|
Category: extraction solvents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 99.80 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.57000 @ 25.00 °C.
|
| Refractive Index: | 1.35800 @ 20.00 °C.
|
| Melting Point: | -35.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 47.00 to 48.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 363.000000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 2.00 °F. TCC ( -16.80 °C. ) (est)
|
| logP (o/w): | 3.160 |
| Soluble in: |
| | water, 170 mg/L @ 25 °C (exp) | | | alcohol | | | chloroform | | | ether |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | R 02 - Risk of explosion by shock, friction, fire or other sources of ignition. |
R 52/53 - Harmful to qauatic organisms, may cause long-term adverse effects in the aquatic environment. R 59 - Dangerous for the ozone layer. S 02 - Keep out of the reach of children. S 59 - Refer to manufacturer for information on recovery/recycling. S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 43000 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: OTHER CHANGES
SKIN AND APPENDAGES (SKIN): HAIR: OTHER Journal of Medicinal Chemistry. Vol. 7, Pg. 378, 1964.
oral-guinea pig LDLo > 10000 mg/kg National Technical Information Service. Vol. OTS0520705
intravenous-mouse LD50 9000 mg/kg AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) National Technical Information Service. Vol. OTS0520355
unreported-mouse LD50 40000 mg/kg United States Patent Document. Vol. #4164653
oral-rabbit LDLo 17000 mg/kg American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.
|
| Dermal Toxicity: |
skin-rabbit LD50 > 11000 mg/kg American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.
|
| Inhalation Toxicity: |
inhalation-rat LC50 38500 ppm/4H BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: ATAXIA National Technical Information Service. Vol. OTS0520341
inhalation-guinea pig LC50 > 12 pph/2H Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 29, Pg. 381, 1968.
inhalation-mouse LC50 260000 mg/m3/2H LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: ATAXIA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 75, Pg. 241, 1963.
inhalation-rabbit LC50 59500 ppm/2H LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: EXCITEMENT
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE National Technical Information Service. Vol. OTS0520343
|
Safety in Use Information:
| Category: | extraction solvents |
| Recommendation for 1,1,2-trichlorotrifluoroethane usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for 1,1,2-trichlorotrifluoroethane flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | arcton 113 | | | asahifron 113 | | | chlorofluorocarbon 113 | | | daiflon 113 | | | delifrene 113 | | | ethane, 1,1,2-trichloro-1,2,2-trifluoro- | | | flugene 113 | | | forane 113 | | | freon F113 | | | frigen 113 | | | fronsolve 113 | | | genetron 113 | | | halocarbon 113 | | | isceon 113 | | | khladon 113 | | | refrigerant 113 | | 1,1,2- | trichloro-1,2,2-trifluorethane | | | trichloro-1,2,2-trifluoroethane | | 1,1,2- | trichloro-1,2,2-trifluoroethane | | 1,2,2- | trichlorotrifluoroethane | | 1,1,2- | trifluoro-1,2,2-trichloroethane | | 1,1,2- | trifluorotrichloroethane |
Articles:
| PubMed: | Cell adhesion response on femtosecond laser initiated liquid assisted silicon surface. |
| PubMed: | Quantitative assessment of hydrocarbon contamination in soil using reflectance spectroscopy: a "multipath" approach. |
| PubMed: | How to improve reliability in groundwater analysis: over a decade of experience with external quality control in field campaigns on volatile halogenated compounds. |
| PubMed: | Chemical analysis and risk assessment of diethyl phthalate in alcoholic beverages with special regard to unrecorded alcohol. |
| PubMed: | Effects of extracellular purines on cytotoxicity of methotrexate. |
| PubMed: | Breath figure templated self-assembly of porous diblock copolymer films. |
| PubMed: | Determination of furaneol (4-hydroxy-2,5-dimethyl-3(2H)-furanone) in some wines from Italian native grapes by Gas-Chromatography-SIM/MASS spectrometry. |
| PubMed: | Aroma composition of red wines by different extraction methods and Gas Chromatography-SIM/MASS spectrometry analysis. |
| PubMed: | C6, C7, and C8 perfluoroalkyl-substituted phosphinic acids. |
| PubMed: | Isomerization and dissociation of C2X5+ and C2X4+* ions (X = Cl, F) from chlorofluoroethanes in an ion trap mass spectrometer. |
| PubMed: | Positive and negative gas-phase ion chemistry of chlorofluorocarbons in air at atmospheric pressure. |
| PubMed: | Quantitative determination of n-propane, iso-butane, and n-butane by headspace GC-MS in intoxications by inhalation of lighter fluid. |
| PubMed: | Products, rate constants and mechanisms of gas-phase reactions of CX(3)(+), CX(2)(+), CX(+) (X = F and/or Cl) and Cl(+) with 1,1,1- and 1,1,2-trichlorotrifluoroethane. |
| PubMed: | Assay method for the perfluorooctyl bromide (perflubron) in rat blood by gas chromatography-mass spectrometry. |
| PubMed: | Different effects of volatile anesthetics and polyhalogenated alkanes on depolarization-evoked glutamate release in rat cortical brain slices. |
| PubMed: | Highly sensitive detection of swine vesicular disease virus based on a single tube RT-PCR system and DIG-ELISA detection. |
| PubMed: | Biological degradation of VCCs and CFCs under simulated anaerobic landfill conditions in laboratory test digesters. |
| PubMed: | Bimolecular OH rate constants of organic compounds in solution. 2. Measurements in 1,2,2-trichlorotrifluoroethane using hydrogen peroxide as an OH source. |
| PubMed: | Stereoselective determination of R(-)- and S(+)-MK-571, a leukotriene D4 antagonist, in human plasma by chiral high-performance liquid chromatography. |
| PubMed: | Organic photochemistry. 20. A method for estimating gas-phase rate constants for reactions of hydroxyl radicals with organic compounds from their relative rates of reaction with hydrogen peroxide under photolysis in 1,1,2-trichlorotrifluoroethane solution. |
| PubMed: | Effects of Freon-113 on the survival of bacteria. |
| PubMed: | Purification of adenovirus hexon protein by high-performance liquid chromatography. |
| PubMed: | Isolation of a foot-and-mouth disease polyuridylic acid polymerase and its inhibition by antibody. |
| PubMed: | Use of 1,1,2-trichlorotrifluoroethane for the quantitative determination of mineral oil air sample concentrations by u.v. absorption. |
| PubMed: | High-performance liquid-chromatographic analysis for tryptophan in serum. |
|