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benzoic acid, 4-amino-
Notes:
A member of the VITAMIN B COMPLEX. It used to be common in SUNSCREENING AGENTS until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders. a member of the vitamin b complex. it used to be common in sunscreening agents until found to also be a sensitizer. the potassium salt is used therapeutically in fibrotic skin disorders. Listed in the EAFUS Food Additive Database (Jan. 2001) but with no reported use
4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA) is an organic compound with the molecular formula C7H7NO2. PABA is a white crystalline substance that is only slightly soluble in water. It consists of a benzene ring substituted with an amino group and a carboxyl group.; 4-Aminobenzoic acid, para-aminobenzoic acid, or simply PABA, is an organic compound with molecular formula C7H7NO2. PABA is a white crystalline substance that is only slightly soluble in water. It consists of a benzene ring substituted with an amino group and a carboxylic acid.; A member of the vitamin B complex. It used to be a common sunscreening agent until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.; PABA is an essential nutrient for some bacteria and is sometimes called Vitamin Bx. However, PABA is not essential for humans and it varies in its activity from other B vitamins. Although humans lack the ability to synthesize folate from PABA, it is sometimes marketed as an essential nutrient under the premise that it can stimulate intestinal bacteria.; PABA is an essential nutrient for some bacteria and is sometimes called Vitamin Bx. In humans, PABA is normally made by E. coli in the colon and therefore PABA from food is not normally essential to human health. PABA is therefore not officially classified as a vitamin. PABA is an intermediate in bacterial synthesis of folate. Although humans lack the ability to synthesize folate from PABA, that is also normally done by E. coli. PABA is sometimes marketed as an essential nutrient for use whenever normal PABA synthesis by intestinal bacteria is insufficient.
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): PABAUP PABA
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Charkit Chemical Corporation The Specialty Chemical Specialists Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you. about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals. Email: Sales Voice: 203-299-3220 Fax: 203-299-1355 Facebook Twitter Linkedin Latest News Events Blog Products List: View Product(s): AMINOBENZOIC ACID, P-
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GM6679 4-Aminobenzoic acid SDS GM2145 4-Aminobenzoic acid, USP grade
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 01-24300 P-AMINOBENZOIC ACID USP
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): A0269 4-Aminobenzoic Acid >99.0%(HPLC)(T)
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| CAS Number: | 150-13-0 |  3D/inchi
|
| Other(deleted CASRN): | 8014-65-1 | |
| ECHA EINECS - REACH Pre-Reg: | 205-753-0 | |
| FDA UNII: | TL2TJE8QTX | |
| Nikkaji Web: | J5.852A | |
| Beilstein Number: | 0471605 | |
| MDL: | MFCD00007894 | |
| XlogP3: | 0.80 (est) | |
| Molecular Weight: | 137.13819000 | |
| Formula: | C7 H7 N O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: miscellaneous
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA Mainterm (SATF): | 150-13-0 ; P-AMINOBENZOIC ACID |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.37400 @ 25.00 °C. |
| Melting Point: | 188.00 to 189.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 339.00 to 340.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 319.00 °F. TCC ( 159.40 °C. ) (est) |
| logP (o/w): | 0.830 |
| Soluble in: | |
| alcohol | |
| water, 6110 mg/L @ 30 °C (exp) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data2 |
| CosIng: | cosmetic data |
| Cosmetic Uses: |
not used anymore |
Suppliers:
| AIDP |
| PABA Para amino benzoic acid, 4-Aminobenzoic acid 98.5%-101.5% |
| American International Chemical, LLC. |
| PABA |
| BOC Sciences |
| For experimental / research use only. |
| Tetracaine HCl Impurity A 95%
Odor: characteristic Use: 4-Aminobenzoic Acid, also called as PABA, was used as sunscreening agent at the past due to its UV absorption and antifibrotic properties. |
| Charkit Chemical |
| AMINOBENZOIC ACID, P- |
| EMD Millipore |
| For experimental / research use only. |
| 4-Aminobenzoic acid |
| Glentham Life Sciences |
| 4-Aminobenzoic acid, USP grade |
| Glentham Life Sciences |
| 4-Aminobenzoic acid |
| Indis NV |
| For experimental / research use only. |
| PABA (Para Amino Benzoic Acid) |
| Penta International |
| P-AMINOBENZOIC ACID USP |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| p-Aminobenzoic acid 99% |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| p-Aminobenzoic acid ReagentPlus®, 99% |
| TCI AMERICA |
| For experimental / research use only. |
| 4-Aminobenzoic Acid >99.0%(HPLC)(T) |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 43 - May cause sensitisation by skin contact. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 > 6000 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 49, Pg. 184, 1942. intraperitoneal-rat LD50 > 3450 mg/kg Bollettino Chimico Farmaceutico. Vol. 112, Pg. 53, 1973. oral-rabbit LD50 1830 mg/kg Bollettino Chimico Farmaceutico. Vol. 112, Pg. 53, 1973. intravenous-rabbit LD50 2000 mg/kg Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 1, Pg. 71, 1942. oral-mouse LD50 2850 mg/kg BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Proceedings of the Society for Experimental Biology and Medicine. Vol. 49, Pg. 184, 1942. oral-dog LD50 1000 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 49, Pg. 184, 1942. oral-rabbit LD50 1830 mg/kg Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 10, Pg. 289, 1951. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | miscellaneous | ||
| Recommendation for para-anthranilic acid usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for para-anthranilic acid flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 150-13-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 978 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 4-aminobenzoic acid | |
| Chemidplus: | 0000150130 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | DG1400000 for cas# 150-13-0 |
References:
| 4-aminobenzoic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 150-13-0 |
| Pubchem (cid): | 978 |
| Pubchem (sid): | 134973070 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00568 |
| HMDB (The Human Metabolome Database): | HMDB01392 |
| FooDB: | FDB001037 |
| YMDB (Yeast Metabolome Database): | YMDB00493 |
| Export Tariff Code: | 2922.49.1000 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: sunscreens are available in a variety of dosage forms and formulations. ? because these formulations frequently change and the manufacturers often are reluctant to reveal specific ingredients in their formulations, a listing of commercially available sunscreens is not included in this monograph. technical, national formulary capsules and tablets (as the potassium salt), 500 mg; packets (as the potassium salt) 2 g; powder topical cream, aminobenzoic acid 4% and titanium dioxide 12%, solar spf 15 (spf 15), doak; lipstick, aminobenzoic acid 5% and red pertolatum, rvpaba (spf 10), elder; lotion, aminobenzoic acid 5%, oxybenzone 3%, and padimate o 5%, presun 15 sunscreen lotion (with sd alcohol 40 58%; spf 15), westwood-squibb. | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| u.v. absorbers |
Occurrence (nature, food, other): note
| not found in nature | |
| pineapple fruit Search Trop Picture | |
| rice plant Search Trop Picture |
Synonyms:
| ABEE | |
| actipol | |
| 4- | amino benzoic acid |
| p- | amino benzoic acid |
| 1- | amino-4-carboxybenzene |
| p- | amino-benzoic acid |
| 4- | aminobenzoic acid |
| gamma- | aminobenzoic acid |
| p- | aminobenzoic acid |
| para- | aminobenzoic acid |
| 4- | aminobenzoicacid |
| aniline-4-carboxylic acid | |
| p- | anthranilic acid |
| anti-gray-hair factor | |
| anticantic vitamin | |
| antichromotrichia factor | |
| benzoic acid, 4-amino- | |
| 4- | carboxyaniline |
| p- | carboxyaniline |
| para- | carboxyaniline |
| p- | carboxyphenyl amine |
| para- | carboxyphenyl amine |
| 4- | carboxyphenylamine |
| PABA | |
| trochromogenic factor |