Articles:
| None found yet. Try the PubMed Search. |
D-2-hydroxy-4-methylpentanoic acid
Notes:
D-Leucic acid is an alpha-hydroxycarboxylic acid present in patients affected with Short-bowel syndrome (an Inborn errors of metabolism, OMIM 175200) (PMID 9766851), and in Maple Syrup Urine Disease (MSUD, an autosomal recessive inherited metabolic disorder of branched-chain amino acid) (PMID 9766851). [HMDB]
| CAS Number: | 20312-37-2 |  3D/inchi
|
| FDA UNII: | 82AX56U3YN | |
| Nikkaji Web: | J84.593K | |
| Beilstein Number: | 1721731 | |
| MDL: | MFCD00211263 | |
| XlogP3-AA: | 0.90 (est) | |
| Molecular Weight: | 132.15924000 | |
| Formula: | C6 H12 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | colorless solid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 251.31 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.003000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 248.00 °F. TCC ( 120.10 °C. ) (est) |
| logP (o/w): | 0.522 (est) |
| Soluble in: | |
| alcohol | |
| water, 1.655e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Carbosynth |
| For experimental / research use only. |
| D-alpha-Hydroxyisocaproic acid |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| D-alpha-Hydroxyisocaproic acid ≥97% |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | information only not used for fragrances or flavors | ||
| Recommendation for (R)-leucic acid usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for (R)-leucic acid flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 439960 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| (2R)-2-hydroxy-4-methylpentanoic acid |
References:
| (2R)-2-hydroxy-4-methylpentanoic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 439960 |
| Pubchem (sid): | 36884099 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C03264 |
| HMDB (The Human Metabolome Database): | HMDB00624 |
| FooDB: | FDB022149 |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| dextro-2- | hydroxy-4-methyl pentanoic acid |
| (R)-2- | hydroxy-4-methyl valeric acid |
| (R)-2- | hydroxy-4-methyl-pentanoic acid |
| (2R)-2- | hydroxy-4-methylpentanoic acid |
| (R)-2- | hydroxy-4-methylpentanoic acid |
| D-2- | hydroxy-4-methylpentanoic acid |
| (R)-2- | hydroxy-4-methylpentanoicacid |
| (R)-2- | hydroxy-4-methylvaleric acid |
| D-2- | hydroxyisocaproate |
| (-)-2- | hydroxyisocaproic acid |
| (-)-a- | hydroxyisocaproic acid |
| (-)-alpha- | hydroxyisocaproic acid |
| (R)-alpha- | hydroxyisocaproic acid |