Articles:
| Info: | Indigotin |
indigotine
Notes:
indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk. Colour additive for food
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 860-22-0 Indigo Carmine PRACTICAL
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GT4851 Indigo Carmine (C.I. 73015)
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): I0214 Indigo Carmine >95.0%(E)
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| CAS Number: | 860-22-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 212-728-8 | |
| FDA UNII: | D3741U8K7L | |
| Beilstein Number: | 4103904 | |
| MDL: | MFCD00005723 | |
| Molecular Weight: | 468.37283856 | |
| Formula: | C16 H10 N2 Na2 O8 S2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: coloring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| EU SANCO | Indigotine, Indigo carmine View - review |
| JECFA Food Additive: | Indigotine |
| GSFA Codex: | Indigotine (Indigo carmine) (132) |
| DG SANTE Food Additives: | indigotine |
| FDA Mainterm (SATF): | 860-22-0 ; FD&C BLUE NO. 2 |
| FDA Regulation: | |
| FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart A--Foods Sec. 74.102 FD&C Blue No. 2. FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart B--Drugs Sec. 74.1102 FD&C Blue No. 2. FDA PART 82 -- LISTING OF CERTIFIED PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Subpart B--Foods, Drugs, and Cosmetics Sec. 82.102 FD&C Blue No. 2. | |
Physical Properties:
| Appearance: | blue powder (est) |
| Assay: | 85.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | 1.627 (est) |
| Soluble in: | |
| water, 1e+006 mg/L @ 25 °C (est) | |
| water, 1.00E+04 mg/L @ 25 °C (exp) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data2 |
| CosIng: | cosmetic data |
| Cosmetic Uses: |
cosmetic colorants |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Indigo Carmine PRACTICAL |
| EMD Millipore |
| For experimental / research use only. |
| Indigo carmine (C.I. 73015) |
| Flavorchem |
| FD&C Blue No. 2 |
| Glentham Life Sciences |
| Indigo Carmine (C.I. 73015) |
| Kishi Kasei |
| Blue No.2 |
| Pangaea Sciences |
| Indigo |
| Rung International |
| FD&C Blue No.2 |
| Rung International |
| Lake Indigo Carmine |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Indigo carmine |
| Sigma-Aldrich |
| For experimental / research use only. |
| Indigo carmine
analytical standard |
| TCI AMERICA |
| For experimental / research use only. |
| Indigo Carmine >95.0%(E) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 2000 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. oral-mouse LD50 2500 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. intravenous-rat LD50 93 mg/kg Drugs in Japan Vol. 6, Pg. 83, 1982. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 405 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | coloring agents | ||
| Recommendation for fd&c blue no. 2 (c.i. 73015 (Na)) usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for fd&c blue no. 2 (c.i. 73015 (Na)) flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific Opinion on the re-evaluation of Indigo Carmine (E 132) as a food additive View page or View pdf | |
| Scientific Opinion on the safety and efficacy of indigo carmine (E 132) for cats and dogs and ornamental fish View page or View pdf | |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 860-22-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5282429 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| disodium;(2E)-3-oxo-2-(3-oxo-5-sulfo-1H-indol-2-ylidene)-1H-indole-5-sulfonic acid | |
| Chemidplus: | 0000860220 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | DU3000000 for cas# 860-22-0 |
References:
| disodium;(2E)-3-oxo-2-(3-oxo-5-sulfo-1H-indol-2-ylidene)-1H-indole-5-sulfonic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 860-22-0 |
| Pubchem (cid): | 5282429 |
| Pubchem (sid): | 134980234 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB011141 |
| Export Tariff Code: | 3204.12.0000 |
| FDA Color Additive Status List | View |
| ChemSpider: | View |
| Formulations/Preparations: marketed as a paste with water; the dye contents varying according to specification or requirements of the user. it almost always contains sodium chloride or sulfate used for "salting" it out. | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| cosmetic colorants | ||
| hair dyeing agents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| acid blue 74 | |
| acid blue 74 (c.i. 73015 (Na)) | |
| (d(sup 2,2')- | biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt |
| (d2,2'- | biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt |
| c.i. 73015 (Na) | |
| c.i. 75781 | |
| C.I. food blue 1, disodium salt | |
| C.I. natural blue 2 | |
| ci 73015 (Na) | |
| ci 75781 | |
| 2-(1,3- | dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic acid, disodium salt |
| disodium 3,3'-dioxo-(d(sup 2,2')-biindoline)-5,5'-disulfonate | |
| disodium 3,3'-dioxo-(d2,2'-biindoline)-5,5'-disulfonate | |
| disodium 5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-ylidene)-1,2-dihydro-3H-indol-3-one) disulfonate (c.i. 73015) | |
| disodium 5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-ylidene)-1,2-dihydro-3H-indol-3-one)disulphonate | |
| disodium 5,5'-indigotin disulfonate | |
| disodium indigo-5,5-disulfonate | |
| disodium salt of 1-indigotin-s,s'-disulfonic acid | |
| disodium salt of 1-indigotin-S,S'-disulphonic acid | |
| fd&c blue no. 2 (c.i. 73015 (Na)) | |
| food blue 1 | |
| food blue 1 disodium salt | |
| food blue no. 1 | |
| indigo carmine (c.i. 73015 (Na)) | |
| 5,5- | indigo disulfonic acid disodium salt (c.i. 73015 (Na)) |
| indigotin-5,5'-disulfonic acid disodium salt | |
| indigotine | |
| 1H- | indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt |
| natural blue 2 | |
| sodium 5,5'-indigotindisulfonate | |
| sodium indigo-5,5'-bisulfonate | |
| usacert blue no. 2 |