Articles:
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1,3-dioxalane
Notes:
None found
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 04-75450 DIXOLANE
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| CAS Number: | 646-06-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 211-463-5 | |
| FDA UNII: | Y57RBG19JL | |
| Nikkaji Web: | J1.719A | |
| MDL: | MFCD00003207 | |
| XlogP3: | -0.40 (est) | |
| Molecular Weight: | 74.07922000 | |
| Formula: | C3 H6 O2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: solvents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Contact Materials: | 1,3-dioxalane |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.06000 @ 25.00 °C. |
| Melting Point: | -95.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 78.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 79.000000 mmHg @ 20.00 °C. |
| Vapor Density: | 2.6 ( Air = 1 ) |
| Flash Point: | 27.00 °F. TCC ( -2.78 °C. ) |
| logP (o/w): | -0.370 |
| Soluble in: | |
| alcohol | |
| ether | |
| water, 2.769e+005 mg/L @ 25 °C (est) | |
| water, 1.00E+06 mg/L @ 25 °C (exp) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
solvents |
Suppliers:
| Penta International |
| DIXOLANE |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 1,3-Dioxolane |
| Sigma-Aldrich |
| For experimental / research use only. |
| 1,3-Dioxolane ReagentPlus®, contains ∼75 ppm BHT as inhibitor, 99% |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 3000 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 60, 1949. oral-rabbit LD50 5200 mg/kg National Technical Information Service. Vol. OTS0537791 oral-mouse LD50 3200 mg/kg "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. intraperitoneal-rat LDLo 500 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: GENERAL ANESTHETIC KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959. | |
| Dermal Toxicity: | |
|
skin-rat LD50 15000 mg/kg National Technical Information Service. Vol. OTS0537791 skin-rabbit LD50 8480 ul/kg Union Carbide Data Sheet. Vol. 12/17/1971 | |
| Inhalation Toxicity: | |
|
inhalation-rat LC50 20650 mg/m3/4H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. inhalation-mouse LC50 10500 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. inhalation-rabbit LCLo 32000 ppm/4H Union Carbide Data Sheet. Vol. 12/17/1971 | |
Safety in Use Information:
| Category: | solvents | ||
| Recommendation for dioxolane usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dioxolane flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to a 10th list of substances for food contact materials View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 646-06-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 12586 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| 1,3-dioxolane | |
| Chemidplus: | 0000646060 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | JH6760000 for cas# 646-06-0 |
References:
| 1,3-dioxolane | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 646-06-0 |
| Pubchem (cid): | 12586 |
| Pubchem (sid): | 134976960 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2932.90.5000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| allspice japanese allspice Search Trop Picture |
Synonyms:
| 1,3- | dioxalane |
| 1,3- | dioxolan |
| 1,3- | dioxolane |
| 1,3- | dioxole, dihydro- |
| ethylene glycol formal | |
| formal glycol |