1,2,4,5-benzene tetracarboxylic dianhydride
pyromellitic anhydride
 
Notes:
None found
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      Product(s):
      B0040 Pyromellitic Dianhydride >98.0%(T)
       
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CAS Number: 89-32-7Picture of molecule3D/inchi
Other(deleted CASRN): 159104-96-8
ECHA EINECS - REACH Pre-Reg: 201-898-9
FDA UNII: 2Z22T30QZQ
Nikkaji Web: J4.301J
Beilstein Number: 213583
MDL: MFCD00005005
XlogP3-AA: 0.70 (est)
Molecular Weight: 218.12114000
Formula: C10 H2 O6
NMR Predictor: Predict (works with chrome or firefox)
Category: indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FCN 10 Pyromellitic dianhydride View - notice
FCN 151 Pyromellitic dianhydride View - notice
FCN 200 Pyromellitic dianhydride View - notice
FCN 1140 Pyromellitic dianhydride View - notice
FCN 1238 Pyromellitic dianhydride View - notice
FCN 1696 Pyromellitic dianhydride REPLACES FCNs 1140 and 1238 View - notice
DG SANTE Food Contact Materials: pyromellitic anhydride
FDA Mainterm (IAUFC):89-32-7 ; PYROMELLITIC DIANHYDRIDE
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 519.1 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Pyromellitic Dianhydride
Sigma-Aldrich: Aldrich
For experimental / research use only.
Pyromellitic dianhydride 97%
TCI AMERICA
For experimental / research use only.
Pyromellitic Dianhydride >98.0%(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LD50  1595 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(11), Pg. 79, 1986.

oral-mouse LD50  2400 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 125, 1975.

oral-rat LD50  2250 mg/kg
BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(11), Pg. 79, 1986.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LCLo 150 mg/m3/4H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 105, 1982.

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Safety in Use Information:
Category: indirect food additives: adhesives and components of coatings
Recommendation for 1,2,4,5-benzene tetracarboxylic dianhydride usage levels up to:
 not for fragrance use.
 
Recommendation for 1,2,4,5-benzene tetracarboxylic dianhydride flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 89-32-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6966
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 furo[3,4-f][2]benzofuran-1,3,5,7-tetrone
Chemidplus: 0000089327
RTECS: 89-32-7
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References:
 furo[3,4-f][2]benzofuran-1,3,5,7-tetrone
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 89-32-7
Pubchem (cid): 6966
Pubchem (sid): 134972679
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2917.39.7000
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 benzene-1,2:4,5-tetracarboxylic dianhydride
1H,3H-benzo(1,2-c:4,5-c')difuran-1,3,5,7-tetrone
 furo[3,4-f][2]benzofuran-1,3,5,7-tetrone
 pyromellitic 1,2:4,5-dianhydride (6CI)
 pyromellitic acid dianhydride
 pyromellitic anhydride
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