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Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 329.20 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 333.00 °F. TCC ( 167.10 °C. ) (est)
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| logP (o/w): | 1.274 (est) |
| Soluble in: |
| | water, 1.507e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LDLo 500 mg/kg "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 5, Pg. 140, 1953.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for 2,5-dihydroxyacetophenone usage levels up to: | | | not for fragrance use.
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| Recommendation for 2,5-dihydroxyacetophenone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetophenone, 2',5'-dihydroxy- | | 2- | acetyl-1,4-dihydroxybenzene | | 1- | acetyl-2,5-dihydroxybenzene | | 2- | acetylhydroquinone | | 2',5'- | dihydroxy acetophenone | | 1-(2,5- | dihydroxy-phenyl)-ethanone | | 2`,5`- | dihydroxyacetophenone | | 2',5'- | dihydroxyacetophenone | | 2,5- | dihydroxyphenyl methyl ketone | | 1-(2,5- | dihydroxyphenyl)ethan-1-one | | 1-(2,5- | dihydroxyphenyl)ethanone | | | ethanone, 1-(2,5-dihydroxyphenyl)- | | | quinacetophenone |
Articles:
| PubMed: | Tissue protein imaging at 1 μm laser spot diameter for high spatial resolution and high imaging speed using transmission geometry MALDI TOF MS. |
| PubMed: | Pulse-heating ionization for protein on-chip mass spectrometry. |
| PubMed: | A new matrix assisted ionization method for the analysis of volatile and nonvolatile compounds by atmospheric probe mass spectrometry. |
| PubMed: | Aqueous ionic liquid based ultrasonic assisted extraction of four acetophenones from the Chinese medicinal plant Cynanchum bungei Decne. |
| PubMed: | 2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatory responses in lipopolysaccharide-stimulated RAW264.7 macrophages. |
| PubMed: | Chemical constituents of Cynanchum wilfordii and the chemotaxonomy of two species of the family Asclepiadacease, C. wilfordii and C. auriculatum. |
| PubMed: | Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activity. |
| PubMed: | Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation. |
| PubMed: | Laserspray ionization-ion mobility spectrometry-mass spectrometry: baseline separation of isomeric amyloids without the use of solvents desorbed and Ionized directly from a surface. |
| PubMed: | 355 nm multiphoton dissociation and ionization of 2, 5-dihydroxyacetophenone. |
| PubMed: | Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides. |
| PubMed: | [Determination of four acetophenones in Radix Cynanchi bungei by high performance liquid chromatography-photodiode array detection]. |
| PubMed: | Studies on quinones. Part 45: novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines. |
| PubMed: | Photodissociation dynamics of 2,5-dihydroxyacetophenone. |
| PubMed: | 2,5-Dihydroxyacetophenone: a matrix for highly sensitive matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of proteins using manual and automated preparation techniques. |
| PubMed: | Aldose reductase inhibitors from the fruiting bodies of Ganoderma applanatum. |
| PubMed: | Practical enantioselective synthesis of endothelin antagonist S-1255 by dynamic resolution of 4-methoxychromene-3-carboxylic acid intermediate. |
| PubMed: | Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives on tumor cell respiration. |
| PubMed: | Stereochemistry and biological activities of constituents from Cynanchum taiwanianum. |
| PubMed: | Synthesis of 4'- and 5'-hydroxyoxprenolol:pharmacologically active ring-hydroxylated metabolites of oxprenolol. |
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