4-chromanone
4H-1-benzopyran-4-one, 2,3-dihydro-
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
      Facebook
      Twitter
      Linkedin
      Blog
      Get the App!
      Product(s):
      491-37-2 4-chromanone 95%
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
      Facebook
      Twitter
      Instagram
      Linkedin
      Product(s):
      C1175 4-Chromanone >98.0%(GC)
       
Synonyms   Articles   Notes   Search
CAS Number: 491-37-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 207-736-3
Nikkaji Web: J11.757I
Beilstein Number: 124652
MDL: MFCD00006840
XlogP3-AA: 1.40 (est)
Molecular Weight: 148.16116000
Formula: C9 H8 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Refractive Index: 1.57500 @  20.00 °C.
Melting Point: 36.50 °C. @ 760.00 mm Hg
Boiling Point: 253.20 °C. @ 760.00 mm Hg (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 1.990 (est)
Soluble in:
 water, 3060 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
BOC Sciences
For experimental / research use only.
4-chromanone 95%
ExtraSynthese
For experimental / research use only.
4-Chromanone
Santa Cruz Biotechnology
For experimental / research use only.
4-Chromanone
Sigma-Aldrich: Aldrich
For experimental / research use only.
4-Chromanone 97%
TCI AMERICA
For experimental / research use only.
4-Chromanone >98.0%(GC)
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  2647 mg/kg
SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0540641

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for 4-chromanone usage levels up to:
 not for fragrance use.
 
Recommendation for 4-chromanone flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 491-37-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 68110
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 2,3-dihydrochromen-4-one
Chemidplus: 0000491372
RTECS: DJ2981225 for cas# 491-37-2
Synonyms   Articles   Notes   Search   Top
References:
 2,3-dihydrochromen-4-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 68110
Pubchem (sid): 135023981
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2932.99.9090
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
4H-1-benzopyran-4-one, 2,3-dihydro-
 chroman-4-one
2,3-dihydrochromen-4-one
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin a and derivatives.
PubMed: Design, synthesis and biological evaluation of 4-chromanone derivatives as IKr inhibitors.
PubMed: Synthesis and in vitro cytotoxic activity of novel chalcone-like agents.
PubMed: Prospects for flavonoid and related phytochemicals as nature-inspired treatments for Clostridium difficile infection.
PubMed: Rhodium catalyzed oxidative coupling of salicylaldehydes with diazabicyclic olefins: a one pot strategy involving aldehyde C-H cleavage and π-allyl chemistry towards the synthesis of fused ring chromanones.
PubMed: Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: an in vitro study in HUVECs.
PubMed: 3-Bromo-chroman-4-one.
PubMed: Synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones.
PubMed: Enantiomeric scaffolding of α-tetralone and related scaffolds by EKR (enzymatic kinetic resolution) and stereoselective ketoreduction with ketoreductases.
PubMed: Anti-inflammatory activities of selected synthetic homoisoflavanones.
PubMed: Highly efficient construction of spirocyclic chromanone-pyrrolidines via Cu(I)/TF-BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition.
PubMed: A chromanone alkaloid from Derris ovalifolia stem.
PubMed: Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen.
PubMed: Isolation and immunomodulatory effect of homoisoflavones and flavones from Agave sisalana Perrine ex Engelm.
PubMed: [Chemical constitutents in fermental mycelium of Xylaria nigripes].
PubMed: Apralactone A and a New Stereochemical Class of Curvularins from the Marine-Derived Fungus Curvularia sp.
PubMed: Carbonyl emissions from gasoline and diesel motor vehicles.
PubMed: Bioactive alkenylphenols from Piper obliquum.
PubMed: Protective effect of icariin on DNA against radical-induced oxidative damage.
PubMed: Homoisoflavanones from Pseudoprospero firmifolium of the monotypic tribe Pseudoprospereae (Hyacinthaceae: Hyacinthoideae).
PubMed: (+)-Silybin, a pharmacologically active constituent of Silybum marianum: fragmentation studies by atmospheric pressure chemical ionization quadrupole time-of-flight tandem mass spectrometry.
PubMed: The hydrogenation/transfer hydrogenation network: asymmetric hydrogenation of ketones with chiral eta6-arene/N-Tosylethylenediamine-ruthenium(II) catalysts.
PubMed: Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.
PubMed: Icariin: a special antioxidant to protect linoleic acid against free-radical-induced peroxidation in micelles.
PubMed: Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata.
PubMed: Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants.
PubMed: Binding model construction of antifungal 2-aryl-4-chromanones using CoMFA, CoMSIA, and QSAR analyses.
PubMed: The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis.
PubMed: Concise synthesis of anti-HIV-1 active (+)-inophyllum B and (+)-calanolide A by application of (-)-quinine-catalyzed intramolecular oxo-Michael addition.
PubMed: Crystal structure of the 4-chromanone derivative.
PubMed: In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa.
PubMed: Homoisoflavonoids and xanthones from the tubers of wild and in vitro regenerated Ledebouria graminifolia and cytotoxic activities of some of the homoisoflavonoids.
PubMed: Development of novel pesticides based on phytoalexins: Part 2. Quantitative structure-activity relationships of 2-heteroaryl-4-chromanone derivatives.
PubMed: Flavonoids and stilbenoids with COX-1 and COX-2 inhibitory activity from Dracaena loureiri.
PubMed: Carbanion-induced base-catalyzed synthesis of 1H-isothiochromenes, benzo[c]thiochromenes through ring-transformation reactions of 6-aryl-2H-pyran-2-ones.
PubMed: Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity.
PubMed: Synthesis and pharmacological profile of novel N-substituted N-[5H-[1]benzopyrano[4,3-d]pyrimidin-2-YL]-N-methylglycinamides.
PubMed: Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides.
PubMed: Screening of unsubstituted cyclic compounds as inhibitors of monoamine oxidases.
PubMed: Microbiological transformation of chromone, chromanone, and ring A hydroxyflavones.
PubMed: Cycloaddition of dichloroketene to N,N-disubstituted 3-aminomethylene-5-hydroxy-2,2-dimethyl-7-pentyl-4-chromanone: synthesis of 2H,5H-pyrano[3,2-c][1]benzopyran derivatives.
PubMed: Fragmentation of 3-oximino-4-chromanone.
PubMed: 3-amino-4-chromanone hydrochlorides.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2021 Perflavory ™ Disclaimer Privacy Policy