| PubMed: | UHPLC-Q-Orbitrap-HRMS-based global metabolomics reveal metabolome modifications in plasma of young women after cranberry juice consumption. |
| PubMed: | Quantitative determination of five metabolites of aspirin by UHPLC-MS/MS coupled with enzymatic reaction and its application to evaluate the effects of aspirin dosage on the metabolic profile. |
| PubMed: | Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid. |
| PubMed: | Diverse Data Sets Can Yield Reliable Information through Mechanistic Modeling: Salicylic Acid Clearance. |
| PubMed: | Fecal metabolomics: assay performance and association with colorectal cancer. |
| PubMed: | Second-order multivariate models for the processing of standard-addition synchronous fluorescence-pH data. Application to the analysis of salicylic acid and its major metabolite in human urine. |
| PubMed: | Aspirin metabolites are GPR35 agonists. |
| PubMed: | Salicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties. |
| PubMed: | Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site. |
| PubMed: | Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice. |
| PubMed: | Serum albumin complexation of acetylsalicylic acid metabolites. |
| PubMed: | Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers. |
| PubMed: | Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid. |
| PubMed: | [Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs]. |
| PubMed: | Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. |
| PubMed: | Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice. |
| PubMed: | Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites. |
| PubMed: | Simultaneous determination of gentisic, salicyluric and salicylic acid in human plasma using solid-phase extraction, liquid chromatography and electrospray ionization mass spectrometry. |
| PubMed: | Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt. |
| PubMed: | Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases. |
| PubMed: | Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin. |
| PubMed: | First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine. |
| PubMed: | Lack of pharmacokinetic interaction between the oral anti-influenza prodrug oseltamivir and aspirin. |
| PubMed: | Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs. |
| PubMed: | Pharmacokinetics of salicin after oral administration of a standardised willow bark extract. |
| PubMed: | Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection. |
| PubMed: | Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid. |
| PubMed: | Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. |
| PubMed: | Characterization of a renal medium chain acyl-CoA synthetase responsible for glycine conjugation in mouse kidney mitochondria. |
| PubMed: | Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. |
| PubMed: | Influence of nutritional status on the pharmacokinetics of acetylsalicylic acid and its metabolites in children with autoimmune disease. |
| PubMed: | Assay of acetylsalicylic acid and three of its metabolites in human plasma and urine using non-aqueous capillary electrophoresis with reversed electroosmotic flow. |
| PubMed: | A highly sensitive HPLC method for the simultaneous determination of acetylsalicylic, salicylic and salicyluric acids in biologic fluids: pharmacokinetic, metabolic and monitoring implications. |
| PubMed: | Laser induced resonance energy transfer--a novel approach towards achieving high sensitivity in capillary electrophoresis. I. Clinical diagnostic application. |
| PubMed: | Pharmacokinetics of nitazoxanide after single oral dose administration in 6 healthy volunteers. |
| PubMed: | Direct analysis of salicylic acid, salicyl acyl glucuronide, salicyluric acid and gentisic acid in human plasma and urine by high-performance liquid chromatography. |
| PubMed: | Transdermal delivery of drugs with differing lipophilicities using azone analogs as dermal penetration enhancers. |
| PubMed: | Influence of acetylsalicylic acid and metabolites on DU-145 prostatic cancer cell proliferation. |
| PubMed: | Salicylate poisoning: two-dimensional J-resolved NMR urinalysis. |
| PubMed: | Pharmacokinetics of acetylsalicylic acid and its metabolites at low doses: a compartmental modeling. |
| PubMed: | Zero-crossing first and second derivative synchronous fluorescence spectroscopic determination of aspirin metabolites in urine. |
| PubMed: | Effect of urinary pH on the pharmacokinetics of salicylic acid, with its glycine and glucuronide conjugates in human. |
| PubMed: | Mechanism and elimination of aspirin-induced interference in Emit II d.a.u. assays. |
| PubMed: | The absence of a pharmacokinetic interaction between aspirin and the angiotensin-converting enzyme inhibitor benazepril in healthy volunteers. |
| PubMed: | Direct gradient reversed-phase high-performance liquid chromatographic determination of salicylic acid, with the corresponding glycine and glucuronide conjugates in human plasma and urine. |
| PubMed: | Effects of nocloprost clathrate on absorption of acetylsalicylic acid. |
| PubMed: | Disposition of salicylic acid in malnourished Ethiopian children after single oral dose. |
| PubMed: | Transport of aspirin and its metabolites through human erythrocyte membrane. |
| PubMed: | Simultaneous high-performance liquid chromatographic determination of salicylates in whole blood, plasma and isolated erythrocytes. |
| PubMed: | The effect of antacid on aspirin pharmacokinetics in healthy Thai volunteers. |
| PubMed: | Decrease of gastrointestinal mucosal damage by salicyluric acid compared with salicylic acid in rabbits. |
| PubMed: | Novel direct high-performance liquid chromatographic method for determination of salicylate glucuronide conjugates in human urine. |
| PubMed: | The influence of age on salicylate pharmacokinetics in humans. |
| PubMed: | Pharmacokinetics and elimination of salicylic acid in rabbits. |
| PubMed: | Salicylic acid disposition in children with rheumatoid arthritis. |
| PubMed: | Depletion of plasma glycine and effect of glycine by mouth on salicylate metabolism during aspirin overdose. |
| PubMed: | Isolated perfused rat kidney as a tool in the investigation of renal handling and effects of nonsteroidal antiinflammatory drugs. |
| PubMed: | Pharmacokinetics and protein binding of salicylate metabolites in rats. |
| PubMed: | Elimination of salicylic acid in goats and cattle. |
| PubMed: | Comparative metabolism of high doses of aspirin in man and rat. |
| PubMed: | Effect of pretreatment with antibiotics on the hydrolysis of salicyluric acid in rabbit intestinal microorganisms. |
| PubMed: | Determination of salicylic acid and its metabolites in urine by derivative synchronous spectrofluorimetry. |
| PubMed: | Metabolism of aspirin after therapeutic and toxic doses. |
| PubMed: | Effects of dietary sodium selenite supplementation on salicylate-induced embryo- and fetotoxicity in the rat. |
| PubMed: | Sex differences in salicylic acid metabolism in streptozotocin induced diabetes in rats. |
| PubMed: | Renal handling of salicyluric acid in the isolated perfused rat kidney: evidence for accumulation in tubular cells. |
| PubMed: | Drug interactions involving aspirin (acetylsalicylic acid) and salicylic acid. |
| PubMed: | Effect of fasting on the hydrolysis of salicyluric acid in rabbit intestinal microorganisms. |
| PubMed: | Sustained blood concentration of salicylic acid following rectal administration of salicyluric acid in dogs. |
| PubMed: | Protein binding of salicylic and salicyluric acid in serum from malnourished children: the influence of albumin, competitive binding and non-esterified fatty acids. |
| PubMed: | Effects of subchronic parathion administration on sodium salicylate excretion kinetics in female rats. |
| PubMed: | Inhibitory effect of free fatty acids on plasma protein binding of disopyramide in haemodialysis patients. |
| PubMed: | Simultaneous determination of salicylic and salicyluric acids in urine by first-derivative synchronous fluorescence spectroscopy. |
| PubMed: | Salicylurate-hydrolyzing enzyme from intestinal bacterium in rabbit: purification and characterization. |
| PubMed: | The effect of 2-hydroxybenzoylglycine on bilirubin-albumin binding. |
| PubMed: | Hydrolysis of salicyluric acid in intestinal microorganisms and prolonged blood concentration of salicylic acid following rectal administration of salicyluric acid in rats. |
| PubMed: | Possible genetic influence on conjugate formation in salicylic acid metabolism. |
| PubMed: | Sulfate homeostasis. I. Effect of salicylic acid and its metabolites on inorganic sulfate in rats. |
| PubMed: | Interactions of m-xylene and aspirin metabolism in man. |
| PubMed: | Further studies on the hydrolysis of salicyluric acid in intestinal microorganisms and prolonged blood concentration of salicylic acid following rectal administration of salicyluric acid in rabbits. |
| PubMed: | Contributions of hippurate, indoxyl sulfate, and o-hydroxyhippurate to impaired ligand binding by plasma in azotemic humans. |
| PubMed: | Demonstration of 2-hydroxybenzoylglycine as a drug binding inhibitor in newborn infants. |
| PubMed: | Physiologically based pharmacokinetic model for the renal clearance of salicyluric acid and the interaction with phenolsulfonphthalein in the dog. |
| PubMed: | Physiologically based pharmacokinetic model for the renal clearance of phenolsulfonphthalein and the interaction with probenecid and salicyluric acid in the dog. |
| PubMed: | Disposition of aspirin and its metabolites in the semen of man. |
| PubMed: | Effect of food on the absorption of enteric-coated aspirin: correlation with gastric residence time. |
| PubMed: | Salicyl phenolic glucuronide pharmacokinetics in patients with rheumatoid arthritis. |
| PubMed: | A new HPLC analytical method for o-hydroxyhippuric acid in uremic serum. |
| PubMed: | Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids. |
| PubMed: | Prolonged blood concentration of salicylic acid following the simultaneous oral administration of salicylic acid and salicyluric acid in rabbits. |
| PubMed: | Salicylate metabolism: effects of age and sex in adults. |
| PubMed: | Salicylate metabolites in synovial fluid. |
| PubMed: | The metabolism of aspirin in man: a population study. |
| PubMed: | Sex differences in salicylic acid metabolism in Nigerian subjects. |
| PubMed: | Evaluation of a potential drug interaction between sucralfate and aspirin. |
| PubMed: | A method for separation of middle molecules by high performance liquid chromatography: application in studies of glucuronyl-o-hydroxyhippurate in normal and uremic subjects. |
| PubMed: | Acetylsalicylic acid metabolites in blood and urine after plain and enteric-coated tablets. |
| PubMed: | Protein binding of ceftriaxone: comparison of three techniques of determination and the effect of 2-hydroxybenzoylglycine, a drug-binding inhibitor in uremia. |
| PubMed: | Effect of exercise and heat exposure on percutaneous absorption of methyl salicylate. |
| PubMed: | Direct measurement of salicylphenolic glucuronide in human urine. |
| PubMed: | Profiling of endogenous ligand solutes that bind to serum proteins in sera of patients with uremia. |
| PubMed: | Hydrolysis of salicyluric acid in rabbit intestinal microorganisms. |
| PubMed: | The effect of age on salicylate-induced nephrotoxicity in male rats. |
| PubMed: | Effect of probenecid on the renal tubular secretion of salicyluric acid by the isolated perfused rat kidney. |
| PubMed: | The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites. |
| PubMed: | Plasma and synovial fluid gentisate in patients receiving salicylate therapy. |
| PubMed: | Plasma and synovial fluid concentrations of salicylic acid and its metabolites in patients with joint effusions. |
| PubMed: | [The bioavailability of combination preparations of acetylsalicylic acid and codeine phosphate]. |
| PubMed: | Plasma salicylate levels and platelet function after acute and chronic administration of slow-release acetylsalicylic acid (Monobeltin). |
| PubMed: | A compound from uremic plasma and from normal urine isolated by liquid chromatography and identified by nuclear magnetic resonance. |
| PubMed: | Community Surveillance Study--perceived response of rheumatoid arthritis patients to NSAIDs. |
| PubMed: | Improved method for the determination of aspirin and its metabolites in biological fluids by high-performance liquid chromatography: applications to human and animal studies. |
| PubMed: | Metabolism of salsalate in normal subjects. |
| PubMed: | Rapid and sensitive determination of acetylsalicylic acid and its metabolites using reversed-phase high-performance liquid chromatography. |
| PubMed: | Pharmacokinetic pilot study with imidazole 2-hydroxybenzoate using new analytical methods. |
| PubMed: | Zomepirac--aspirin interactions in man. |
| PubMed: | Comparative aspirin absorption kinetics after administration of sodium- and potassium-containing buffered solutions. |
| PubMed: | High-performance liquid chromatographic determination of aspirin and its metabolites in plasma and urine. |
| PubMed: | Simultaneous kinetic modelling of plasma levels and urinary excretion of salicyluric acid, and the influence of probenecid. |
| PubMed: | Isolation and chemical characterization of 2-hydroxybenzoylglycine as a drug binding inhibitor in uremia. |
| PubMed: | Induction of salicyluric acid formation in rheumatoid arthritis patients treated with salicylates. |
| PubMed: | Determination of acetylsalicylic acid and metabolites in biological fluids by high-performance liquid chromatography. |
| PubMed: | Studies on simultaneous determination of acetaminophen, salicylic acid and salicyluric acid in biological fluids by high performance liquid chromatography. |
| PubMed: | A method for high-performance liquid chromatographic screening of UV-positive components in urine eluate from sephadex G-10 and modifications for determination of urinary salicylic, salicyluric and gentisic acids. |
| PubMed: | Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine. |
| PubMed: | [Transdermal salicylate absorption following epidermal application of an analgesic / antiphlogistic ointment and gel formulation (author's transl)]. |
| PubMed: | Determination of aspirin and its major metabolites in plasma by high-performance liquid chromatography without solvent extraction. |
| PubMed: | Formation of methyl ester of salicyluric acid during quantitation of salicyluric acid in urine by high-pressure liquid chromatography. |
| PubMed: | Salicylate metabolite kinetics after several salicylates. |
| PubMed: | Characterization of a double conjugate in uremic body fluids. |
| PubMed: | Kinetics of aspirin, salicylic acid, and salicyluric acid following oral administration of aspirin as a tablet and two buffered solutions. |
| PubMed: | Comparative plasma salicylate and urine salicylurate levels following administration of aspirin, magnesium salicylate, and choline magnesium trisalicylate. |
| PubMed: | High-pressure liquid chromatography analysis of salicylic acid, salicyluric acid, and gentisic acid in biological matrixes. |
| PubMed: | Metabolism of salicylic acid in the isolated perfused rat kidney. Interconversion of salicyluric and salicyclic acids. |
| PubMed: | Metabolism of salicylate during chronic aspirin therapy. |
| PubMed: | Renal concentration gradients of salicylic acid and its metabolic congeners in the dog. |
| PubMed: | Salicylate metabolism in twins. Evidence suggesting a genetic influence and induction of salicylurate formation. |
| PubMed: | Correlation of plateau serum salicylate level with rate of salicylate metabolism. |
| PubMed: | Fetal acquisition and neonatal elimination of a large amount of salicylate. Study of a neonate whose mother regularly took therapeutic doses of aspirin during pregnancy. |
| PubMed: | Kinetics of salicylate elimination by anephric patients. |
| PubMed: | Enzymatic conversion of salicylate to salicylurate. |
| PubMed: | Capacity-limited salicylurate formation during prolonged administration of aspirin to healthy human subjects. |
| PubMed: | SALICYLURATE FORMATION DEMONSTRATION OF MICHAELIS-MENTEN KINETICS IN MAN. |
| PubMed: | AUTOMATED ANALYSIS OF SALICYLURIC ACID IN PLASMA AND URINE. |
| PubMed: | [RESEARCH ON SALICYLURIC ACID DURING ACCIDENTAL SALICYLATE POISONING]. |
| PubMed: | Renal disposal of salicyluric acid. |
| PubMed: | [Research on the metabolism of salicylic acid in man. 1. Description of a method for the determination in the urine of the metabolites of salicylic acid and identification of the glucuronides of salicyluric acid]. |
| PubMed: | Occurrence of salicyluric acid in milk. |
| PubMed: | The avidity of salicylic, gentisic, and salicyluric acids for heavy metal cations. |
| PubMed: | Renal metabolism of salicylate and salicylurate. |
| PubMed: | The relative potencies of some substituted salicylic acids as metabolic stimulants in the intact rat. |
| PubMed: | [Metabolic studies on drugs. II. Metabolic products of salicylic, acetylsalicylic, gentisic, and salicyluric acids in rat urine]. |
| PubMed: | [Metabolic studies on drugs. I. Synthesis of radiocarbon labelled salicylic acid (carboxy-C14), acetetylsalicylic acid (carboxy-C14 & acetyl-1-C14), salicyluric acid (carbamyl-C14), and gentisic acid (carboxy-C14)]. |
| PubMed: | Determination of salicylic acid and two metabolites in plasma and urine using fluorimetry for directly measuring salicyluric acid. |