1-methyl imidazole
1H-imidazole, 1-methyl-
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      616-47-7 Methimazole (Thiamazole) Impurity B > 95%
      1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.
       
       
  • Charkit Chemical
    • Charkit Chemical Corporation
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      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      METHYLIMIDAZOLE, 1-
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
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      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      M0508 1-Methylimidazole >99.0%(GC)
       
  • Zanos
    • Zanos Ltd.
      Distributor of Speciality Chemicals and Natural Ingredients
      Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.
      The flavour and fragrance industry's premier source for aroma chemicals and essential oils
      Zanos Ltd. is a B2B supplier of aroma chemicals, speciality chemicals, natural ingredients and vitamins to a diverse range of customers. In Autumn 2020, Stort Chemicals Limited completed their acquisition of Zanos Ltd. Combining our strengths, Stort and Zanos have boosted our respective portfolios of aroma chemicals, speciality chemicals and natural ingredients. With warehousing facilities across the UK, Rotterdam and Hamburg, Zanos is perfectly positioned to dispatch product throughout Europe.
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      Product(s):
      1-Methylimidazole
       
Synonyms   Articles   Notes   Search
CAS Number: 616-47-7Picture of molecule3D/inchi
Other(deleted CASRN): 110069-11-9
ECHA EINECS - REACH Pre-Reg: 210-484-7
FDA UNII: P4617QS63Y
Nikkaji Web: J1.664K
Beilstein Number: 105197
MDL: MFCD00005292
XlogP3: -0.10 (est)
Molecular Weight: 82.10582000
Formula: C4 H6 N2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.03000 @  25.00 °C.
Refractive Index: 1.49600 @  20.00 °C.
Boiling Point: 195.50 °C. @ 760.00 mm Hg
Vapor Pressure: 0.501000 mmHg @ 25.00 °C. (est)
Flash Point: 198.00 °F. TCC ( 92.22 °C. )
logP (o/w): -0.060
Soluble in:
 water, 1.458e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BASF
1-Methylimidazole
BOC Sciences
For experimental / research use only.
Methimazole (Thiamazole) Impurity B > 95%
Odor: characteristic
Use: 1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.
Charkit Chemical
METHYLIMIDAZOLE, 1-
EMD Millipore
For experimental / research use only.
1-Methylimidazole
Kao Corporation
KAOLIZER NO.110
Odor: characteristic
Use: Catalyst for water blown system, Excellent adhesion and surface curing.
Kun Shan P&A
N-Methylimidazole
Sigma-Aldrich
For experimental / research use only.
1-Methylimidazole puriss., ≥99.0% (GC)
TCI AMERICA
For experimental / research use only.
1-Methylimidazole >99.0%(GC)
Zanos
1-Methylimidazole
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  380 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 14, Pg. 301, 1969.

oral-mouse LD50  1400 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 14, Pg. 301, 1969.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: pharmaceuticals / chemical synthisis
Recommendation for 1-methyl imidazole usage levels up to:
 not for fragrance use.
 
Recommendation for 1-methyl imidazole flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 616-47-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 1390
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 1-methylimidazole
Chemidplus: 0000616477
RTECS: NI7000000 for cas# 616-47-7
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References:
 1-methylimidazole
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 616-47-7
Pubchem (cid): 1390
Pubchem (sid): 134977872
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2933.29.9000
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 imidazole, 1-methyl-
1H-imidazole, 1-methyl-
 methimazole
N-methyl Imidazole
1-methyl-1H-imidazole
1-methylimidazole
1,2-methylimidazole
N-methylimidazole
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Articles:
PubMed: Homogeneous isolation of nanocelluloses by controlling the shearing force and pressure in microenvironment.
PubMed: Optimized GC-MS method to simultaneously quantify acetylated aldose, ketose, and alditol for plant tissues based on derivatization in a methyl sulfoxide/1-methylimidazole system.
PubMed: Ionic liquids supported on magnetic nanoparticles as a sorbent preconcentration material for sulfonylurea herbicides prior to their determination by capillary liquid chromatography.
PubMed: Synthesis of resins with ionic liquids for purification of flavonoids from Hippophae rhamnoides L. leaves.
PubMed: Validation study on avermectine residues in foodstuffs.
PubMed: Research on the adsorption property of supported ionic liquids for ferulic acid, caffeic acid and salicylic acid.
PubMed: Fast and simple droplet sampling of sap from plant tissues and capillary microextraction of soluble saccharides for picogram-scale quantitative determination with GC-MS.
PubMed: Isolation of cellulolytic enzyme lignin from wood preswollen/dissolved in dimethyl sulfoxide/n-methylimidazole.
PubMed: Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents.
PubMed: The derivatisation of avermectins and milbemycins in milk: new insights and improvement of the procedure.
PubMed: Simultaneous determination of emamectin and ivermectin residues in Atlantic salmon muscle by liquid chromatography with fluorescence detection.
PubMed: Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies.
PubMed: Solid-phase extraction cleanup for ivermectin in liver tissue.
PubMed: Ivermectin quantitation with an abamectin internal standard.
PubMed: The determination of choline in vitamin preparations, infant formula and selected foods by capillary zone electrophoresis with indirect ultraviolet detection.
PubMed: Thin-layer chromatographic detection of ivermectin in cattle serum.
PubMed: Liquid chromatographic determination of abamectin in fruits and vegetables.
PubMed: Measurement and characterization of histamine and methylhistamine in human urine under histamine-rich and histamine-poor diets.
PubMed: Highly site-specific oxygenation of 1-methylhistidine and its analogue with a copper (II)/ascorbate-dependent redox system.
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