trace gas currently occurring at an average concentration of about 385 parts per million by volume or 582 parts per million by mass. The total mass of atmospheric carbon dioxide is 3.0×1015 kg (3,000 gigatonnes). Its concentration varies seasonally (see graph at right) and also considerably on a regional basis, especially near the ground. In urban areas concentrations are generally higher and indoors they can reach 10 times background levels. Carbon dioxide is a greenhouse gas.; Carbon dioxide is an end product in organisms that obtain energy from breaking down sugars, fats and amino acids with oxygen as part of their metabolism, in a process known as cellular respiration. This includes all plants, animals, many fungi and some bacteria. In higher animals, the carbon dioxide travels in the blood from the body's tissues to the lungs where it is exhaled. In plants using photosynthesis, carbon dioxide is absorbed from the atmosphere.; Carbon dioxide is one of the mediators of local autoregulation of blood supply. If its levels are high, the capillaries expand to allow a greater blood flow to that tissue.; Carbon dioxide is one of the most commonly used compressed gases for pneumatic (pressurized gas) systems in portable pressure tools and combat robots.; Carbon dioxide was one of the first gases to be described as a substance distinct from air. In the seventeenth century, the Flemish chemist Jan Baptist van Helmont observed that when he burned charcoal in a closed vessel, the mass of the resulting ash was much less than that of the original charcoal. His interpretation was that the rest of the charcoal had been transmuted into an invisible substance he termed a "gas" or "wild spirit" (spiritus sylvestre).; Liquid carbon dioxide is a good solvent for many lipophilic organic compounds, and is used to remove caffeine from coffee. First, the green coffee beans are soaked in water. The beans are placed in the top of a column seventy feet (21 m) high. Then supercritical carbon dioxide in fluid form at about 93 degrees Celsius enters at the bottom of the column. The caffeine diffuses out of the beans and into the carbon dioxide
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CAS Number: 124-38-9 
Other(deleted CASRN): 18923-20-1
ECHA EC Number: 204-696-9
FDA UNII: 142M471B3J
Nikkaji Web: J43.600C
Beilstein Number: 1900390
MDL: MFCD00011491
XlogP3-AA: 0.90 (est)
Molecular Weight: 44.00940000
Formula: C O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: propellants, freezing agents, carbonating agents, preservatives, extraction solvents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Google Patents: Search
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 FDA/DG SANTE Petitions, Reviews, Notices:
184.1240 Carbon dioxide View - review
EU SANCO Carbon dioxide View - review
JECFA Food Additive: Carbon Dioxide
GSFA Codex: Carbon dioxide (290)
DG SANTE Food Additives: carbon dioxide
DG SANTE Food Contact Materials: carbon dioxide
FDA Mainterm (SATF):124-38-9 ; CARBON DIOXIDE
FDA Regulation:
FDA PART 165 -- BEVERAGES
Subpart B--Requirements for Specific Standardized Beverages
Sec. 165.110 Bottled water.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.115 French dressing.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.140 Mayonnaise.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.150 Salad dressing.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1240 Carbon dioxide.
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Physical Properties:
Appearance: colorless clear gas (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: -88.46 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 28293.11133 mmHg @ 25.00 °C. (est)
Flash Point: -204.00 °F. TCC ( -131.10 °C. ) (est)
logP (o/w): 0.830 (est)
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
odorless
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: propellants
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Suppliers:
BASF
Carbon Dioxide
Sigma-Aldrich: Aldrich
For experimental / research use only.
Carbon Dioxide ≥99.8%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-human LCLo 9 pph/5M
Tabulae Biologicae. Vol. 3, Pg. 231, 1933.

inhalation-mammal (species unspecified) LCLo 90000 ppm/5M
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.

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Safety in Use Information:
Category: propellants, freezing agents, carbonating agents, preservatives, extraction solvents
Recommendation for carbon dioxide usage levels up to:
 not for fragrance use.
 
Recommendation for carbon dioxide flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Conclusion on the peer review of the pesticide risk assessment of the active substance carbon dioxide
View page or View pdf
Scientific Opinion on the assessment of studies on the use of carbon dioxide for stunning rabbits
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 124-38-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 280
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: nwg
 carbon dioxide
Chemidplus: 0000124389
EPA/NOAA CAMEO: hazardous materials
RTECS: 124-38-9
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References:
 carbon dioxide
Canada Domestic Sub. List: 124-38-9
Pubchem (cid): 280
Pubchem (sid): 134975213
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
UM BBD: Search
KEGG (GenomeNet): C00011
HMDB (The Human Metabolome Database): HMDB01967
FooDB: FDB014084
YMDB (Yeast Metabolome Database): YMDB00912
Export Tariff Code: 2811.21.0000
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
FAO: Carbon dioxide
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 propellants 
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 carbon oxide, di-
 carbonyl oxide
 dioxide, carbon
 dioxidocarbon
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Articles:
Info: Carbon Dioxide
PubMed: Capsaicin: a potent inhibitor of carbonic anhydrase isoenzymes.
PubMed: Utilization of buffered vinegar to increase the shelf life of chicken retail cuts packaged in carbon dioxide.
PubMed: Exploration of potential baker's yeast from sugarcane juice: optimization and evaluation.
PubMed: Inactivation of polyphenol oxidase from watermelon juice by high pressure carbon dioxide treatment.
PubMed: Effect of forage and retail packaging types on meat quality of long-term chilled lamb loins.
PubMed: Olfactory carbon dioxide detection by insects and other animals.
PubMed: Enzyme inactivation in food processing using high pressure carbon dioxide technology.
PubMed: "Green preservatives": combating fungi in the food and feed industry by applying antifungal lactic acid bacteria.
PubMed: Evaluation of gene modification strategies for the development of low-alcohol-wine yeasts.
PubMed: Effects of electron-beam and gamma irradiation treatments on the microbial populations, respiratory activity and sensory characteristics of Tuber melanosporum truffles packaged under modified atmospheres.
PubMed: Physicochemical and phytochemical properties of cold and hot water extraction from Hibiscus sabdariffa.
PubMed: Effects of carbon dioxide and ozone treatments on the volatile composition and sensory quality of dry-cured ham.
PubMed: Shelf-life extension of fresh Tuber aestivum and Tuber melanosporum truffles by modified atmosphere packaging with microperforated films.
PubMed: Review: nanocomposites in food packaging.
PubMed: Supercritical fluid extraction of peach (Prunus persica) almond oil: process yield and extract composition.
PubMed: Enzyme-assisted extraction of flavorings and colorants from plant materials.
PubMed: The neuronal correlates of intranasal trigeminal function-an ALE meta-analysis of human functional brain imaging data.
PubMed: Influence of thermal and dense-phase carbon dioxide pasteurization on physicochemical properties and flavor compounds in Hami melon juice.
PubMed: Influence of composition (CO2 and sugar) on aroma release and perception of mint-flavored carbonated beverages.
PubMed: Lipase-catalyzed ethanolysis of milk fat with a focus on short-chain fatty acid selectivity.
PubMed: Decrease in hydrogen sulfide content during the final stage of beer fermentation due to involvement of yeast and not carbon dioxide gas purging.
PubMed: Effects of aging on beef chuck and loin muscles enhanced with ammonium hydroxide and salt.
PubMed: Improvement of the overall quality of table grapes stored under modified atmosphere packaging in combination with natural antimicrobial compounds.
PubMed: Bubble-included chocolate: relating structure with sensory response.
PubMed: Effect of a gelatin coating on the shelf life of fresh meat.
PubMed: Effect of supercritical carbon dioxide decaffeination on volatile components of green teas.
PubMed: High pressure carbon dioxide inactivation of microorganisms in foods: the past, the present and the future.
PubMed: Opportunities and challenges in high pressure processing of foods.
PubMed: Enhancing the retention of phytochemicals and organoleptic attributes in muscadine grape juice through a combined approach between dense phase CO2 processing and copigmentation.
PubMed: Simultaneous control of apparent extract and volatile compounds concentrations in low-malt beer fermentation.
PubMed: Microbial stability, phytochemical retention, and organoleptic attributes of dense phase CO2 processed muscadine grape juice.
PubMed: Controlled atmosphere storage of wild strawberry fruit (Fragaria vesca L.).
PubMed: How chemical information processing interferes with face processing: a magnetoencephalographic study.
PubMed: Comparison of volatile and semivolatile compounds from commercial cigarette by supercritical fluid extraction and simultaneous distillation extraction.
PubMed: Active food packaging technologies.
PubMed: Sensory threshold of off-flavors caused by proteolysis and lipolysis in milk.
PubMed: Use of adsorbent and supercritical carbon dioxide to concentrate flavor compounds from orange oil.
PubMed: Effect of high-oxygen and high-carbon-dioxide atmospheres on strawberry flavor and other quality traits.
PubMed: Modified atmosphere packaged cheddar cheese shreds: influence of fluorescent light exposure and gas type on color and production of volatile compounds.
PubMed: Countercurrent supercritical fluid extraction and fractionation of alcoholic beverages.
PubMed: Formulations and processing of yogurt affect the microbial quality of carbonated yogurt.
PubMed: Infusion of volatile flavor compounds into low-density polyethylene.
PubMed: Combined effects of carbon dioxide addition and barrier films on microbial and sensory changes in pasteurized milk.
PubMed: Thawed cod fillets spoil less rapidly than unfrozen fillets when stored under modified atmosphere at 2 degrees C.
PubMed: Extraction of natural substances with dense gases.
PubMed: Flavor and flatulence factors in soybean protein products.
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