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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 442.10 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 456.00 °F. TCC ( 235.30 °C. ) (est)
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| logP (o/w): | 3.360 (est) |
| Soluble in: |
| | water, 0.31 mg/L @ 25 °C (exp) | | | water, 72.76 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-mouse LD50 180 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#06773
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for 2,6-dihydroxyanthraquinone usage levels up to: | | | not for fragrance use.
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| Recommendation for 2,6-dihydroxyanthraquinone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 9,10- | anthracenedione, 2,6-dihydroxy- | | | anthraflavic acid | | | anthraflavin | | | anthraquinone, 2,6-dihydroxy- | | 2,6- | dihydroxyanthracene-9,10-dione |
Articles:
| PubMed: | Determination of the optical GAP in thin films of amorphous dilithium phthalocyanine using the Tauc and Cody models. |
| PubMed: | Phenol transformation photosensitised by quinoid compounds. |
| PubMed: | Electrical and optical properties of copper and nickel molecular materials with tetrabenzo [b,f,j,n] [1,5,9,13] tetraazacyclohexadecine thin films grown by the vacuum thermal evaporation technique. |
| PubMed: | Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. |
| PubMed: | Interaction of anthracene and its oxidative derivatives with human serum albumin. |
| PubMed: | The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases. |
| PubMed: | Evidence for phosphorylation requirement for human bilirubin UDP-glucuronosyltransferase (UGT1A1) activity. |
| PubMed: | Biosynthesis of drug glucuronides for use as authentic standards. |
| PubMed: | Inhibition and active sites of UDP-glucuronosyltransferases 2B7 and 1A1. |
| PubMed: | Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes. |
| PubMed: | Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. |
| PubMed: | Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. |
| PubMed: | Inhibitors of cAMP-dependent protein kinase impair long-term memory formation in day-old chicks. |
| PubMed: | Structure-activity relationships of anthraquinones as inhibitors of 7-ethoxycoumarin O-deethylase and mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline. |
| PubMed: | Extrapolation of in vitro antimutagenicity to the in vivo situation: the case for anthraflavic acid. |
| PubMed: | Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals. |
| PubMed: | Induction of rat hepatic cytochrome P-450 I proteins by the antimutagen anthraflavic acid. |
| PubMed: | Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice. |
| PubMed: | Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action. |
| PubMed: | Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity. |
| PubMed: | Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols. |
| PubMed: | Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols. |
| PubMed: | Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. |
| PubMed: | Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system. |
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