Articles:
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bis(trimethylsilyl)amine
Notes:
None found
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Charkit Chemical Corporation The Specialty Chemical Specialists Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you. about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals. Email: Sales Voice: 203-299-3220 Fax: 203-299-1355 Facebook Twitter Linkedin Latest News Events Blog Products List: View Product(s): HEXAMETHYLDISILAZANE
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): H0089 1,1,1,3,3,3-Hexamethyldisilazane >96.0%(GC)
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| CAS Number: | 999-97-3 |  3D/inchi
|
| Other(deleted CASRN): | 103737-28-6 | |
| ECHA EINECS - REACH Pre-Reg: | 213-668-5 | |
| FDA UNII: | H36C68P1BH | |
| Nikkaji Web: | J7.217F | |
| Beilstein Number: | 635752 | |
| MDL: | MFCD00008259 | |
| Molecular Weight: | 161.39503000 | |
| Formula: | C6 H19 N Si2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Contact Materials: | hexamethyldisilazane |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.77400 to 0.77800 @ 20.00 °C. |
| Pounds per Gallon - (est).: | 6.448 to 6.481 |
| Refractive Index: | 1.40600 to 1.41000 @ 20.00 °C. |
| Boiling Point: | 125.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 13.800000 mmHg @ 25.00 °C. |
| Flash Point: | 48.00 °F. TCC ( 8.89 °C. ) |
| Soluble in: | |
| water, 392.3 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Charkit Chemical |
| HEXAMETHYLDISILAZANE |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| Hexamethyldisilazane ReagentPlus®, 99.9% |
| TCI AMERICA |
| For experimental / research use only. |
| 1,1,1,3,3,3-Hexamethyldisilazane >96.0%(GC) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-mouse LD50 > 100 mg/kg Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974 oral-mouse LD50 850 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. intraperitoneal-mouse LDLo 650 mg/kg IMMUNOLOGICAL INCLUDING ALLERGIC: DECREASED IMMUNE RESPONSE Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975Vol. 27MAY1975 oral-rabbit LD50 1100 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. intraperitoneal-rat LD50 800 mg/kg SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR National Technical Information Service. Vol. OTS0537734 oral-rat LD50 850 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. | |
| Dermal Toxicity: | |
|
skin-guinea pig LD50 1 mL/kg BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER National Technical Information Service. Vol. OTS0537734 skin-rabbit LD50 710 uL/kg GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 576, 1993. | |
| Inhalation Toxicity: | |
|
inhalation-mouse LC50 12000 mg/m3/2H BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. inhalation-rat LC50 8700 mg/m3/4H CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. | |
Safety in Use Information:
| Category: | indirect food additives: adhesives and components of coatings | ||
| Recommendation for hexamethyldisilazane usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for hexamethyldisilazane flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to the 14th list of substances for food contact materials View page or View pdf | |
| Scientific Opinion on the safety assessment of the substances tetraethyl orthosilicate, CAS No. 78-10-4, and hexamethyldisilazane, CAS No. 999 97 3, for use in food contact materials View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 999-97-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 13838 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| [dimethyl-(trimethylsilylamino)silyl]methane | |
| Chemidplus: | 0000999973 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | JM9230000 for cas# 999-97-3 |
References:
| [dimethyl-(trimethylsilylamino)silyl]methane | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 999-97-3 |
| Pubchem (cid): | 13838 |
| Pubchem (sid): | 134979420 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2931.90.9010 |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| [ | dimethyl-(trimethylsilylamino)silyl]methane |
| disilazane, hexamethyl- | |
| 1,1,1,3,3,3- | hexamethyl disilazane |
| 1,1,1,3,3,3- | hexamethyldisilazane |
| bis(t | rimethylsilyl)amine |