1,1,2-trichlorotrifluoroethane
ethane, 1,1,2-trichloro-1,2,2-trifluoro-
 
Notes:
Used in freezing of foods CFC-113 is a very unreactive chlorofluorocarbon, that will stay in the atmosphere for a great deal of time if it is released. CFC-113 will stay in the atmosphere long enough that it will cycle out of the troposphere and into the stratosphere. In the stratosphere, CFC-113 can be broken up by ultraviolet radiation, creating chlorine radicals, which can in turn react with ozone molecules to form molecular oxygen (O2), leading to the overall depletion of stratospheric ozone. The amount of CFC-113 in the atmosphere has stayed relatively stable, at about 80 parts per trillion, since the early 1990s.; CFC-113 was one of the many forms of CFCs that were made to eliminate toxic and flammable substances in the areas that they were used. It has been used as a cooling agent in refrigerants and air conditioners, aerosol propellant, and a cleansing agent for electrical and electronic components. CFC-113 is one of the three most popular CFCs, along with CFC-11 and CFC-12 and saw much use in its time. CFC-113 has a unique property that makes it perfect for cooling systems. When it is in a gas form and compressed, it heats up, when it is expanded, it cools. This makes them ideal for the vapor compression cycle systems. They were also very desirable because of their low toxicity, non-flammability, thermophysical properties, and normal boiling point. CFC-113 also has a flexible form so it was used in the production of plastics, packaging material, insulation, foams for cushioning, and things like the soles of your shoes. CFC-113 has such a low flammability and low toxicity that it was also used as a cleaner for delicate electrical equipment, fabrics, and even metals. Because it would not warm the product it was cleaning, catch fire with a spark or react to and other chemicals it was ideal for this purpose. CFC-113 in laboratory analytics has been replaced by other solvents.; Trichlorotrifluoroethane, also called 1,1,2-Trichloro-1,2,2-trifluoroethane or CFC-113 is a chlorofluorocarbon. It has the formula Cl2FC-CClF2.
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CAS Number: 76-13-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 200-936-1
FDA UNII: 0739N04X3A
Nikkaji Web: J1.947J
Beilstein Number: 1740335
MDL: MFCD00000782
XlogP3: 3.20 (est)
Molecular Weight: 187.37320960
Formula: C2 Cl3 F3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: extraction solvents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Additive: 1,1,2-Trichlorotrifluoroethane
FDA Mainterm (SATF):76-13-1 ; CHLOROFLUOROCARBON 113
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.342 Chlorofluorocarbon 113 and perfluorohexane.
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Physical Properties:
Appearance: colorless clear liquid (est)
Assay: 99.80 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.57000 @  25.00 °C.
Refractive Index: 1.35800 @  20.00 °C.
Melting Point: -35.00 °C. @ 760.00 mm Hg
Boiling Point: 47.00 to  48.00 °C. @ 760.00 mm Hg
Vapor Pressure: 363.000000 mmHg @ 25.00 °C. (est)
Flash Point: 2.00 °F. TCC ( -16.80 °C. ) (est)
logP (o/w): 3.160
Soluble in:
 water, 170 mg/L @ 25 °C (exp)
 alcohol
 chloroform
 ether
Insoluble in:
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,1,2-Trichlorotrifluoroethane HPLC grade, ≥99.9%
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
R 02 - Risk of explosion by shock, friction, fire or other sources of ignition.
R 52/53 - Harmful to qauatic organisms, may cause long-term adverse effects in the aquatic environment.
R 59 - Dangerous for the ozone layer.
S 02 - Keep out of the reach of children.
S 59 - Refer to manufacturer for information on recovery/recycling.
S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  43000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Medicinal Chemistry. Vol. 7, Pg. 378, 1964.

oral-guinea pig LDLo  > 10000 mg/kg
National Technical Information Service. Vol. OTS0520705

intravenous-mouse LD50  9000 mg/kg
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
National Technical Information Service. Vol. OTS0520355

unreported-mouse LD50  40000 mg/kg
United States Patent Document. Vol. #4164653

oral-rabbit LDLo  17000 mg/kg
American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.

Dermal Toxicity:
skin-rabbit LD50 > 11000 mg/kg
American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.

Inhalation Toxicity:
inhalation-rat LC50 38500 ppm/4H
BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0520341

inhalation-guinea pig LC50 > 12 pph/2H
Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 29, Pg. 381, 1968.

inhalation-mouse LC50 260000 mg/m3/2H
LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 75, Pg. 241, 1963.

inhalation-rabbit LC50 59500 ppm/2H
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: EXCITEMENT SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
National Technical Information Service. Vol. OTS0520343

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Safety in Use Information:
Category: extraction solvents
Recommendation for 1,1,2-trichlorotrifluoroethane usage levels up to:
 not for fragrance use.
 
Recommendation for 1,1,2-trichlorotrifluoroethane flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA-Iris: IRIS
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA Substance Registry Services (TSCA): 76-13-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6428
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 3082
WGK Germany: 2
 1,1,2-trichloro-1,2,2-trifluoroethane
Chemidplus: 0000076131
EPA/NOAA CAMEO: hazardous materials
RTECS: 76-13-1
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References:
 1,1,2-trichloro-1,2,2-trifluoroethane
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 76-13-1
Pubchem (cid): 6428
Pubchem (sid): 134971388
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB31155
FooDB: FDB003169
Export Tariff Code: 2903.40.0020
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
grades: technical; spectrophotometric.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 arcton 113
 asahifron 113
 chlorofluorocarbon 113
 daiflon 113
 delifrene 113
 ethane, 1,1,2-trichloro-1,2,2-trifluoro-
 flugene 113
 forane 113
 freon F113
 frigen 113
 fronsolve 113
 genetron 113
 halocarbon 113
 isceon 113
 khladon 113
 refrigerant 113
1,1,2-trichloro-1,2,2-trifluorethane
 trichloro-1,2,2-trifluoroethane
1,1,2-trichloro-1,2,2-trifluoroethane
1,2,2-trichlorotrifluoroethane
1,1,2-trifluoro-1,2,2-trichloroethane
1,1,2-trifluorotrichloroethane
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