1,2-diethyl benzene
benzene, 1,2-diethyl-
 
Notes:
None found
Synonyms   Articles   Notes   Search
CAS Number: 135-01-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 205-170-1
FDA UNII: 25HOX6T1LU
Nikkaji Web: J43.479E
Beilstein Number: 1904392
MDL: MFCD00009258
XlogP3-AA: 3.70 (est)
Molecular Weight: 134.22158000
Formula: C10 H14
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.88000 @  25.00 °C.
Boiling Point: 184.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.050000 mmHg @ 25.00 °C.
Flash Point: 121.00 °F. TCC ( 49.44 °C. )
logP (o/w): 3.720
Soluble in:
 water, 71.1 mg/L @ 20 °C (exp)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
1,2-Diethylbenzene
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,2-Diethylbenzene ≥99.0% (GC)
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LDLo  5000 mg/kg
"Toxicology and Biochemistry of Aromatic Hydrocarbons," Gerarde, H., New York, Elsevier, 1960Vol. -, Pg. 57, 1960.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: natural substances and extractives
Recommendation for 1,2-diethyl benzene usage levels up to:
 not for fragrance use.
 
Recommendation for 1,2-diethyl benzene flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 8657
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 1,2-diethylbenzene
Chemidplus: 0000135013
RTECS: CZ5640000 for cas# 135-01-3
Synonyms   Articles   Notes   Search   Top
References:
 1,2-diethylbenzene
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 8657
Pubchem (sid): 134975245
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2902.90.3050
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 coffee
Search  PMC Picture
 syringa oblata var. alba
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 benzene, 1,2-diethyl-
 benzene, o-diethyl-
ortho-diethyl benzene
1,2-diethylbenzene
o-diethylbenzene
ortho-diethylbenzene
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Olfactory mucosal necrosis in rats following acute intraperitoneal administration of 1,2-diethylbenzene, 1,2-diacetylbenzene and 2,5-hexanedione.
PubMed: The low-melting compounds 1,4-diethyl-, 1,2-diethyl- and ethylbenzene.
PubMed: Organic solvent metabolite, 1,2-diacetylbenzene, impairs neural progenitor cells and hippocampal neurogenesis.
PubMed: Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexane.
PubMed: Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene.
PubMed: Bio-distribution study of 1,2-diethylbenzene and its main metabolites by whole-body autoradiography and tissue homogenates.
PubMed: Using supercritical fluid chromatography to determine diffusion coefficients of 1,2-diethylbenzene, 1,4-diethylbenzene, 5-tert-butyl-m-xylene and phenylacetylene in supercritical carbon dioxide.
PubMed: Environmental metabolite, 1,2-diacetylbenzene, produces cytotoxicity through ROS generation in HUVEC cells.
PubMed: Axonopathy-inducing 1,2-diacetylbenzene forms adducts with motor and cytoskeletal proteins required for axonal transport.
PubMed: A liquid chromatographic-mass spectrometric method to evaluate the distribution kinetics of 1,2-diethylbenzene and its metabolite 1,2-diacetylbenzene in the F344 male rat.
PubMed: A new murine model of giant proximal axonopathy.
PubMed: Aromatic as well as aliphatic hydrocarbon solvent axonopathy.
PubMed: Theoretical determination of chromophores in the chromogenic effects of aromatic neurotoxicants.
PubMed: 1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy.
PubMed: Toxicokinetics and metabolism of 1,2-diethylbenzene in male Sprague Dawley rats--part 2: evidence for in vitro and in vivo stereoselectivity of 1,2-diethylbenzene metabolism.
PubMed: Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene.
PubMed: Assessment of the developmental toxicity and placental transfer of 1,2-diethylbenzene in rats.
PubMed: Biotransformation of diethenylbenzenes, V. Identification of urinary metabolites of 1,2-diethenylbenzene in the rat.
PubMed: Alteration of brainstem auditory evoked potentials in diethylbenzene and diacetylbenzene-treated rats.
PubMed: Possible involvement of 1,2-diacetylbenzene in diethylbenzene-induced neuropathy in rats.
PubMed: Diethylbenzene-induced sensorimotor neuropathy in rats.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2020 Perflavory ™ Disclaimer Privacy Policy