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Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 169.00 to 170.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 2.090000 mmHg @ 20.00 °C. (est) |
| Flash Point: | 93.00 °F. TCC ( 33.90 °C. ) (est)
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| logP (o/w): | 0.892 (est) |
| Soluble in: |
| | water, 1930mg/L @ 20 °C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-mouse LD50 180 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04039
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for norcamphor usage levels up to: | | | not for fragrance use.
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| Recommendation for norcamphor flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | bicyclo(2.2.1)-2-heptanone | | | bicyclo(2.2.1)heptan-2-one | | | bicyclo[2.2.1]-2-heptanone | | | bicyclo[2.2.1]heptan-2-one | | | bicyclo[2.2.1]heptan-3-one | | nor | bornan-2-one | | 2-oxonor | bornane | | (±)-2-nor | bornanone | | 2-nor | bornanone | | nor | campher | | (±)-nor | camphor | | 2,5- | methanocyclohexanone | | 8,9,10- | trinorbornan-2-one |
Articles:
| PubMed: | Toxicity Studies on Novel N-Substituted Bicyclo-Heptan-2-Amines at NMDA Receptors. |
| PubMed: | Functional assembly of camphor converting two-component Baeyer-Villiger monooxygenases with a flavin reductase from E. coli. |
| PubMed: | Noncovalently and covalently cross-linked polyurethane gels as alignment media and the suppression of residual polymer signals using diffusion-filtered spectroscopy. |
| PubMed: | Dual action spirobicycloimidazolidine-2,4-diones: antidiabetic agents and inhibitors of aldose reductase-an enzyme involved in diabetic complications. |
| PubMed: | Completing the series of BVMOs involved in camphor metabolism of Pseudomonas putida NCIMB 10007 by identification of the two missing genes, their functional expression in E. coli, and biochemical characterization. |
| PubMed: | An automated microscale platform for evaluation and optimization of oxidative bioconversion processes. |
| PubMed: | Time-dependent fifth-order bands in nominally third-order 2D IR vibrational echo spectra. |
| PubMed: | Syntheses and pharmacological evaluations of novel N-substituted bicyclo-heptane-2-amines at N-methyl-D-aspartate receptors. |
| PubMed: | The effect of proton donors on the facial stereoselectivity in SmI2 reduction of norcamphor. |
| PubMed: | Spring-loading the active site of cytochrome P450cam. |
| PubMed: | A technique for recording polycrystalline structure and orientation during in situ deformation cycles of rock analogues using an automated fabric analyser. |
| PubMed: | Benzoyl radicals from (hetero)aromatic aldehydes. Decatungstate photocatalyzed synthesis of substituted aromatic ketones. |
| PubMed: | Absolute configuration assignment of norcamphor-derived furyl hydroperoxide using density functional theory calculations of optical rotation and vibrational circular dichroism. |
| PubMed: | Comparative analysis of IR and vibrational circular dichroism spectra for a series of camphor-related molecules. |
| PubMed: | Calculation of electronic circular dichroism spectra with time-dependent double-hybrid density functional theory. |
| PubMed: | Regiodivergent Baeyer-Villiger oxidation of fused ketones by recombinant whole-cell biocatalysts. |
| PubMed: | The effect of carbonyl group in the asymmetry of 3,4JCH coupling constants in norbornanones. |
| PubMed: | Expectation and surprise in group 13 organometallics: molecular vs. polymeric aggregation of Me2Ga and Me2In norcamphor oximates. |
| PubMed: | Organoaluminium complexes with sterically demanding oximato ligands: does a bulky and rigid ligand backbone change the aggregation motif? |
| PubMed: | Cytochrome P450cam-monoterpene interactions. |
| PubMed: | Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy. |
| PubMed: | Ketone synthesis by intramolecular acylation of organorhodium(I) with ester. |
| PubMed: | Polarizable continuum model study of solvent effects on electronic circular dichroism parameters. |
| PubMed: | Identification and structure-activity relationship studies of 3-methylene-2-norbornanone as potent anti-proliferative agents presumably working through p53 mediated apoptosis. |
| PubMed: | The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site. |
| PubMed: | Base-promoted reactions of bridged ketones and 1,3- and 1,4-haloalkyl azides: competitive alkylation vs azidation reactions of ketone enolates. |
| PubMed: | Substrate modulates compound I formation in peroxide shunt pathway of Pseudomonas putida cytochrome P450(cam). |
| PubMed: | Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam. |
| PubMed: | Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101). A high-pressure stopped-flow study. |
| PubMed: | Stereoelectronic, torsional, and steric effects on rates of enolization of ketones. |
| PubMed: | Conformational relaxation in hemoproteins: the cytochrome P-450cam case. |
| PubMed: | Step-scan time-resolved FTIR spectroscopy of cytochrome P-450cam carbon monoxide complex: a salt link involved in the ligand-rebinding process. |
| PubMed: | Mobility of norbornane-type substrates and water accessibility in cytochrome P-450cam. |
| PubMed: | Stereoselective hydroxylation of norcamphor by cytochrome P450cam. Experimental verification of molecular dynamics simulations. |
| PubMed: | EPR studies on the photoproducts of ferric cytochrome P450cam (CYP101) nitrosyl complexes: effects of camphor and its analogues on ligand-bound structures. |
| PubMed: | High-pressure flash photolysis study of hemoprotein: effects of substrate analogues on the recombination of carbon monoxide to cytochrome P450CAM. |
| PubMed: | Substrate mobility in thiocamphor-bound cytochrome P450cam: an explanation of the conflict between the observed product profile and the X-ray structure. |
| PubMed: | Controlling the regiospecificity and coupling of cytochrome P450cam: T185F mutant increases coupling and abolishes 3-hydroxynorcamphor product. |
| PubMed: | Heme-pocket-hydration change during the inactivation of cytochrome P-450camphor by hydrostatic pressure. |
| PubMed: | Predicting the product specificity and coupling of cytochrome P450cam. |
| PubMed: | Substrate mobility in a deeply buried active site: analysis of norcamphor bound to cytochrome P-450cam as determined by a 201-psec molecular dynamics simulation. |
| PubMed: | The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM. |
| PubMed: | Deuterium isotope effects in norcamphor metabolism by cytochrome P-450cam: kinetic evidence for the two-electron reduction of a high-valent iron-oxo intermediate. |
| PubMed: | Theoretical study of the product specificity in the hydroxylation of camphor, norcamphor, 5,5-difluorocamphor, and pericyclocamphanone by cytochrome P-450cam. |
| PubMed: | Regiochemistry of Camphor Analog Oxidation by Pseudomonas putida. |
| PubMed: | Nitrogen mustards derived from alpha-hydroxymethyleneketones. |
| PubMed: | Autooxidation and hydroxylation reactions of oxygenated cytochrome P-450cam. |
| PubMed: | Metabolism of camphors and related compounds. |
| PubMed: | exo-3-chloro-endo-6-cyano-2-norbornanone o-(methylcarbamoyl)oxime. A new type of methylcarbamate with acaricidal activity. |
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