Articles:
vitamin E TPGS
Notes:
Vitamin E supplement, antioxidant
Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of ?-tocopherol that enables water solubility.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 9002-96-4 Tocofersolan 95% Tocofersolan is a synthetic water-soluble version of vitamin E unlike its natural counterpart which are fat soluble . It is polyethylene glycol derivative of à-tocopherol which enables it water soluble. It is used as a vitamin E supplement or to treat vi Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fat
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Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GK2339 D-alpha-Tocopherol polyethylene glycol succinate
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| CAS Number: | 9002-96-4 |  3D/inchi
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| Other(deleted CASRN): | 30999-06-5 | |
| FDA UNII: | O03S90U1F2 | |
| MDL: | MFCD00146616 | |
| XlogP3-AA: | 9.90 (est) | |
| Molecular Weight: | 574.84246000 | |
| Formula: | C35 H58 O6 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: nutrient supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white to pale brown waxy solid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 662.00 to 663.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 384.00 °F. TCC ( 195.40 °C. ) (est) |
| logP (o/w): | 9.745 (est) |
| Soluble in: | |
| water, 1.655e-007 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Tocofersolan 95%
Odor: characteristic Use: Tocofersolan is a synthetic water-soluble version of vitamin E unlike its natural counterpart which are fat soluble . It is polyethylene glycol derivative of à-tocopherol which enables it water soluble. It is used as a vitamin E supplement or to treat vi
Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fat |
| Glentham Life Sciences |
| D-alpha-Tocopherol polyethylene glycol succinate |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Tocophersolan |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| D-a-Tocopherol polyethylene glycol 1000 succinate BioXtra, water soluble vitamin E conjugate |
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 > 7000 mg/kg Journal of Agricultural and Food Chemistry. Vol. 25, Pg. 273, 1977. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | nutrient supplements | ||
| Recommendation for tocophersolan usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for tocophersolan flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS) in use for food for particular nutritional purposes. View page or View pdf | |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 71406 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 1-O-(2-hydroxyethyl)4-O-[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] butanedioate | |
| Chemidplus: | 0009002964 |
References:
| 1-O-(2-hydroxyethyl)4-O-[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] butanedioate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 71406 |
| Pubchem (sid): | 135076453 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| KEGG (GenomeNet): | D06174 |
| HMDB (The Human Metabolome Database): | HMDB34354 |
| FooDB: | FDB012716 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| butanedioic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl 2-hydroxyethyl ester | |
| 2- | hydroxyethyl 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl succinate |
| 1-O-(2- | hydroxyethyl) 4-O-[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] butanedioate |
| 1-O-(2- | hydroxyethyl)4-O-[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] butanedioate |
| poly(oxy-1,2-ethanediyl), a-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2- (4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)-1,4-dioxobutyl)-omega-hydroxy-, (2R-(2R | |
| poly(oxy-1,2-ethanediyl), a-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)-1,4-dioxobutyl)-omega-hydroxy- | |
| poly(oxy-1,2-ethanediyl), a-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)-1,4-dioxobutyl)-omega-hydroxy-, (2R-(2R* | |
| mono-(2,5,7,8- | tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl) succinate polyethylene glycol monoester |
| tocofersolan | |
| D-a- | tocopherol polyethylene glycol succinate |
| D-alpha- | tocopheryl poly(ethylene glycol) 1000 succinate |
| dextro-alpha- | tocopheryl poly(ethylene glycol) 1000 succinate |
| (+)-alpha- | tocopheryl polyethylene glycol 1000 succinate |
| TPGS | |
| vitamin E TPGS |