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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 345.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 290.00 °F. TCC ( 143.10 °C. ) (est)
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| logP (o/w): | 2.310 (est) |
| Soluble in: |
| | water, 813.1 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for 7-ethoxycoumarin usage levels up to: | | | not for fragrance use.
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| Recommendation for 7-ethoxycoumarin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2H-1- | benzopyran-2-one, 7-ethoxy- | | 7- | ethoxy-1-benzopyran-2-one | | 7- | ethoxy-2H-1-benzopyran-2-one | | 7- | ethoxy-2H-chromen-2-one | | 7- | ethoxychromen-2-one |
Articles:
| PubMed: | Metabolism of 7-ethoxycoumarin, safrole, flavanone and hydroxyflavanone by cytochrome P450 2A6 variants. |
| PubMed: | Influence of cigarette smoke on the L-ascorbic acid metabolism and the activities of drug-metabolizing enzyme in rats. |
| PubMed: | Thyme (Thymus vulgaris L.) leaves and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver. |
| PubMed: | Allogeneic cell therapy for the treatment of liver disease. |
| PubMed: | Inhibition of cytochrome p450 enzymes by enrofloxacin in the sea bass (Dicentrarchus labrax). |
| PubMed: | Antimutagenicity of ethanol extracts of bee glue against environmental mutagens. |
| PubMed: | Beta2-agonist abuse in food producing animals: use of in vitro liver preparations to assess biotransformation and potential target residues for surveillance. |
| PubMed: | Modulation of cytochrome P-450-dependent monooxygenases, glutathione and glutathione S-transferase in rat liver by geniposide from Gardenia jasminoides. |
| PubMed: | Use of fresh and cryopreserved hepatocytes to study the metabolism of pesticides in food-producing animals and rats. |
| PubMed: | Metabolism of [ring-U-14C] agaritine by precision-cut rat, mouse and human liver and lung slices. |
| PubMed: | Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices. |
| PubMed: | Effect of swimming exercise and ethanol on rat liver P450-dependent monooxygenases. |
| PubMed: | Influence of metabolism in skin on dosimetry after topical exposure. |
| PubMed: | Comparison of maturation of drug-metabolizing enzymes in calves with functioning or nonfunctioning rumen. |
| PubMed: | Food restriction and stimulation of monooxygenation of p-nitroanisole in perfused rat liver. |
| PubMed: | Studies on the acute effects of coumarin and some coumarin derivatives in the rat. |
| PubMed: | Induction of cytochrome P-450-dependent enzyme activities in cultured rat liver slices. |
| PubMed: | Effects of soya bean flakes and liquorice root extract on enzyme induction and toxicity in B6C3F1 mice. |
| PubMed: | Enzyme induction of the early chick embryo by airborne particulate extracts. |
| PubMed: | Suppression of benzo[a]pyrene metabolism by accumulation of triacylglycerols in rat hepatocytes: effect of high-fat and food-restricted diets. |
| PubMed: | Enzyme activities associated with carcinogen metabolism in liver and nonhepatic tissues of rats maintained on high fat and food-restricted diets. |
| PubMed: | Maturational development of drug-metabolizing enzymes in sheep. |
| PubMed: | Maturational development of drug-metabolizing enzymes in dogs. |
| PubMed: | Dietary selenium protects against acute toxicity of T-2 toxin in rats. |
| PubMed: | Metabolism of xenobiotics during percutaneous penetration: role of absorption rate and cutaneous enzyme activity. |
| PubMed: | Studies of cytotoxicity and metabolic competence with the rat intestinal cell line IEC-17. |
| PubMed: | Mechanisms of anti-carcinogenesis by indole-3-carbinol. Studies of enzyme induction, electrophile-scavenging, and inhibition of aflatoxin B1 activation. |
| PubMed: | Interactions of heterocyclic Maillard products with the hepatic microsomal monooxygenase system. |
| PubMed: | Effects of the fungicide prochloraz on xenobiotic metabolism in rainbow trout: in vivo induction. |
| PubMed: | Difference between species in response to a 3,5-dichloropyridyloxyphenoxy compound: induction of cytochrome P-450 and/or peroxisome proliferation. |
| PubMed: | Effects of dietary Schizandra chinensis, brussels sprouts and Illicium verum extracts on carcinogen metabolism systems in mouse liver. |
| PubMed: | Comparison of the effects of various flavonoids on ethoxycoumarin deethylase activity of rat intestinal and hepatic microsomes. |
| PubMed: | Potent induction of human placental mono-oxygenase activity by previous dietary exposure to polychlorinated biphenyls and their thermal degradation products. |
| PubMed: | Effects of semisynthetic diets on xenobiotic metabolizing enzyme activity and morphology of small intestinal mucosa in humans. |
| PubMed: | Adipose tissue content as a modifier of the tissue distribution, biological effects, and excretion of a hexachlorobiphenyl in C57BL/6J and DBA/JBOMf mice. |
| PubMed: | Hepatic biotransformation in farmed blue fox and raccoon dog. |
| PubMed: | Drug-oxidizing mono-oxygenase system in liver microsomes of goldfish (Carassius auratus). |
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