4-hydroxy-6-methyl-2-pyrone
4H-pyran-4-one, 2-hydroxy-6-methyl-
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
      Facebook
      Twitter
      Linkedin
      Blog
      Get the App!
      Product(s):
      675-10-5 4-Hydroxy-6-methyl-2-pyrone 98%
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
      Facebook
      Twitter
      Instagram
      Linkedin
      Product(s):
      H0715 4-Hydroxy-6-methyl-2-pyrone >98.0%(GC)
       
Synonyms   Articles   Notes   Search
CAS Number: 675-10-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 211-619-2
FDA UNII: S1S883S4EE
Nikkaji Web: J86H
Beilstein Number: 0113815
MDL: MFCD00006641
XlogP3-AA: 0.50 (est)
Molecular Weight: 126.11142000
Formula: C6 H6 O3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 2.996e+005 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
BOC Sciences
For experimental / research use only.
4-Hydroxy-6-methyl-2-pyrone 98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
4-Hydroxy-6-methyl-2-pyrone 98%
TCI AMERICA
For experimental / research use only.
4-Hydroxy-6-methyl-2-pyrone >98.0%(GC)
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
subcutaneous-mouse LD50 3200 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 128, Pg. 126, 1960.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for 4-hydroxy-6-methyl-2-pyrone usage levels up to:
 not for fragrance use.
 
Recommendation for 4-hydroxy-6-methyl-2-pyrone flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 675-10-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 54675757
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 4-hydroxy-6-methylpyran-2-one
Chemidplus: 0000675105
RTECS: UQ1000000 for cas# 675-10-5
Synonyms   Articles   Notes   Search   Top
References:
 4-hydroxy-6-methylpyran-2-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 54675757
Pubchem (sid): 134978316
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C02752
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2932.20.4500
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
4-hydroxy-6-methyl-2H-pyran-2-one
2-hydroxy-6-methyl-4H-pyran-4-one
 hydroxy-6-methylpyran-2-one
4H-pyran-4-one, 2-hydroxy-6-methyl-
 triacetic acid lactone
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Triacetic acid lactone production in industrial Saccharomyces yeast strains.
PubMed: Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: urinary organic acid profiles and expanded spectrum of mutations.
PubMed: Engineering catalyst microenvironments for metal-catalyzed hydrogenation of biologically derived platform chemicals.
PubMed: Metabolic engineering of Saccharomyces cerevisiae for the production of triacetic acid lactone.
PubMed: k-OptForce: integrating kinetics with flux balance analysis for strain design.
PubMed: Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter.
PubMed: Mechanistic insights into ring-opening and decarboxylation of 2-pyrones in liquid water and tetrahydrofuran.
PubMed: Polyketide derivatives active against Botrytis cinerea in Gerbera hybrida.
PubMed: Synthesis and biological evaluation of (+/-)-dinemasone C and analogues.
PubMed: Synthesis and in-vitro cytotoxic evaluation of novel pyridazin-4-one derivatives.
PubMed: Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa.
PubMed: Convenient replacement of the hydroxy by an amino group in 4 hydroxycoumarin and 4-hydroxy-6-methyl-2-pyrone under microwave irradiation.
PubMed: Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase.
PubMed: Microbial synthesis of triacetic acid lactone.
PubMed: A unique highly oxygenated pyrano[4,3-c][2]benzopyran-1,6-dione derivative with antioxidant and cytotoxic activities from the fungus Phellinus igniarius.
PubMed: Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo.
PubMed: Direct asymmetric Michael reactions of cyclic 1,3-dicarbonyl compounds and enamines catalyzed by chiral bisoxazoline-copper(II) complexes.
PubMed: Aromatic and pyrone polyketides synthesized by a stilbene synthase from Rheum tataricum.
PubMed: Deoxygenation of polyhydroxybenzenes: an alternative strategy for the benzene-free synthesis of aromatic chemicals.
PubMed: Pyrone and pyridone compounds in the liquid culture of Physisporinus sanguinolentus.
PubMed: Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase.
PubMed: A facile and convenient synthesis of 3-alkylamino-5-arylthiophenes with a variety of substituents at C-2 and studies of reaction mechanisms
PubMed: Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot.
PubMed: Dissociation of dimeric 6-hydroxymellein synthase, a polyketide biosynthetic enzyme in carrot cell extracts, with loss of keto-reducing activity.
PubMed: Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum.
PubMed: Derailment product in NADPH-dependent synthesis of a dihydroisocoumarin 6-hydroxymellein by elicitor-treated carrot cell extracts.
PubMed: Decarboxylation of malonyl-CoA by lactating bovine mammary fatty acid synthase.
PubMed: Evidence that the coenzyme A requirement for avian fatty acid synthase is not for the termination reaction.
PubMed: Synthesis of acetoacetyl-CoA by bovine mammary fatty acid synthase.
PubMed: Kinetic analysis of the malonyl coenzyme A decarboxylation and the condensation reaction of fatty acid synthesis. Application to the study of malonyl coenzyme A inactivated chicken liver fatty acid synthetase.
PubMed: Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.
PubMed: Fatty acid synthetase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from pigeon liver.
PubMed: Further characterization and cellular localization of an ATP: triacetic acid lactone lyase in pigeon liver.
PubMed: ATP-dependent enzymic splitting of mesitene lactone and triacetic acid lactone.
PubMed: Triacetic acid lactone, a derailment product of fatty acid biosynthesis.
PubMed: Synthesis of triacetic acid lactone by the pigeon liver fatty acid synthetase complex.
PubMed: The isolation of triacetic acid lactone from cultures of Penicillium patulum.
PubMed: Enzymatic degradation of triacetic acid lactone determined by a spectrophotometric method.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2021 Perflavory ™ Disclaimer Privacy Policy