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Category: antioxidants and preservatives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 96.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| logP (o/w): | 12.260 (est) |
| Soluble in: |
| | water, 3.653e-008 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 5000 mg/kg Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
intraperitoneal-mouse LD50 5000 mg/kg Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | antioxidants and preservatives |
| Recommendation for dextro,laevo-alpha-vitamin E acetate usage levels up to: | | | not for fragrance use.
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| Recommendation for dextro,laevo-alpha-vitamin E acetate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Inability to assess the safety of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol added for nutritional purposes as sources of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl- tocotrienol in food supplements and the bioavailability of beta-, gamma-, delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol from the different sources, based on the supporting dossiers [1] View page or View pdf |
Safety assessment of the substance a-tocopherol acetate for use in food contact materials View page or View pdf |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA Substance Registry Services (TSCA): | 7695-91-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 86472 |
| National Institute of Allergy and Infectious Diseases: | Data |
| SCCNFP: | opinion |
| WGK Germany: | 1 |
| | [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate |
| Chemidplus: | 0007695912 |
| RTECS: | GA8747000 for cas# 7695-91-2 |
| Chemidplus: | 0000058957 |
| EPA/NOAA CAMEO: | hazardous materials |
References:
| | [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 7695-91-2 |
| Pubchem (cid): | 86472 |
| Pubchem (sid): | 135042796 |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 1406-70-8 |
| Pubchem (cid): | 2117 |
| Pubchem (sid): | 148889 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3,4- | dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl tridecyl)-2H-benzopyran-6-yl acetate | | [(2R)-2,5,7,8- | tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate | | (+-)-alpha- | tocopherol acetate | | DL-alpha- | tocopheryl acetate | | dextro,laevo-alpha- | tocopheryl acetate | | DL-alpha- | vitamin E acetate |
Articles:
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