Articles:
benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, (aR)-, hydrochloride (1:1)
Notes:
an alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
-
American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): PHN040 Phenylephrine HCI
-
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 61-76-7 (R)-Phenylephrine Hydrochloride >98% Phenylephrine HCl is a selective à1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure.
-
-
Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GL9617 (R)-(-)-Phenylephrine hydrochloride
-
-
TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): P0398 (R)-(-)-Phenylephrine Hydrochloride >98.0%(HPLC)(T)
-
| CAS Number: | 61-76-7 |  3D/inchi
|
| Other(deleted CASRN): | 50741-76-9 | |
| ECHA EINECS - REACH Pre-Reg: | 200-517-3 | |
| FDA UNII: | 04JA59TNSJ | |
| Beilstein Number: | 4158948 | |
| MDL: | MFCD00012605 | |
| Molecular Weight: | 203.66798000 | |
| Formula: | C9 H14 Cl N O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white microcrystalline powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 142.50 °C. @ 760.00 mm Hg |
| Boiling Point: | 341.10 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000032 mmHg @ 25.00 °C. (est) |
| Flash Point: | 326.00 °F. TCC ( 163.40 °C. ) (est) |
| logP (o/w): | -0.310 |
| Soluble in: | |
| water, 2.931e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| American International Chemical, LLC. |
| Phenylephrine HCI |
| BOC Sciences |
| For experimental / research use only. |
| (R)-Phenylephrine Hydrochloride >98%
Odor: characteristic Use: Phenylephrine HCl is a selective à1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. |
| Glentham Life Sciences |
| (R)-(-)-Phenylephrine hydrochloride |
| Maypro Industries |
| Phenylephrine HCl |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| (R)-(-)-Phenylephrine Hydrochloride |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| (R)-(-)-Phenylephrine hydrochloride powder |
| TCI AMERICA |
| For experimental / research use only. |
| (R)-(-)-Phenylephrine Hydrochloride >98.0%(HPLC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-dog LDLo 16 mg/kg International Journal of Neuropharmacology. Vol. 4, Pg. 219, 1965. intraperitoneal-mouse LD50 89 mg/kg Toxicology and Applied Pharmacology. Vol. 28, Pg. 227, 1974. intravenous-mouse LD50 1120 ug/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD European Journal of Pharmacology. Vol. 9, Pg. 289, 1970. oral-mouse LD50 120 mg/kg International Journal of Neuropharmacology. Vol. 4, Pg. 219, 1965. intramuscular-rabbit LD50 7200 ug/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. intravenous-rabbit LD50 500 ug/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. intraperitoneal-rat LD50 17 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. intravenous-rat LD50 440 ug/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 341, 1955. oral-rat LD50 350 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 22 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. subcutaneous-rabbit LD50 22 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. subcutaneous-rat LD50 27 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 284, 1946. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for (R)-(-)-phenyl ephrine hydrochloride usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for (R)-(-)-phenyl ephrine hydrochloride flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA Substance Registry Services (TSCA): | 61-76-7 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5284443 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride | |
| Chemidplus: | 0000061767 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | DO7525000 for cas# 61-76-7 |
References:
| 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 61-76-7 |
| Pubchem (cid): | 5284443 |
| Pubchem (sid): | 134971205 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| KEGG (GenomeNet): | D00511 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2922.50.1300 |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, (aR)-, hydrochloride | |
| benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, (aR)-, hydrochloride (1:1) | |
| 3-[(1R)-1- | hydroxy-2-(méthylamino)éthyl]phénol chlorhydrate |
| 3-[(1R)-1- | hydroxy-2-(methylamino)ethyl]phenol hydrochloride |
| 3-[(1R)-1- | hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1) |
| 3-[(1R)-1- | hydroxy-2-(methylamino)ethyl]phenol;hydrochloride |
| (aR)-3- | hydroxy-a-((methylamino)methyl)benzenemethanol hydrochloride |
| (R)-3- | hydroxy-a-((methylamino)methyl)benzenemethanol hydrochloride |
| (R)-(-)-3- | hydroxy-a-(methylaminomethyl)benzyl alcohol hydrochloride |
| (R)-3- | hydroxy-a-[(methylamino)methyl]benzenemethanol hydrochloride |
| 1-m- | hydroxy-a-[(methylamino)methyl]benzyl Alcohol Hydrochloride |
| L-a- | hydroxy-b-methylamino-3-hydroxy-1-ethylbenzene hydrochloride |
| (R)-(-)-1-(3- | hydroxyphenyl)-2-methylaminoethanol hydrochloride |
| L-1-(m- | hydroxyphenyl)-2-methylaminoethanol hydrochloride |
| (-)- | phenylephrine hydrochloride |
| (R)- | phenylephrine hydrochloride |
| L- | phenylephrine hydrochloride |
| phenylephrine hydrochloride USP |