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ponceau 4R
Notes:
Synthetic food colouring
Because it is an azo dye, it may elicit intolerance in people allergic to salicylates (aspirin). Additionally, it is a histamine liberator, and may intensify symptoms of asthma.; Ponceau 4R (also known as Food Red 7[citation needed], C.I. 16255[citation needed], Cochineal Red A[citation needed], New Coccine, Acid Red 18, SX purple[citation needed]) is a synthetic colourant that may be added to foods to induce a colour change. It is denoted by E Number E124, and has the capacity for inducing an allergic reaction. Its chemical name is trisodium salt of 1-(4-sulpho-1-napthylazo)- 2-napthol- 6,8-disulphonic acid.; Ponceau 4R is a red azo dye usually synthesized from coal tar which can be used in a variety of food products.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GT7227 Ponceau 4R (C.I. 16255)
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Moellhausen S.P.A. THE CHEMISTRY OF EMOTIONS Innovation and commitment in the name of excellence. After 50 years in business, Moellhausen stands out as one of the world’s leading family-run companies in the industry of flavors and fragrances, raw materials, and specialties. Voice: +39 039.685.6262 Fax: +39 039.685.6263 Facebook Twitter Linkedin Youtube A network of knowledge to grow together Sustainability is at the foundation of a Pervasive technology and total control Product(s): 1000242 COLOUR RED PONCEAU E124
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): N0309 Acid Red 18 >85.0%(E)
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| CAS Number: | 2611-82-7 |  3D/inchi
|
| Other(deleted CASRN): | 11138-24-2 | |
| ECHA EINECS - REACH Pre-Reg: | 220-036-2 | |
| FDA UNII: | Z525CBK9PG | |
| Beilstein Number: | 4122340 | |
| MDL: | MFCD00004084 | |
| Molecular Weight: | 604.47797784 | |
| Formula: | C20 H11 N2 Na3 O10 S3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: coloring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| EU SANCO | Ponceau 4R, Cochineal Red A View - review |
| JECFA Food Additive: | Ponceau 4R |
| GSFA Codex: | Ponceau 4R (Cochineal red A) (124) |
| DG SANTE Food Additives: | ponceau 4R |
Physical Properties:
| Appearance: | reddish powder (est) |
| Assay: | 85.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | 1.346 (est) |
| Soluble in: | |
| water, 8.00E+04 mg/L @ 25 °C (exp) | |
| alcohol, slightly | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data2 |
| CosIng: | cosmetic data |
| Cosmetic Uses: |
cosmetic colorants hair dyeing agents |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| New Coccine Dye conte |
| Glentham Life Sciences |
| Ponceau 4R (C.I. 16255) |
| Kishi Kasei |
| Red No.102 |
| Moellhausen |
| COLOUR RED PONCEAU E124 |
| Rung International |
| Lake Ponceau 4R |
| Rung International |
| Ponceau 4R |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| New coccine |
| Sigma-Aldrich |
| For experimental / research use only. |
| Ponceau 4R |
| TCI AMERICA |
| For experimental / research use only. |
| Acid Red 18 >85.0%(E) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 > 8000 mg/kg KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967. intraperitoneal-mouse LD50 1600 mg/kg BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967. oral-mouse LDLo 8000 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. intraperitoneal-rat LD50 600 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: COMA Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967. intravenous-rat LD50 1000 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. unreported-rat LD50 2000 mg/kg Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 30, Pg. 179, 1979. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | coloring agents | ||
| Recommendation for ci 16255 usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for ci 16255 flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific Opinion on the re-evaluation of Ponceau 4R (E 124) as a food additive View page or View pdf | |
| Assessment of the results of the study by McCann et al. (2007) on the effect of some colours and sodium benzoate on children’s behaviour [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC) View page or View pdf | |
| Statement on Allura Red AC and other sulphonated mono azo dyes authorised as food and feed additives View page or View pdf | |
| Refined exposure assessment for Ponceau 4R (E 124) View page or View pdf | |
| Safety and efficacy of ponceau 4R for cats, dogs and ornamental fish View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 2611-82-7 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 9570119 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate | |
| Chemidplus: | 0002611827 |
| RTECS: | QJ6530000 for cas# 2611-82-7 |
References:
| trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 2611-82-7 |
| Pubchem (cid): | 9570119 |
| Pubchem (sid): | 134981627 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| KEGG (GenomeNet): | C20344 |
| HMDB (The Human Metabolome Database): | HMDB29855 |
| FooDB: | FDB001076 |
| Export Tariff Code: | 3204.12.5090 |
| FDA Color Additive Status List | View |
| ChemSpider: | View |
| Wikipedia: | View |
| FAO: | PONCEAU 4R |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| cosmetic colorants | ||
| hair dyeing agents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| acid brilliant scarlet 3R | |
| acid ponceau 4R | |
| acid red 18 (c.i. 16255) | |
| acid scarlet 3R | |
| brilliant ponceau 3R | |
| brilliant scarlet 3R | |
| c.i. 16255 | |
| C.I. acid red 18, trisodium salt | |
| calcocid brilliant scarlet 3RN | |
| cochineal red A | |
| food red 7 | |
| 7- | hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalene disulfonic acid trisodium salt |
| 7- | hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfon- ic acid, trisodium salt |
| 7- | hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfonic acid trisodium salt |
| naphthalene scarlet 4R | |
| 1,3- | naphthalenedisulfonic acid, 7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-, trisodium salt |
| new coccine (c.i. 16255) | |
| ponceau 4R | |
| scarlet 4R | |
| 1-(4- | sulpho-1-naphthylazo)-2-naphthol-6,8-disulphonic acid, trisodium salt |
| trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate | |
| trisodium 1-(1-naphthyl azo)-2-hydroxynaphthalene-4',6,8-trisulfonate (c.i. 16255) | |
| victoria scarlet 3R |