laureth-8
poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (8 mol EO average molar ratio)
 
Notes:
polyethylene glycol monododecyl ether (average polymer n=9).
  • BOC Sciences
    • BOC Sciences
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      Product(s):
      3055-98-9 Octaethylene glycol monododecyl ether 95%
       
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CAS Number: 9002-92-0Picture of molecule3D/inchi
Other(deleted CASRN): 101008-55-3
ECHA ELINCS - REACH Pre-Reg: 500-002-6
FDA UNII: J89TKQ5R54
Nikkaji Web: J92.963H
XlogP3: 5.10 (est)
Formula: (C2 H4 O)mult-C12 H26 O
NMR Predictor: Predict (works with chrome or firefox)
CAS Number: 3055-98-9Picture of molecule3D/inchi
Nikkaji Web: J208.815K
XlogP3: 4.10 (est)
Molecular Weight: 538.76306000
Formula: C28 H58 O9
NMR Predictor: Predict (works with chrome or firefox)
Category: emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: colorless to pale yellow clear viscous liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 304.36 °C. @ 760.00 mm Hg (est)
Flash Point: 167.00 °F. TCC ( 74.90 °C. ) (est)
logP (o/w): 4.909 (est)
Soluble in:
 water, 11.31 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: surfactants
surfactant - emulsifying
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Suppliers:
BOC Sciences
For experimental / research use only.
Octaethylene glycol monododecyl ether 95%
Chemical-navi - Nikkol
NIKKOL BL-8SY
Odor: characteristic
Use: Reagent of nonionic surfactant
Kao Corporation
AKYPO ROX RLM80V
Odor: characteristic
Use: Detergent, foaming, wetting, dispersing agent, emulsifier and solubilizer for different fields
Stepan Company
BIO-SOFT® EC-639
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-guinea pig LD50  38 mg/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.

oral-guinea pig LD50  384 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.

intraperitoneal-mouse LD50  160 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.

intraperitoneal-mouse LD50  160 mg/kg
Drugs in Japan Vol. -, Pg. 1300, 1995.

intravenous-mouse LD50  100 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.

intravenous-mouse LD50  100 mg/kg
Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965.

oral-mouse LD50  1170 mg/kg
Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.

oral-mouse LD50  1170 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.

oral-mouse LD50  3500 mg/kg
American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.

oral-mouse LD50  4940 mg/kg
American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.

intratracheal-rabbit LD50  > 15 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.

intravenous-rabbit LD50  36 mg/kg
KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.

parenteral-rabbit LD50  > 75 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.

intraperitoneal-rat LD50  125 mg/kg
GASTROINTESTINAL: OTHER CHANGES
Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.

intravenous-rat LD50  27 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.

intravenous-rat LD50  27 mg/kg
Drugs in Japan Vol. -, Pg. 1300, 1995.

intravenous-rat LD50  390 mg/kg
Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.

oral-rat LD50  1000 mg/kg
LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.

oral-rat LD50  4150 mg/kg
Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.

oral-rat LD50  8600 mg/kg
Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.

Dermal Toxicity:
subcutaneous-mouse LD50 792 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.

subcutaneous-mouse LD50 792300 ug/kg
Drugs in Japan Vol. -, Pg. 1300, 1995.

subcutaneous-rat LD50 953 mg/kg
Drugs in Japan Vol. -, Pg. 1300, 1995.

subcutaneous-rat LD50 954 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emulsifiers, surfactants
Recommendation for laureth-8 usage levels up to:
 not for fragrance use.
 
Recommendation for laureth-8 flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 9002-92-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24750
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 2-dodecoxyethanol (peg-8)
Chemidplus: 0009002920
EPA/NOAA CAMEO: hazardous materials
 2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Chemidplus: 0003055989
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References:
 2-dodecoxyethanol (peg-8)
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 9002-92-0
Pubchem (cid): 24750
Pubchem (sid): 134991393
 2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 3055-98-9
Pubchem (cid): 123921
Pubchem (sid): 135078803
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D01539
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
grades or purity: usually 100%
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 akypo rox RLM80V
 bio-soft EC-639
2-dodecoxyethanol (peg-8)
2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
 nikkol BL-8SY
 peg-8 lauryl ether
 poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (8 mol EO average molar ratio)
 polyethylene glycol (8) lauryl ether
 polyethylene glycol (8) monolauryl ether
 polyoxyethylene (8) lauryl ether
 polyoxyethylene (8) monolauryl ether
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