beta-propiolactone
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      57-57-8 Propiolactone >95%
      Reacts with bacteriphage DNA causing inactivation, repair and recombination.
       
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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      Products List: View
      Product(s):
      W91701 BETA-PROPIOLACTONE
       
Synonyms   Articles   Notes   Search
CAS Number: 57-57-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 200-340-1
FDA UNII: 6RC3ZT4HB0
Nikkaji Web: J2.327B
Beilstein Number: 0001360
XlogP3-AA: -0.20 (est)
Molecular Weight: 72.06328000
Formula: C3 H4 O2
NMR Predictor: Predict (works with chrome or firefox)
Category: indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm (IAUFC):57-57-8 ; PROPIOLACTONE
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.14600 @  25.00 °C.
Flash Point: 158.00 °F. TCC ( 70.00 °C. )
Soluble in:
 water, 3.70E+05 mg/L @ 25 °C (exp)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
Propiolactone >95%
Odor: characteristic
Use: Reacts with bacteriphage DNA causing inactivation, repair and recombination.
Synerzine
BETA-PROPIOLACTONE
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  405 mg/kg
JNCI, Journal of the National Cancer Institute. Vol. 62, Pg. 911, 1979.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LC50 25 ppm/6H
"Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 497, 1986.

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Safety in Use Information:
Category: indirect food additives: adhesives and components of coatings
Recommendation for beta-propiolactone usage levels up to:
 not for fragrance use.
 
Recommendation for beta-propiolactone flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA-Iris: IRIS
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 57-57-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 2365
National Institute of Allergy and Infectious Diseases: Data
 oxetan-2-one
Chemidplus: 0000057578
EPA/NOAA CAMEO: hazardous materials
RTECS: 57-57-8
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References:
 oxetan-2-one
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 57-57-8
Pubchem (cid): 2365
Pubchem (cas): 57-57-8
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C19297
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2932.29.5050
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 betaprone
 hydracrylic acid beta-lactone
3-hydroxypropionic acid lactone
 oxetan-2-one
2-oxetanone
beta-propanoic acid lactone
3-propanolide
3-propiolactone
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