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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 43.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 268.20 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.008000 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. )
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| logP (o/w): | 1.740 |
| Soluble in: |
| | water, 2320 mg/L @ 25 °C (exp) | | | water, 998.2 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 600 mg/kg BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Annales des Falsifications et de l'Expertise Chimique. Vol. 76(815), Pg. 65, 1983.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for 2-nitrobenzaldehyde usage levels up to: | | | not for fragrance use.
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| Recommendation for 2-nitrobenzaldehyde flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzaldehyde, 2-nitro- | | | benzaldehyde, o-nitro- | | 2- | formylnitrobenzene | | 2- | nitro-benzaldehyde | | o- | nitrobenzaldehyde | | ortho- | nitrobenzaldehyde |
Articles:
| PubMed: | Determination of nitrofuran and chloramphenicol residues by high resolution mass spectrometry versus tandem quadrupole mass spectrometry. |
| PubMed: | Palladium-catalyzed one pot 2-arylquinazoline formation via hydrogen-transfer strategy. |
| PubMed: | Electrocatalytic reduction of ortho nitrobenzaldehyde using modified aluminum electrode and its determination. |
| PubMed: | Regioselective synthesis of 2H-indazoles using a mild, one-pot condensation-Cadogan reductive cyclization. |
| PubMed: | In vitro and in silico antimalarial activity of 2-(2-hydrazinyl)thiazole derivatives. |
| PubMed: | The synthesis and the biological evaluation of new thiazolidin-4-one derivatives containing a xanthine moiety. |
| PubMed: | Identification and characterization of four bacterial strains isolated from a bioaugmented sequencing batch reactor. |
| PubMed: | [Determination of metabolite residues of nitrofuran antibiotics in aquatic products by liquid chromatography-tandem mass spectrometry]. |
| PubMed: | Critical practical aspects in the application of liquid chromatography-mass spectrometric studies for the characterization of impurities and degradation products. |
| PubMed: | Photoswitching of enzyme activity by laser-induced pH-jump. |
| PubMed: | Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling. |
| PubMed: | A photoinduced nanoparticle separation in microchannels via pH-sensitive surface traps. |
| PubMed: | NHC-promoted asymmetric β-lactone formation from arylalkylketenes and electron-deficient benzaldehydes or pyridinecarboxaldehydes. |
| PubMed: | Development and validation of a new method for determining nitrofuran metabolites in bovine urine using liquid chromatography - tandem mass spectrometry. |
| PubMed: | Development of a competitive ELISA for the detection of a furaltadone marker residue, 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), in cultured fish samples. |
| PubMed: | Cloning, expression, purification, and characterization of a novel single-chain variable fragment antibody against the 2-nitrobenzaldehyde derivative of a furaltadone metabolite in Escherichia coli. |
| PubMed: | Synthesis, characterization and biological activity of transition metal complexes with Schiff bases derived from 2-nitrobenzaldehyde with glycine and methionine. |
| PubMed: | Microwave-assisted synthesis and bioevaluation of some semicarbazones. |
| PubMed: | InCl3-driven regioselective synthesis of functionalized/annulated quinolines: scope and limitations. |
| PubMed: | Biotreatment of o-nitrobenzaldehyde manufacturing wastewater and changes in activated sludge flocs in a sequencing batch reactor. |
| PubMed: | Light-induced spatial control of pH-jump reaction at smart gel interface. |
| PubMed: | A non-adiabatic quantum-classical dynamics study of the intramolecular excited state hydrogen transfer in ortho-nitrobenzaldehyde. |
| PubMed: | Ultrafast irreversible phototautomerization of o-nitrobenzaldehyde. |
| PubMed: | High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde. |
| PubMed: | Detection of banned nitrofuran metabolites in animal plasma samples using UHPLC-MS/MS. |
| PubMed: | Femtosecond spectroscopy on the photochemistry of ortho-nitrotoluene. |
| PubMed: | Fluorescence and solvent-dependent phosphorescence studies of o-nitrobenzaldehyde: a combined experimental and theoretical investigation. |
| PubMed: | A one-step synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid esters from o-nitrobenzaldehydes. |
| PubMed: | Oriented synthesis and in vitro anticancer activity of biquinazoline-2,2'-diones. |
| PubMed: | Impact of vibrational excitation on the kinetics of a nascent ketene. |
| PubMed: | Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes. |
| PubMed: | Bioaugmentation of a sequencing batch reactor with Pseudomonas putida ONBA-17, and its impact on reactor bacterial communities. |
| PubMed: | "Catalysis in a tea bag": synthesis, catalytic performance and recycling of dendrimer-immobilised bis- and trisoxazoline copper catalysts. |
| PubMed: | LED-array photocalorimetry: instrument design and application to photostability of nifedipine. |
| PubMed: | The ketene intermediate in the photochemistry of ortho-nitrobenzaldehyde. |
| PubMed: | [Determination of nitrofuran metabolites residues in animal tissues by LC-MS/MS method]. |
| PubMed: | Coordination compounds based on 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid. |
| PubMed: | Synthesis, infrared spectra and thermal studies of Zn(II), Cd(II) and Hg(II) complexes with 2-aminobenzaldehyde phenylhydrazone "nitrin" ligand. |
| PubMed: | Development and validation of an analytical method for the determination of semicarbazide in fresh egg and in egg powder based on the use of liquid chromatography tandem mass spectrometry. |
| PubMed: | Reductive heterocyclizations via indium-iodine-promoted conversion of 2-nitroaryl imines or 2-nitroarenes to 2,3-diaryl-substituted indazoles. |
| PubMed: | Development of an isothermal heat-conduction photocalorimeter. |
| PubMed: | Determination of nitrofuran residues in milk of dairy cows using liquid chromatography-tandem mass spectrometry. |
| PubMed: | Determination and confirmation of nitrofuran residues in honey using LC-MS/MS. |
| PubMed: | Determination of semicarbazide in fresh egg and whole egg powder by liquid chromatography/tandem mass spectrometry: interlaboratory validation study. |
| PubMed: | A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes. |
| PubMed: | Isolation and characterization of Pseudomonas sp. strain ONBA-17 degrading o-nitriobenzaldehyde. |
| PubMed: | Advantages of LC-MS-MS compared to LC-MS for the determination of nitrofuran residues in honey. |
| PubMed: | pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound. |
| PubMed: | Simultaneous separation of nitrofuran antibiotics and their metabolites by using micellar electrokinetic capillary chromatography. |
| PubMed: | A new member of the aldo-keto reductase family from the plant pathogen Xylella fastidiosa. |
| PubMed: | Determination of semicarbazide in baby food by liquid chromatography/tandem mass spectrometry: interlaboratory validation study. |
| PubMed: | Semicarbazide in Canadian bakery products. |
| PubMed: | Four nitrobenzaldehyde isonicotinoylhydrazones at 120 K: four different supramolecular structures in two and three dimensions. |
| PubMed: | The photochemistry of o-nitrobenzaldehyde as seen by femtosecond vibrational spectroscopy. |
| PubMed: | Liquid chromatography-tandem mass spectrometry for the determination of protein-bound residues in shrimp dosed with nitrofurans. |
| PubMed: | Three isomeric (E)-nitrobenzaldehyde nitrophenylhydrazones: chains of rings in isomorphous (E)-2-nitrobenzaldehyde 3-nitrophenylhydrazone and (E)-3-nitrobenzaldehyde 2-nitrophenylhydrazone, and centrosymmetric dimers in (E)-4-nitrobenzaldehyde 2-nitrophenylhydrazone. |
| PubMed: | Effects of 4,5-dimethoxy groups on the time-resolved photoconversion of 2-nitrobenzyl alcohols and 2-nitrobenzaldehyde into nitroso derivatives. |
| PubMed: | Analysis of semicarbazide in baby food by liquid chromatography tandem mass spectrometry (LC-MS-MS)--in-house method validation. |
| PubMed: | The determination of semicarbazide (N-aminourea) in commercial bread products by liquid chromatography-mass spectrometry. |
| PubMed: | Determination of nifursol metabolites in poultry muscle and liver tissue. Development and validation of a confirmatory method. |
| PubMed: | Quantitative determination of four nitrofuran metabolites in meat by isotope dilution liquid chromatography-electrospray ionisation-tandem mass spectrometry. |
| PubMed: | Analysis of nifursol residues in turkey and chicken meat using liquid chromatography-tandem mass spectrometry. |
| PubMed: | [Benzo[h][1 ,6]naphthyridines from dimethyl 1,2-dihydro-2-(2-nitrophenyl)-pyridine-3,5-dicarboxylate]. |
| PubMed: | Hydrogen-bonded sheets in (E)-2-nitrobenzaldehyde 4-nitrophenylhydrazone and a hydrogen-bonded framework structure in (E)-4-nitrobenzaldehyde 4-nitrophenylhydrazone. |
| PubMed: | Photodegradation of organic pollutants on the spruce needle wax surface under laboratory conditions. |
| PubMed: | Semicarbazide formation in azodicarbonamide-treated flour: a model study. |
| PubMed: | Hydrogen-bonded dimers in 2-nitrobenzaldehyde hydrazone and a three-dimensional hydrogen-bonded framework in 3-nitrobenzaldehyde hydrazone. |
| PubMed: | Analysis of matrix-bound nitrofuran residues in worldwide-originated honeys by isotope dilution high-performance liquid chromatography-tandem mass spectrometry. |
| PubMed: | Solid-phase synthesis of tetrahydro-1,4-benzodiazepine-2-one derivatives as a beta-turn peptidomimetic library. |
| PubMed: | Semicarbazide is a minor thermal decomposition product of azodicarbonamide used in the gaskets of certain food jars. |
| PubMed: | [Benzo[c][2,7]naphthyridines from 2,6-dinor-nifedipine and its dimethyl 2,5-dicarboxylate isomer]. |
| PubMed: | A one pot synthesis and evaluation of 13-oxo-quino[3,4-b]carbazol-N-oxides as antimicrobial agents. |
| PubMed: | Solid phase synthesis of 2-aminoquinazoline-based compounds. |
| PubMed: | Preparation of stable isotope-labeled 2-nitrobenzaldehyde derivatives of four metabolites of nitrofuran antibiotics and their comprehensive characterization by UV, MS, and NMR techniques. |
| PubMed: | Deprotonation yields, pKa, and aci-nitro decay rates in some substituted o-nitrobenzaldehydes. |
| PubMed: | Analysis of cigarette mainstream smoke for 1,1-dimethylhydrazine and vinyl acetate by gas chromatography-mass spectrometry. |
| PubMed: | Characterization of recombinant YakC of Schizosaccharomyces pombe showing YakC defines a new family of aldo-keto reductases. |
| PubMed: | Studies on quinones. Part 37. Synthesis and biological activity of o-aminoester functionalised benzo- and naphtho[2,3-b]thiophenequinones. |
| PubMed: | Use of solid phase extraction for the isolation and clean-up of a derivatised furazolidone metabolite from animal tissues. |
| PubMed: | New insights into the acid-promoted reaction of caffeic acid and its esters with nitrite: decarboxylation drives chain nitrosation pathways toward novel oxime derivatives and oxidation/fragmentation products thereof. |
| PubMed: | Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography-tandem mass spectrometry. |
| PubMed: | 2-Nitrobenzaldehyde: a convenient UV-A and UV-B chemical actinometer for drug photostability testing. |
| PubMed: | Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members. |
| PubMed: | Purification, molecular cloning, and catalytic activity of Schizosaccharomyces pombe pyridoxal reductase. A possible additional family in the aldo-keto reductase superfamily. |
| PubMed: | Determination of the furazolidone metabolite, 3-amino-2-oxazolidinone, in porcine tissues using liquid chromatography-thermospray mass spectrometry and the occurrence of residues in pigs produced in Northern Ireland. |
| PubMed: | Analysis of protein-bound metabolites of furazolidone and furaltadone in pig liver by high-performance liquid chromatography and liquid chromatography-mass spectrometry. |
| PubMed: | The free radical site in pea seedling copper amine oxidase probed by resonance Raman spectroscopy and generated by photolysis of caged substrate. |
| PubMed: | Improved gas chromatographic method for determination of daminozide by alkaline hydrolysis and 2-nitrobenzaldehyde derivatization and survey results of daminozide in agricultural products. |
| PubMed: | No-carrier-added regioselective preparation of 6-[18F]fluoro-L-dopa. |
| PubMed: | Proton concentration jumps and generation of transmembrane pH-gradients by photolysis of 4-formyl-6-methoxy-3-nitrophenoxyacetic acid. |
| PubMed: | Comparative metabolism of nitroaromatic compounds in freshwater, brackish water and marine decapod crustaceans. |
| PubMed: | New method for the determination of 1,1-dimethylhydrazine residues in apples and peaches. |
| PubMed: | [Toxic substances sought in sneezing powders]. |
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