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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.13700 to 1.14200 @ 20.00 °C.
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| Pounds per Gallon - (est).: | 9.472 to 9.514
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| Refractive Index: | 1.54200 to 1.54600 @ 20.00 °C.
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| Melting Point: | -4.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 187.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 192.00 to 193.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.242000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 130.00 °F. TCC ( 54.44 °C. )
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| logP (o/w): | 0.430 |
| Soluble in: |
| | water, 4.774e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Flavor Type: fruity |
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| | fruity |
Taste Description:
| fruity |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LDLo 1600 mg/kg Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for 4-pyridine carboxaldehyde usage levels up to: | | | not for fragrance use.
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| Recommendation for 4-pyridine carboxaldehyde flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4- | formylpyridine | | p- | formylpyridine | | iso | nicotinaldehyde | | iso | nicotinic aldehyde | | 4- | pyridine aldehyde | | | pyridine-4-aldehyde | | | pyridine-4-carbaldehyde | | | pyridine-4-carboxaldehyde | | | pyridine-4-ylcarboxaldehyde | | 4- | pyridinealdehyde | | p- | pyridinealdehyde | | 4- | pyridinecarboxaldehyde | | (4- | pyridinecarboxaldehyde) | | 4- | pyridylaldehyde |
Articles:
| US Patents: | 3,952,024 - Furfurylthioacetone |
| PubMed: | The involvement of P2Y12 receptors, NADPH oxidase, and lipid rafts in the action of extracellular ATP on synaptic transmission at the frog neuromuscular junction. |
| US Patents: | Certain 2,5-dimethyl-3-thiopyrazines |
| PubMed: | [Live cell fluorescent imaging and cytotoxicity assessment of pH fluorescent probe based on styrylcyanine dyes]. |
| PubMed: | Heterogeneous carbon gels: N-doped carbon xerogels from resorcinol and N-containing heterocyclic aldehydes. |
| PubMed: | Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. |
| PubMed: | Comparative studies of structural, thermal, optical, and electrochemical properties of azines with different end groups with their azomethine analogues toward application in (opto)electronics. |
| PubMed: | A novel ruthenium(II)-cobaloxime supramolecular complex for photocatalytic H2 evolution: synthesis, characterisation and mechanistic studies. |
| PubMed: | The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors. |
| PubMed: | Preparation and characterization of N-heterocyclic chitosan derivative based gels for biomedical applications. |
| PubMed: | Excitation-energy dependence of the phosphorescence quantum yields of pyridinecarboxaldehyde vapors. |
| PubMed: | Probing lead(II) bonding environments in 4-substituted pyridine adducts of (2,6-Me2C6H3S)2Pb: an X-ray structural and solid-state 207Pb NMR study. |
| PubMed: | Emission spectra and electronic energy levels of the rotational isomers of pyridinecarboxaldehyde vapors. |
| PubMed: | Enhancement of metal-metal coupling at a considerable distance by using 4-pyridinealdazine as a bridging ligand in polynuclear complexes of rhenium and ruthenium. |
| PubMed: | Noncentrosymmetric organic solids with very strong harmonic generation response. |
| PubMed: | Dibromo(pyridoxal semicarbazone-kappa3N1,O3,O3')copper(II). |
| PubMed: | Pillared, 3D metal-organic frameworks with rectangular channels. Synthesis and characterization of coordination polymers based on tricadmium carboxylates. |
| PubMed: | Synthesis and calcium channel-modulating effects of alkyl (or cycloalkyl) 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridyl-5-pyridinecarboxylate racemates and enantiomers. |
| PubMed: | Large Molecular Quadratic Hyperpolarizabilities in Donor/Acceptor-Substituted trans-Tetraammineruthenium(II) Complexes. |
| PubMed: | Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers. |
| PubMed: | Aromatase inhibitors. Syntheses and structure-activity studies of novel pyridyl-substituted indanones, indans, and tetralins. |
| PubMed: | New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives. |
| PubMed: | Relationship between structure and antineoplastic activity of (arylsulfonyl)hydrazones of 4-pyridinecarboxaldehyde. |
| PubMed: | The binding affinity of amphetamine to 4-pyridinecarboxaldehyde and the coenzymes pyridoxal and pyridoxal-5-phosphate. |
| PubMed: | [Reactivation of phosphorylated acetylcholinesterase (AChE): quaternary salts of vinylogous pyridinaldoxims (author's transl)]. |
| PubMed: | [Quantitative determination of alkylating cytostatics on TLC plate with 4-pyridinecarboxaldehyde-2-benzothiazolylhydrazone]. |
| PubMed: | 5-(2-Chloroethyl)-3-hydroxy-2-methyl-4-pyridinecarboxaldehyde ( 5 -pyridoxal methyl chloride) and its reaction with N -acetyl-L-lysine to form a new cyclic imino acid derivative of homopyridoxal. |
| PubMed: | Xanthine oxidase catalyzed oxidation of aldehydes. Oxidation of aliphatic aldehydes and 2- and 4-pyridinecarboxaldehyde. |
| PubMed: | Photoinactivation of aldolases by pyridoxal phosphate and its analogues. |
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