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Category: nutrient supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 63.00 to 65.00 °C. @ 760.00 mm Hg
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| logP (o/w): | 5.680 |
| Soluble in: |
| | water, 0.6713 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 2000 mg/kg Acta Dermato-Venereologica, Supplementum. Vol. 74, Pg. 29, 1975.
oral-mouse LD50 1510 mg/kg "The Retinoids, Vol.2," Sporn, M.B., et al., eds., New York, Academic Press, Inc., 1984Vol. 2, Pg. 287, 1984.
intraperitoneal-mouse LD50 1510 mg/kg Journal of the American Academy of Dermatology. Vol. 6, Pg. 652, 1982.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | nutrient supplements |
| Recommendation for vitamin A usage levels up to: | | | not for fragrance use.
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| Recommendation for vitamin A flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Scientific Opinion on the substantiation of a health claim related to vitamin A and contribution to normal development and function of the immune system pursuant to Article 14 of Regulation (EC) No 1924/2006 View page or View pdf |
Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for vitamin A View page or View pdf |
Scientific Opinion on Dietary Reference Values for vitamin A View page or View pdf |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 68-26-8 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 445354 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol |
| Chemidplus: | 0000068268 |
| | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol |
| Chemidplus: | 0011103574 |
| EPA/NOAA CAMEO: | hazardous materials |
References:
| | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 68-26-8 |
| Pubchem (cid): | 445354 |
| Pubchem (sid): | 149148 |
| | (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 11103-57-4 |
| Pubchem (cid): | 445354 |
| Pubchem (sid): | 168221 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C00473 |
| HMDB (The Human Metabolome Database): | HMDB00305 |
| FooDB: | FDB013828 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| Wikipedia: | View |
Formulations/Preparations: •aqueous soln (dispersions) of oil-soluble vit are prepared by the use of an emulsifying agent such as polysorbate 80.
•there are many types of preparations that contain retinol. these include solutions of pure synthetic retinol and concentrates that contain both retinol and vitamin d in various proportions. vitamin a capsules contain 3 to 15 mg of retinol (10,000 to 50,000 usp vitamin a units) per capsule: tablets are also available. a water-miscible preparation (15 mgml; 50,000 usp unitsml) can be given intramuscularly. tretinoin (all-trans-retinoic acid; retin-a) is available for topical use as a solution (0.05%), a cream (0.05 and 0.1%), and a gel (0.025 and 0.01%). isotretinoin (13-cis-retinoic acid; accutane) is available for oral use as 10, 20, and 40 mg capsules.
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (all-E)-3,7- | dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol | | all-trans-3,7- | dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol | | 3,7- | dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)- | | (2E,4E,6E,8E)-3,7- | dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-1-nona-2,4,6,8-tetraenol | | (2E,4E,6E,8E)-3,7- | dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol | | (2E,4E,6E,8E)-3,7- | dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetr aen-1-ol | | (2E,4E,6E,8E)-3,7- | dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol | | 2,4,6,8- | nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)- | | 2,6,8- | nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)- | | | retinol | | all-trans- | retinol | | all-trans- | retinyl alcohol | | | vitamin A | | all-trans- | vitamin A | | all-trans- | vitamin A alcohol |
Articles:
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