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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 72.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 315.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 130.00 to 131.00 °C. @ 1.00 mm Hg
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| Flash Point: | 302.00 °F. TCC ( 150.00 °C. )
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| logP (o/w): | 1.980 |
| Soluble in: |
| | alcohol | | | water, 1082 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 520 mg/kg Journal of Medicinal Chemistry. Vol. 14, Pg. 551, 1971.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for 4-benzoyl pyridine usage levels up to: | | | not for fragrance use.
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| Recommendation for 4-benzoyl pyridine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| gamma- | benzoyl pyridine | | 4- | benzoylpyridine | | gamma- | benzoylpyridine | | | ketone, phenyl 4-pyridyl | | | methanone, phenyl-4-pyridinyl- | | | phenyl (4-pyridinyl) methanone | | | phenyl 4-pyridyl ketone | | | phenyl-4-pyridinylmethanone | | | phenyl-pyridin-4-yl-methanone | | | phenyl(4-pyridinyl)methanone | | | phenyl(pyridin-4-yl)methanone | | | pyridine, 4-benzoyl- | | 4- | pyridyl phenyl ketone |
Articles:
| US Patents: | 3,952,024 - Furfurylthioacetone |
| PubMed: | Photoinduced Oxidation of Secondary Alcohols Using 4-Benzoylpyridine as an Oxidant. |
| US Patents: | Certain 2,5-dimethyl-3-thiopyrazines |
| PubMed: | Generation of free oxygen atoms O((3)P) in solution by photolysis of 4-benzoylpyridine N-oxide. |
| PubMed: | Synthesis, structure, spectral, thermal and first-order molecular hyperpolarizability of 4-benzoylpyridine isonicotinyl hydrazone monohydrate single crystals. |
| PubMed: | Two copper(II) complexes with 4-benzoylpyridine ligand: synthesis, crystal structure and luminescent properties. |
| PubMed: | Comparative inhibition of tetrameric carbonyl reductase activity in pig heart cytosol by alkyl 4-pyridyl ketones. |
| PubMed: | S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity. |
| PubMed: | Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct. |
| PubMed: | Stereoselective reduction of 4-benzoylpyridine in the heart of vertebrates. |
| PubMed: | 9,10-phenanthrenequinone, a component of diesel exhaust particles, inhibits the reduction of 4-benzoylpyridine and all-trans-retinal and mediates superoxide formation through its redox cycling in pig heart. |
| PubMed: | Towards the chemical control of molecular packing: syntheses and crystal structures of three trans-[NiL4(NCS)2] complexes. |
| PubMed: | Possible mechanism of superoxide formation through redox cycling of plumbagin in pig heart. |
| PubMed: | Different topologies in three manganese-μ-azido 1D compounds: magnetic behavior and DFT-quantum Monte Carlo calculations. |
| PubMed: | Rhenium-to-benzoylpyridine and rhenium-to-bipyridine MLCT excited states of fac-[Re(Cl)(4-benzoylpyridine)(2)(CO)(3)] and fac-[Re(4-benzoylpyridine)(CO)(3)(bpy)](+): a time-resolved spectroscopic and spectroelectrochemical study. |
| PubMed: | Two new one-dimensional compounds with end-to-end dicyanamide as a bridging ligand: syntheses and structural characterization of trans-[Mn(4-bzpy)2(N(CN)2)2]n and cis-[Mn(Bpy)(N(CN)2)2]n, (4-bzpy = 4-benzoylpyridine; bpy = 2,2'-bipyridyl). |
| PubMed: | Excited-state characteristics of tetracyanidonitridorhenium(V) and -technetium(V) complexes with N-heteroaromatic ligands. |
| PubMed: | Interindividual variability of carbonyl reductase levels in human livers. |
| PubMed: | Involvement of carbonyl reductase in superoxide formation through redox cycling of adrenochrome and 9,10-phenanthrenequinone in pig heart. |
| PubMed: | Inhibitory effects of flavonoids on rabbit heart carbonyl reductase. |
| PubMed: | Purification and catalytic properties of a tetrameric carbonyl reductase from rabbit heart. |
| PubMed: | Immunohistochemical localization and physiological regulation of carbonyl reductase in immature rat ovary. |
| PubMed: | Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode. |
| PubMed: | [Structure and function of peroxisomal tetrameric carbonyl reductase]. |
| PubMed: | Luminescence ranging from red to blue: a series of copper(I)-halide complexes having rhombic {Cu2(mu-X)2} (X = Br and I) units with N-heteroaromatic ligands. |
| PubMed: | Inhibition of rabbit heart carbonyl reductase by fatty acids. |
| PubMed: | Characterization of multiple forms of carbonyl reductase from chicken liver. |
| PubMed: | Effects of antiestrogens on ovarian aldo-keto reductase in relation to ovulation in rats. |
| PubMed: | Regulation of ovarian carbonyl reductase mediated by estrogen receptor in immature rats. |
| PubMed: | Carbonyl reductases from rat testis and vas deferens. Purification, properties and localization. |
| PubMed: | Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1. |
| PubMed: | Inhibition of carbonyl reductase activity in pig heart by alkyl phenyl ketones. |
| PubMed: | Differences in catalytic activity between rat testicular and ovarian carbonyl reductases are due to two amino acids. |
| PubMed: | Characterization of multiple Chinese hamster carbonyl reductases. |
| PubMed: | Pre- and post-ovulatory changes in carbonyl reductase in ovarian follicles and corpora lutea in rats. |
| PubMed: | Carbonyl reductase activity exhibited by pig testicular 20 beta-hydroxysteroid dehydrogenase. |
| PubMed: | Inhibition of pink color development in cooked, uncured ground turkey through the binding of non-pink generating ligands to muscle pigments. |
| PubMed: | Effects of psychotropic drugs on aldo-keto reductase activity in rat ovary and adrenal gland. |
| PubMed: | Purification and characterization of 5 alpha-dihydrotestosterone 3 beta-hydroxysteroid dehydrogenase from mature pig testicular cytosol. |
| PubMed: | Structural requirements for the induction of hepatic microsomal cytochrome P450 by imidazole- and pyridine-containing compounds in rats. |
| PubMed: | Changes and localization of ovarian carbonyl reductase during pseudopregnancy and pregnancy in rats. |
| PubMed: | Physiological role of ovarian carbonyl reductase and effect of antiestrogen on its activity in rats. |
| PubMed: | Kinetic mechanisms in the reduction of aldehydes and ketones catalyzed by rabbit liver aldehyde reductases and hydroxysteroid dehydrogenases. |
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