Articles:
| None found yet. Try the PubMed Search. |
erythrosine
Notes:
a tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of dental plaque, and as a stain of some cell types. it has structural similarity to thyroxine. Dye used in food and feed additives. Prohibited in U.S.A. and Norway [DFC]
Erythrosine, also known as Red No. 3, is a cherry-pink synthetic fluorone food coloring. It is the disodium salt of 2,4,5,7-tetraiodofluorescein. Erythrosine is commonly used in sweets such as some candies and popsicles, and even more widely used in cake-decorating gels. While commonly used in many countries of the world, erythrosine is less commonly used in the United States because Allura Red AC (Red #40) is generally used instead. However, Allura Red AC is banned in many European countries solely because it is an azo dye, despite scientific consensus of Red 40 having fewer known health risks. [Wikipedia]
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 16423-68-0 Erythrosine > 95% Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.
-
-
Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GT2668 Erythrosin B sodium salt (C.I. 45430) GT8461 Erythrosin B sodium salt (C.I. 45430), certified
-
-
TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): T0557 Erythrosine B >95.0%(E)
-
| CAS Number: | 16423-68-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 240-474-8 | |
| FDA UNII: | 8TL7LH93FM | |
| Nikkaji Web: | J77.650E | |
| Beilstein Number: | 1443945 | |
| MDL: | MFCD00144257 | |
| Molecular Weight: | 881.87717856 | |
| Formula: | C20 H8 I4 Na2 O5 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: coloring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| EU SANCO | Erythrosine View - review |
| JECFA Food Additive: | Erythrosine |
| GSFA Codex: | Erythrosine (127) |
| DG SANTE Food Additives: | erythrosine |
| FDA Mainterm (SATF): | 16423-68-0 ; FD&C RED NO. 3 |
| FDA Regulation: | |
| FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart B--Drugs Sec. 74.1303 FD&C Red No. 3. FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart A--Foods Sec. 74.303 FD&C Red No. 3. FDA PART 81 -- GENERAL SPECIFICATIONS AND GENERAL RESTRICTIONS FOR PROVISIONAL COLOR ADDITIVES FOR USE IN FOODS, DRUGS, AND COSMETICS Sec. 81.10 Termination of provisional listings of color additives | |
Physical Properties:
| Appearance: | red powder (est) |
| Assay: | 87.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | -0.290 |
| Soluble in: | |
| alcohol | |
| water | |
| water, 2.29 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
cosmetic colorants |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Erythrosine > 95%
Odor: characteristic Use: Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products. |
| EMD Millipore |
| For experimental / research use only. |
| Erythrosine B (C.I. 45430) |
| Flavorchem |
| FD&C Red No. 3 |
| Glentham Life Sciences |
| Erythrosin B sodium salt (C.I. 45430), certified |
| Glentham Life Sciences |
| Erythrosin B sodium salt (C.I. 45430) |
| Kishi Kasei |
| Red No.3 |
| Prinova |
| Color-Red #3 |
| Rung International |
| Erythrosine |
| Rung International |
| FD&C Red No.3 |
| Rung International |
| Lake Erythrosine |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Erythrosin extra bluish |
| Sigma-Aldrich |
| For experimental / research use only. |
| Erythrosin B
analytical standard |
| TCI AMERICA |
| For experimental / research use only. |
| Erythrosine B >95.0%(E) |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
|
R 22 - Harmful if swallowed. S 02 - Keep out of the reach of children. S 22 - Do not breath dust. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 1840 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. oral-mouse LD50 1264 mg/kg Eastern Pharmacist. Vol. 24, Pg. 125, 1981. intravenous-mouse LD50 370 mg/kg Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 9, Pg. 127, 1952. intravenous-rabbit LD50 200 mg/kg FAO Nutrition Meetings Report Series. Vol. 38B, Pg. 50, 1966. intraperitoneal-rat LD50 300 mg/kg FAO Nutrition Meetings Report Series. Vol. 38B, Pg. 50, 1966. intravenous-rat LD50 200 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. unreported-rat LD50 1895 mg/kg Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 30, Pg. 179, 1979. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | coloring agents | ||
| Recommendation for fd&c red no. 3 (c.i. 45430 (Na)) usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for fd&c red no. 3 (c.i. 45430 (Na)) flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific Opinion on the re-evaluation of Erythrosine (E 127) as a food additive View page or View pdf | |
| Scientific Opinion on the safety and efficacy of erythrosine in feed for cats and dogs, ornamental fish and reptiles View page or View pdf | |
| Update of the Scientific Opinion on the safety and efficacy of erythrosine in feed for cats, dogs, reptiles and ornamental fish View page or View pdf | |
| Safety of erythrosine for ornamental fish View page or View pdf | |
| EPI System: | View |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 16423-68-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 27872 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| disodium;2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl)benzoate | |
| Chemidplus: | 0016423680 |
| RTECS: | LM5950000 for cas# 16423-68-0 |
References:
| disodium;2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl)benzoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 16423-68-0 |
| Pubchem (cid): | 27872 |
| Pubchem (sid): | 135017864 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | HMDB29702 |
| FooDB: | FDB000892 |
| Export Tariff Code: | 2932.99.7000 |
| FDA Color Additive Status List | View |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| cosmetic colorants | ||
| hair dyeing agents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| acid red 51 (c.i. 45430 (Na)) | |
| benzoic acid, 2-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, sodium salt (1:2) | |
| c.i. 45430 (Na) | |
| ci 45430 (Na) | |
| 3',6- | dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'(9H)xanthen)-one disodium salt |
| 3',6'- | dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'[9H]xanthen]-3-one disodium salt |
| disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate | |
| disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl) benzoate (c.i. 45430 (Na)) | |
| disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate | |
| disodium 2',4',5',7'-tetraiodofluorescein | |
| erythrosin B (c.i. 45430 (Na)) | |
| erythrosin B sodium salt | |
| erythrosine | |
| fd&c red 3 | |
| fd&c red no. 3 (c.i. 45430 (Na)) | |
| fluorescein, 2',4',5',7'-tetraiodo-, disodium salt | |
| food dye red 3 | |
| food red 14 | |
| food red no. 3 | |
| 2-(6- | hydroxy-2,4,5,7-tetraiodo-3-oxoxanthen-9-yl)benzoic acid, sodium salt, sodium salt |
| red dye no. 3 | |
| 2',4',5',7'- | tetraiodofluorescein, disodium salt |
| 2',4',5',7'- | tetraiodofluoroescein disodium salt |