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Category: monomer in epoxy resins for coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 98.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 219.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 505.51 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 525.00 °F. TCC ( 273.60 °C. ) (est)
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| logP (o/w): | 1.240 (est) |
| Soluble in: |
| | water, 21000 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 2500 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(7), Pg. 57, 1974.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | monomer in epoxy resins for coatings |
| Recommendation for trimellitic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for trimellitic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on Food Additives a 4th list of substances for food contact materials View page or View pdf |
Report of ESCO WG on non-plastic Food Contact Materials View page or View pdf |
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 528-44-9 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 10708 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | benzene-1,2,4-tricarboxylic acid |
| Chemidplus: | 0000528449 |
| RTECS: | DC1980000 for cas# 528-44-9 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,2,4- | benzene tricarboxylic acid | | | benzene-1,2,4-tricarboxylic acid | | 1,2,4- | benzenetricarboxylic acid | | 1,2,4- | benzenetricarboxylicacid |
Articles:
| PubMed: | Semiconductor Behavior of a Three-Dimensional Strontium-Based Metal-Organic Framework. |
| PubMed: | Separation of the isomers of benzene poly(carboxylic acid)s by quaternary ammonium salt via formation of deep eutectic solvents. |
| PubMed: | Biotechnological production of muconic acid: current status and future prospects. |
| PubMed: | Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR. |
| PubMed: | Bismuth tri- and tetraarylcarboxylates: crystal structures, in situ X-ray diffraction, intermediates and luminescence. |
| PubMed: | Assembly and properties of transition-metal coordination polymers based on semi-rigid bis-pyridyl-bis-amide ligand: effect of polycarboxylates on the dimensionality. |
| PubMed: | Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice. |
| PubMed: | Simultaneous analysis of acidulants and preservatives in food samples by using capillary zone electrophoresis with indirect UV detection. |
| PubMed: | P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro. |
| PubMed: | CoMn2O4 spinel from a MOF: synthesis, structure and magnetic studies. |
| PubMed: | Effect of self-adhesive resin cement and tribochemical treatment on bond strength to zirconia. |
| PubMed: | Perfluorosulfonic acid membrane catalysts for optical sensing of anhydrides in the gas phase. |
| PubMed: | Design of a new dental adhesive--effect of a water-soluble sodium acylphosphine oxide with crown ether on adhesion to dental hard tissues. |
| PubMed: | Determining organic impurities in mother liquors from oxidative terephthalic acid synthesis by microemulsion electrokinetic chromatography. |
| PubMed: | Sample stacking for determination of aromatic acid impurities by microemulsion electrokinetic chromatography. |
| PubMed: | Complexation and determination of palladium (II) ion with para-Cl-phenylazo-R-acid spectrophotometrically. |
| PubMed: | Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells. |
| PubMed: | Determination of common inorganic anions and cations by non-suppressed ion chromatography with column switching. |
| PubMed: | Effect of solvent type on the degradation of 4-MET. |
| PubMed: | CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity. |
| PubMed: | Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat. |
| PubMed: | Analysis of chemical interaction of 4-MET with hydroxyapatite using XPS. |
| PubMed: | Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels. |
| PubMed: | Asymmetry induction by cooperative intermolecular hydrogen bonds in surface-anchored layers of achiral molecules. |
| PubMed: | Critical design features of phenyl carboxylate-containing polymer microbicides. |
| PubMed: | Simultaneous determination of inorganic anions and organic acids in amine solutions for sour gas treatment by capillary electrophoresis with indirect UV detection. |
| PubMed: | Design of extended surface-supported chiral metal-organic arrays comprising mononuclear iron centers. |
| PubMed: | Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers. |
| PubMed: | A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats. |
| PubMed: | Effects of carboxyl groups on the adsorption behavior of low-molecular-weight substances on a stainless steel surface. |
| PubMed: | Migration of trimellitic acid from epoxy anhydride can coatings into foods. |
| PubMed: | Comparative study on adhesive performance of functional monomers. |
| PubMed: | Synthesis and antimicrobial activity of new adamantane derivatives III. |
| PubMed: | Application of capillary electrophoresis for organic acid analysis in herbal studies. |
| PubMed: | Conformational and quantum analysis of dental adhesive carboxylic acid and carboxylic acid anhydride monomers. |
| PubMed: | Analysis of low molecular weight organic acids in water with capillary zone electrophoresis employing indirect photometric detection. |
| PubMed: | Photoinduced electron-transfer reactions with quinolinic and trimellitic acid imides: experiments and spin density calculations(1) |
| PubMed: | Development of cellulose derivatives as novel enteric coating agents soluble at pH 3.5-4.5 and higher. |
| PubMed: | Acute autoimmune response in a case of pyromellitic acid dianhydride-induced hemorrhagic alveolitis. |
| PubMed: | [Dosimetry using pyromellitic acid and trimellitic acid. Part 1]. |
| PubMed: | Laser-Raman spectroscopic study of the adhesive interface; analysis between 4-META/MMA-TBB resin and bovine or human dentin. |
| PubMed: | Laser-Raman Spectroscopic study of the adhesive interface between 4-MET/MMA-TBB resin and hydroxyapatite or bovine enamel. |
| PubMed: | Construction, characteristics and application of a benzene-1,2,4-tricarboxylic acid selective electrode. |
| PubMed: | Specificity of the human IgE response to inhaled acid anhydrides. |
| PubMed: | Simultaneous determination of trimellitic anhydride and its trimellitic acid impurity by GC/FID. |
| PubMed: | Human antibodies against trimellityl proteins: comparison of specificities of IgG, IgA and IgE classes. |
| PubMed: | Asthma due to inhaled chemical agents--epoxy resin systems containing phthalic acid anhydride, trimellitic acid anhydride and triethylene tetramine. |
| PubMed: | Hydrolysis study of organic acid anhydrides by differential thermal analysis--II. Maleic anhydride and trimellitic anhydride. |
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