p-phenylenediamine HCl
1,4-benzenediamine, hydrochloride (1:2)
 
Notes:
None found
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      Product(s):
      P0152 1,4-Phenylenediamine Dihydrochloride ≥99.0%(HPLC)(T)
       
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CAS Number: 624-18-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 210-834-9
FDA UNII: GL418131I1
Beilstein Number: 3911749
MDL: MFCD00013002
Molecular Weight: 181.06370000
Formula: C6 H10 Cl2 N2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: hair dyeing agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: white to slightly reddish crystals or g crystals or powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: hair dyeing agents
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Suppliers:
EMD Millipore
For experimental / research use only.
1,4-Phenylenediammonium dichloride
Santa Cruz Biotechnology
For experimental / research use only.
1,4-Phenylenediamine dihydrochloride 99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,4-Phenylenediamine dihydrochloride ≥99.0%
TCI AMERICA
For experimental / research use only.
1,4-Phenylenediamine Dihydrochloride ≥99.0%(HPLC)(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50  316 mg/kg
Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973

oral-rat LD50  147 mg/kg
Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973

Dermal Toxicity:
subcutaneous-dog LDLo 10 mg/kg
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 42, 1941.

subcutaneous-frog LDLo 10 mg/kg
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 42, 1941.

subcutaneous-mouse LDLo 50 mg/kg
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 42, 1941.

subcutaneous-rabbit LDLo 20 mg/kg
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 42, 1941.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: hair dyeing agents
Recommendation for p-phenylenediamine HCl usage levels up to:
 not for fragrance use.
 
Recommendation for p-phenylenediamine HCl flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 624-18-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 12205
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 3
 benzene-1,4-diamine;dihydrochloride
Chemidplus: 0000624180
EPA/NOAA CAMEO: hazardous materials
RTECS: 624-18-0
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References:
 benzene-1,4-diamine;dihydrochloride
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 624-18-0
Pubchem (cid): 12205
Pubchem (sid): 134977308
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2921.51.1000
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 hair dyeing agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
4-aminoaniline dihydrochloride
p-aminoaniline dihydrochloride
 benzene-1,4-diamine dihydrochloride
 benzene-1,4-diamine dihydrochloride (c.i. 76060)
 benzene-1,4-diamine;dihydrochloride
 benzene-1,4-diammonium chloride
1,4-benzenediamine dihydrochloride
1,4-benzenediamine, hydrochloride (1:2)
 benzol-1,4-diamindihydrochlorid
 c.i. 76060 (HCl)
 C.I. oxidation base 10A
 ci 76060 (HCl)
 CI oxidation base 10A
1,4-diaminobenzene dihydrochloride
p-diaminobenzene dihydrochloride
1,4-diaminobenzenedihydrochloride
 durafur black RC
 fourrine 64
 fourrine D S
 fourrine DS
 pelagol CD
 pelagol grey CD
1,4-phenylene diamine dihydrochloride
p-phenylene diamine dihydrochloride
para-phenylene diamine HCl
1,4-phenylenediamine 2-hydrochloride
1,4-phenylenediamine dihydrochloride
p-phenylenediamine dihydrochloride
para-phenylenediamine dihydrochloride
p-phenylenediamine, dihydrochloride
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