| PubMed: | Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. |
| PubMed: | Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones. |
| PubMed: | Third-generation breathing metal-organic framework with selective, stepwise, reversible, and hysteretic adsorption properties. |
| PubMed: | Broad and potent cellular and humoral immune responses after a second late HIV-modified vaccinia virus ankara vaccination in HIV-DNA-primed and HIV-modified vaccinia virus Ankara-boosted Swedish vaccinees. |
| PubMed: | Identification of labile Zn sites in drug-target proteins. |
| PubMed: | Convergent Ca2+ and Zn2+ signaling regulates apoptotic Kv2.1 K+ currents. |
| PubMed: | FT-IR, micro-Raman and UV-vis spectroscopic and quantum chemical investigations of free 2,2'-dithiodipyridine and its metal (Co, Cu and Zn) halide complexes. |
| PubMed: | Composite blends of gold nanorods and poly(t-butylacrylate) beads as new substrates for SERS. |
| PubMed: | Novel chiral derivatization reagents possessing a pyridylthiourea structure for enantiospecific determination of amines and carboxylic acids in high-throughput liquid chromatography and electrospray-ionization mass spectrometry for chiral metabolomics identification. |
| PubMed: | Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals. |
| PubMed: | Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine. |
| PubMed: | Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS. |
| PubMed: | Dichloridobis(pyridine-2-thiol-ato-κ²N,S)tin(IV): a new polymorph. |
| PubMed: | Toxic role of K+ channel oxidation in mammalian brain. |
| PubMed: | Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy. |
| PubMed: | Fermentation, fractionation and purification of streptokinase by chemical reduction method. |
| PubMed: | S-glutathionylation of troponin I (fast) increases contractile apparatus Ca2+ sensitivity in fast-twitch muscle fibres of rats and humans. |
| PubMed: | Hyperforin changes the zinc-storage capacities of brain cells. |
| PubMed: | Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. |
| PubMed: | Purely heterometallic lanthanide(III) macrocycles through controlled assembly of disulfide bonds for dual color emission. |
| PubMed: | Modulation of contractile apparatus Ca2+ sensitivity and disruption of excitation-contraction coupling by S-nitrosoglutathione in rat muscle fibres. |
| PubMed: | Toxicity and metabolism of copper pyrithione and its degradation product, 2,2'-dipyridyldisulfide in a marine polychaete. |
| PubMed: | Plasmacytoid dendritic cells, Janus-faced sentinels: progesterone, guilty or innocent? |
| PubMed: | Strong HIV-specific CD4+ and CD8+ T-lymphocyte proliferative responses in healthy individuals immunized with an HIV-1 DNA vaccine and boosted with recombinant modified vaccinia virus ankara expressing HIV-1 genes. |
| PubMed: | HIV-1 impairs in vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells. |
| PubMed: | Simple and practical derivatization procedure for enhanced detection of carboxylic acids in liquid chromatography-electrospray ionization-tandem mass spectrometry. |
| PubMed: | Inactivation of respiratory syncytial virus by zinc finger reactive compounds. |
| PubMed: | Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation. |
| PubMed: | Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239. |
| PubMed: | Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence. |
| PubMed: | Hepatic ischemia induced immediate oxidative stress after reperfusion and determined the severity of the reperfusion-induced damage. |
| PubMed: | Thiol protection in membrane protein purifications: a study with phage holins. |
| PubMed: | Dendritic cell differentiation and maturation in the presence of HIV type 2 envelope. |
| PubMed: | Enhanced antibody responses elicited by a CpG adjuvant do not improve the protective effect of an aldrithiol-2-inactivated simian immunodeficiency virus therapeutic AIDS vaccine. |
| PubMed: | Inhibition of acetylcholinesterase by metabolites of copper pyrithione (CuPT) and its possible involvement in vertebral deformity of a CuPT-exposed marine teleostean fish. |
| PubMed: | Statistical optimization of the silylation reaction of a mercaptosilane with silanol groups on the surface of silica gel. |
| PubMed: | In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection. |
| PubMed: | Size-dependence of Fermi energy of gold nanoparticles loaded on titanium(iv) dioxide at photostationary state. |
| PubMed: | Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells. |
| PubMed: | Immunotherapy with internally inactivated virus loaded dendritic cells boosts cellular immunity but does not affect feline immunodeficiency virus infection course. |
| PubMed: | Oxidation of myofilament protein sulfhydryl groups reduces the contractile force and its Ca2+ sensitivity in human cardiomyocytes. |
| PubMed: | Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease. |
| PubMed: | Exploration of the polar microenvironment around the reactive cysteine in rabbit muscle creatine kinase. |
| PubMed: | Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1. |
| PubMed: | Evaluation of aldrithiol-2-inactivated preparations of HIV type 1 subtypes A, B, and D as reagents to monitor T cell responses. |
| PubMed: | A dendritic cell-based vaccine for treating HIV infection: background and preliminary results. |
| PubMed: | Invariant Thr244 is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans. |
| PubMed: | Rapid determination of histamine and its metabolites in mice hair by ultra-performance liquid chromatography with time-of-flight mass spectrometry. |
| PubMed: | CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection. |
| PubMed: | Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. |
| PubMed: | Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis. |
| PubMed: | In vitro proteolysis of phosphoenolpyruvate carboxylase from developing castor oil seeds by an endogenous thiol endopeptidase. |
| PubMed: | Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells. |
| PubMed: | Evidence that the species barrier of human immunodeficiency virus-1 does not extend to uptake by the blood--brain barrier: comparison of mouse and human brain microvessels. |
| PubMed: | Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization. |
| PubMed: | Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins. |
| PubMed: | Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. |
| PubMed: | Development of reactive thiol-modified monolithic capillaries and in-column surface functionalization by radical addition of a chromatographic ligand for capillary electrochromatography. |
| PubMed: | Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis. |
| PubMed: | Direct heterogeneous electron transfer of theophylline oxidase. |
| PubMed: | CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells. |
| PubMed: | Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo. |
| PubMed: | Spectroelectrochemical study of heme- and molybdopterin cofactor-containing chicken liver sulphite oxidase. |
| PubMed: | Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells. |
| PubMed: | Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses. |
| PubMed: | Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-alpha. |
| PubMed: | Sites, mechanism of action and lack of reversibility of primate lentivirus inactivation by preferential covalent modification of virion internal proteins. |
| PubMed: | Determination of homocysteine in human plasma by micellar electrokinetic chromatography and in-capillary detection reaction with 2,2'-dipyridyl disulfide. |
| PubMed: | [Functionalization of oligonucleotides containing internucleotide phosphoamide bonds]. |
| PubMed: | SH oxidation coordinates subunits of rat brain ryanodine receptor channels activated by calcium and ATP. |
| PubMed: | Thiol oxidation by 2,2'-dithiodipyridine induced calcium mobilization in MG63 human osteosarcoma cells. |
| PubMed: | Effects of oxidation and reduction on contractile function in skeletal muscle fibres of the rat. |
| PubMed: | Adsorption of 2,2'-dipyridyl disulfide on Au/Pt core/shell bimetallic clusters loaded on TiO2: fine control of adsorptivity for organosulfur compounds. |
| PubMed: | Therapeutic dendritic-cell vaccine for simian AIDS. |
| PubMed: | Design and synthesis of a hydrophilic fluorescent derivatization reagent for carboxylic acids, 4-N-(4-N-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole (NBD-PZ-NH2), and its application to capillary electrophoresis with laser-induced fluorescence detection. |
| PubMed: | Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. |
| PubMed: | Quantitative measurement of fusion of HIV-1 and SIV with cultured cells using photosensitized labeling. |
| PubMed: | Infectious and whole inactivated simian immunodeficiency viruses interact similarly with primate dendritic cells (DCs): differential intracellular fate of virions in mature and immature DCs. |
| PubMed: | Determination of whole blood cholinesterase in different animal species using specific substrates. |
| PubMed: | In vitro human immunodeficiency virus eradication by autologous CD8(+) T cells expanded with inactivated-virus-pulsed dendritic cells. |
| PubMed: | A fluorogenic reagent, 4-mercapto-7-methylthio-2,1,3-benzoxadiazole for carboxylic acids, designed by prediction of the fluorescence intensity. |
| PubMed: | Biochemical and X-ray crystallographic studies on shikimate kinase: the important structural role of the P-loop lysine. |
| PubMed: | p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis. |
| PubMed: | HIV-1 gp120 stimulates the production of beta-chemokines in human peripheral blood monocytes through a CD4-independent mechanism. |
| PubMed: | Solid-state structure and solution behavior of eight-coordinate Sm(III) poly(pyrazolyl)borate compounds. |
| PubMed: | Specific thiol determination by micellar electrokinetic chromatography and on-column detection reaction with 2,2'-dipyridyldisulfide. |
| PubMed: | Use of whole blood for spectrophotometric determination of cholinesterase activity in dogs. |
| PubMed: | Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. |
| PubMed: | Block of sodium channels by divalent mercury: role of specific cysteinyl residues in the P-loop region. |
| PubMed: | Effect of sulfhydryl reagents on the regulatory system of the L-type Ca channel in frog ventricular myocytes. |
| PubMed: | Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells. |
| PubMed: | Comparison of different diluents and chromophores for spectrophotometric determination of livestock blood cholinesterase activity. |
| PubMed: | Use of dipyridyl-dithio substrates to measure directly the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes. |
| PubMed: | 2,2'-Bispyridyl disulfide rapidly induces intramolecular disulfide bonds in peptides. |
| PubMed: | Kvbeta1.2 subunit coexpression in HEK293 cells confers O2 sensitivity to kv4.2 but not to Shaker channels. |
| PubMed: | Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine. |
| PubMed: | CD4(+) T-lymphocyte depletion in human lymphoid tissue ex vivo is not induced by noninfectious human immunodeficiency virus type 1 virions. |
| PubMed: | Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins. |
| PubMed: | Screening system for urease inhibitors using 13C-NMR. |
| PubMed: | Inhibition of Friend virus replication by a compound that reacts with the nucleocapsid zinc finger: anti-retroviral effect demonstrated in vivo. |
| PubMed: | Synthesis of 3'-thioribonucleosides and their incorporation into oligoribonucleotides via phosphoramidite chemistry. |
| PubMed: | A classical enzyme active center motif lacks catalytic competence until modulated electrostatically. |
| PubMed: | Highly ordered molten globule-like state of ovalbumin at acidic pH: native-like fragmentation by protease and selective modification of Cys367 with dithiodipyridine. |
| PubMed: | Stabilising and destabilising modifications of cysteines in the E. coli outer membrane porin protein OmpC. |
| PubMed: | Actions of sulfhydryl reagents on single ryanodine receptor Ca(2+)-release channels from sheep myocardium. |
| PubMed: | Rapid kinetic studies of SH oxidation-induced calcium release from sarcoplasmic reticulum vesicles. |
| PubMed: | Thiol oxidation by 2,2'-dithiodipyridine causes a reversible increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. Role for inositol 1,4,5-trisphosphate-sensitive Ca2+ stores. |
| PubMed: | Sensitive analytical method for the novel H1-receptor antagonist HSR-609 in human plasma and urine by high-performance liquid chromatography with pre-column fluorescent derivatization. |
| PubMed: | Thiol oxidation and cytochrome P450-dependent metabolism of CCl4 triggers Ca2+ release from liver microsomes. |
| PubMed: | Characterization of intermediates in the oxidation of zinc fingers in human immunodeficiency virus type 1 nucleocapsid protein P7. |
| PubMed: | Rapid kinetic studies and structural determination of a cysteine proteinase mutant imply that residue 158 in caricain has a major effect upon the ability of the active site histidine to protonate a dipyridyl probe. |
| PubMed: | Effects of reducing agents and oxidants on excitation-contraction coupling in skeletal muscle fibres of rat and toad. |
| PubMed: | Heavy metals inhibit Pi-induced currents through human brush-border NaPi-3 cotransporter in Xenopus oocytes. |
| PubMed: | Effect of anionic surfactant on the reaction of 2,2(1)-dithiobispyridine with bovine oxyhemoglobin as a function of temperature. |
| PubMed: | Hepatotoxic effects of SH-reagents in human and rat hepatocyte cultures and in situ perfused rat livers. |
| PubMed: | Automated spectrophotometric method using 2,2'-dithiodipyridine acid for determination of cholinesterase in whole blood. |
| PubMed: | Characterization of the electrostatic perturbation of a catalytic site (Cys)-S-/(His)-Im+H ion-pair in one type of serine proteinase architecture by kinetic and computational studies on chemically mutated subtilisin variants. |
| PubMed: | Characterization of human adenovirus proteinase activity in disrupted virus particles. |
| PubMed: | Functional consequences of sulfhydryl modification in the pore-forming subunits of cardiovascular Ca2+ and Na+ channels. |
| PubMed: | Human class 1 aldehyde dehydrogenase. Expression and site-directed mutagenesis. |
| PubMed: | Enantiospecific determination of ibuprofen in rat plasma using chiral fluorescence derivatization reagent, (-)-2-[4-(1-aminoethyl)phenyl]-6- methoxybenzoxazole. |
| PubMed: | Mechanism of cyclosporin A biosynthesis. Evidence for synthesis via a single linear undecapeptide precursor. |
| PubMed: | Characterization of the covalent chromatography of thymidylate synthase on thiopropyl-Sepharose 6B. |
| PubMed: | Synthesis of bleomycin A5 oligonucleotide derivatives and site-specific cleavage of the DNA target. |
| PubMed: | Labeling of cysteine 231 in acetylcholinesterase from Torpedo nobiliana by the active-site directed reagent, 1-bromo-2-[14C] pinacolone. Effects of 2,2'-dipyridyl disulfide and other sulfhydryl reagents. |
| PubMed: | Ionizable groups linked to the reaction of 2,2'-dithiobispyridine with hemoglobin. |
| PubMed: | [Modification of a disulfide in the hinge region of rabbit IgG and study of the interaction of polyvalent ferritin antigen, protein A, and anti-IgG]. |
| PubMed: | Evidence for independent molecular identity and functional interaction of the haemagglutinin and cysteine proteinase (gingivain) of Porphyromonas gingivalis. |
| PubMed: | Assessment of the relative cytotoxicity of Porphyromonas gingivalis cells, products, and components on human epithelial cell lines. |
| PubMed: | Effect of sulfhydryl compounds on ATP-stimulated H+ transport and Cl- uptake in rabbit renal cortical endosomes. |
| PubMed: | Reactivity of the essential thiol of Klebsiella aerogenes urease. Effect of pH and ligands on thiol modification. |
| PubMed: | Unexpectedly facile synthesis of symmetrical P1,P2-dinucleoside-5'pyrophosphates. |
| PubMed: | Changes of polymerization and conformation of hemoglobin S induced by thiol reagents. |
| PubMed: | Reactive disulfide compounds induce Ca2+ release from cardiac sarcoplasmic reticulum. |
| PubMed: | Reaction between sheep liver mitochondrial aldehyde dehydrogenase and various thiol-modifying reagents. |
| PubMed: | New segment synthesis of alpha-inhibin-92 by the acyl disulfide method. |
| PubMed: | Properties of the principal anion-exchange mechanism in human neutrophils. |
| PubMed: | Substrate-derived two-protonic-state electrophiles as sensitive kinetic specificity probes for cysteine proteinases. Activation of 2-pyridyl disulphides by hydrogen-bonding. |
| PubMed: | Disulfide bond formation between the active-site thiol and one of the several free thiol groups of chymopapain. |
| PubMed: | Effects of diethylstilbestrol, 2,2'-dithiodipyridine, and chloral hydrate on the esterase activity of sheep liver cytoplasmic aldehyde dehydrogenase. |
| PubMed: | Rat hepatic cholesterol 7 alpha-hydroxylase: biochemical properties and comparison to constitutive and xenobiotic-inducible cytochrome P-450 enzymes. |
| PubMed: | Purification of cathepsin B by a new form of affinity chromatography. |
| PubMed: | Chymopapain A. Purification and investigation by covalent chromatography and characterization by two-protonic-state reactivity-probe kinetics, steady-state kinetics and resonance Raman spectroscopy of some dithioacyl derivatives. |
| PubMed: | The effect of 5,5'-dithiobis(1-methyltetrazole) on cytoplasmic aldehyde dehydrogenase and its implications for cephalosporin-alcohol reactions. |
| PubMed: | Purification and properties of mitochondrial monoamine oxidase type A from human placenta. |
| PubMed: | High concentrations of aldehydes slow the reaction of cytoplasmic aldehyde dehydrogenase with thiol-group modifiers. |
| PubMed: | Abnormal redox status of membrane-protein thiols in sickle erythrocytes. |
| PubMed: | Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and a rapid spectroscopic titration of cathepsin H at pH 3-4. |
| PubMed: | Modification of thiol groups in cytoplasmic aldehyde dehydrogenase. |
| PubMed: | Reaction of hemerythrin with disulfides. |
| PubMed: | The time course of the interaction of sheep liver cytoplasmic aldehyde dehydrogenase with 2,2'- and 4,4'-dithiodipyridine: a comparison with the action of disulfiram. |
| PubMed: | Natural structural variation in enzymes as a tool in the study of mechanism exemplified by a comparison of the catalytic-site structure and characteristics of cathepsin B and papain. pH-dependent kinetics of the reactions of cathepsin B from bovine spleen and from rat liver with a thiol-specific two-protonic-state probe (2,2'-dipyridyl disulphide) and with a specific synthetic substrate (N-alpha-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide). |
| PubMed: | Multiple oxidation products of sulfhydryl groups near the active site of thiolase I from porcine heart. |
| PubMed: | The thiol groups of the Folch-Pi protein from bovine white matter. Exposure, reactivity and significance. |
| PubMed: | The activation of aldehyde dehydrogenase by diethylstilboestrol and 2,2'-dithiodipyridine. |
| PubMed: | Characterization of papaya peptidase A as a cysteine proteinase of Carica papaya L. with active-centre properties that differ from those of papain by using 2,2'-dipyridyl disulphide and 4-chloro-7-nitrobenzofurazan as reactivity probes. Use of two-protonic-state electrophiles in the identification of catalytic-site thiol groups. |
| PubMed: | Further studies of the action of disulfiram and 2,2'-dithiodipyridine on the dehydrogenase and esterase activities of sheep liver cytoplasmic aldehyde dehydrogenase. |
| PubMed: | Synthesis of macrolide prostaglandin analogs. |
| PubMed: | Effect of homogeneous magnetic fields on responses to toxic stimulation in Spirostomum ambiguum. |
| PubMed: | A rapid and sensitive spectrophotometric method for determination of hydrogen sulfide with 2,2'-dipyridyl disulfide. |
| PubMed: | Effects of the reduction and S-carbamidomethylation on the conformation, activity and heparin-binding capacity of human antithrombin III. |
| PubMed: | Studies on the effect of reagent and protein charges on reactivity of the beta 93 sulfhydryl group of human hemoglobin using selected mutations. |
| PubMed: | Reactivity of the thiol group in human and bovine albumin at pH 3--9, as measured by exchange with 2,2'-dithiodipyridine. |
| PubMed: | Reversible activation of rat liver microsomal glutathione S-transferase activity by 5,5'-dithiobis(2-nitrobenzoic acid) and 2,2'-dipyridyl disulfide. |
| PubMed: | A kinetic method for the study of solvent environments of thiol groups in proteins involving the use of a pair of isomeric reactivity probes and a differential solvent effect. Investigation of the active centre of ficin by using 2,2'- and 4,4'- dipyridyl disulphides as reactivity probes. |
| PubMed: | 2,2'-Dithiodipyridine activates aldehyde dehydrogenase and protects the enzyme against inactivation by disulfiram. |
| PubMed: | The modification of cholinesterase activity by 5,5'-dithiobis-(2-nitrobenzoic acid) included in the coupled spectrophotometric assay. Evidence for a non-catalytic substrate-binding site. |