Articles:
(2R,4'R,8'R)-a-tocopherol
Notes:
a generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids.
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): 111815 Vitamin E
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 1406-18-4 VitaminE
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ECSA Chemicals Human Chemistry ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide. ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators. Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials. Email: Info Email: Sales Email: Trading Email: Maintenance Email: Energy Voice: +41 91 695 88 00 Fax: +41 91 695 88 01 Linkedin Youtube RSS Feed ECSA Trade ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY Products List: View Product(s): MP-005862 VITAMIN E 50 TCF TOCOPHEROL MP-022541 VITAMIN E 70 TCF TOCOPHEROL
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OQEMA With a focus on providing the highest level of service OQEMA has established itself at the forefront of the global chemical industry. The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories. Email: Contact Us: US Email: Dean Matienzo Email: Sales US Email: Dean Matienzo - Sales Manager Voice: +44 1993 843081 Fax: +44 1993 841261 US Voice: +1 973 886 3778 US Fax: +1 973 346 1106 Linkedin Website Global Distribution Product(s): Vitamin E 50% Vitamin E Oil 96%
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 22-88000 VITAMIN E 22-88002 VITAMIN E USP / EU GRADE 22-88020 VITAMIN E NATURAL
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Zanos Ltd. Distributor of Speciality Chemicals and Natural Ingredients Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry. The flavour and fragrance industry's premier source for aroma chemicals and essential oils Zanos Ltd. is a B2B supplier of aroma chemicals, speciality chemicals, natural ingredients and vitamins to a diverse range of customers. In Autumn 2020, Stort Chemicals Limited completed their acquisition of Zanos Ltd. Combining our strengths, Stort and Zanos have boosted our respective portfolios of aroma chemicals, speciality chemicals and natural ingredients. With warehousing facilities across the UK, Rotterdam and Hamburg, Zanos is perfectly positioned to dispatch product throughout Europe. Email: Contact Zanos Email: Lisa Senior Voice: +44 (0) 1565 755899 Fax: +44 (0) 1565 755799 Twitter Linkedin Latest News Products Representation Products List: View Product(s): Vitamin E 50% CWS-S
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| CAS Number: | 1406-18-4 |  3D/inchi
|
| Other(deleted CASRN): | 11105-14-9 | |
| FDA UNII: | H4N855PNZ1 | |
| Nikkaji Web: | J24.260H | |
| Beilstein Number: | 94012 | |
| XlogP3-AA: | 10.70 (est) | |
| Molecular Weight: | 430.71590000 | |
| Formula: | C29 H50 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| EU SANCO | Tocopherol-rich extract View - review |
| 184.1890 | alpha-Tocopherols View - review |
| GRN 307 | Palm oil-derived tocols with tocotrienols and a-tocopherol as the principal components View - notice PDF |
| EU SANCO | Alpha-tocopherol View - review |
| GRN 781 | Alpha-tocopherol (fruit and vegetable derived) View - notice PDF |
| JECFA Food Additive: | dl-alpha-Tocopherol Tocopherol Concentrate, mixed |
| GSFA Codex: | dl-alpha-Tocopherol (307c) Tocopherol concentrate, mixed (307b) |
| DG SANTE Food Additives: | a-tocopherol |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 485.00 to 486.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 410.00 °F. TCC ( 210.20 °C. ) (est) |
| logP (o/w): | 10.962 (est) |
| Soluble in: | |
| alcohol | |
| water, 2.978e-007 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | dietary supplements | ||
| Recommendation for vitamin E usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for vitamin E flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements[1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing aids and Materials in Contact with food (AFC) View page or View pdf | |
| Scientific Opinion on the substantiation of a health claim related to a combination of flaxseed oil and vitamin E and maintenance of the skin permeability barrier function pursuant to Article 13(5) of Regulation (EC) No 1924/2006 View page or View pdf | |
| Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for vitamin E as a-tocopherol View page or View pdf | |
| Scientific Opinion on Dietary Reference Values for vitamin E as a-tocopherol View page or View pdf | |
| Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), a-tocopherol (E 307), ?-tocopherol (E 308) and d-tocopherol (E 309) as food additives View page or View pdf | |
| Vitamin E and protection of DNA, proteins and lipids from oxidative damage: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 View page or View pdf | |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 1406-18-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 14985 |
| National Institute of Allergy and Infectious Diseases: | Data |
| (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol | |
| Chemidplus: | 0001406184 |
References:
| (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 1406-18-4 |
| Pubchem (cid): | 14985 |
| Pubchem (sid): | 134981325 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| KEGG (GenomeNet): | C02477 |
| HMDB (The Human Metabolome Database): | HMDB01893 |
| FooDB: | FDB005752 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •aquasol e (armour). capsules (tocopheryl acetate) 100 and 400 iu; drops 50 iuml; e-ferol (forest). capsules (tocopheryl acetate) 200 & 400 iu. •eprolin (lilly). capsules (tocopheryl acetate) 100 iu. •vitamin e: capsules (50, 100, 200, 400, 500, 600, 800, and 1000 iu), solution (200 unitsml in 10 ml containers), drops (10 iudrop in 15 ml containers), tablets (chewable) (100, 200, 400, 500, 800, and 1000 units), wafers (400 iu). tocopherol: capsules (100, 200, 400, and 1000 iu). tocopheryl: capsules (100, 200, and 400 iu), aquasol e (usv) capsules (30, 100, and 400 iu), drops (50 iuml), elixer (33.3 iu5 ml (alcohol 25%)). e prolin: capsules(50 and 100 mg). viterra e: capsules (100, 200, 400, and 600 iu). •oral capsules: 100 units; 200 units e-vitamin succinate (as d-alpha-tocopheryl acid succinate), forest; 400 mg e-vitamin succinate (as d-alpha-tocopheryl acid succinate), forest; vita-plus e (as d-alpha-tocopheryl acetate), scot-tussin; 600, 1000 units •capsules, water miscible: 100 unit aquasol e (as d-alpha-tocopheryl acetate; with parabens), •oil solution water miscible: 50 unitsml aquasol e drops (as d-alpha-tocopheryl acetate; with propylene glycol), astra •tablets 100, 200 units; 400 units pheryl e (as d-alpha- tocopheryl acid succinate) miller; 500, 600, 1000 units •tablets chewable 100, 200, 400 units •vitamin e is also commercially available in combination with other vitamins, minerals, protein supplements, and infant formulas. | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| buckthorn sea buckthorn fruit Search Trop Picture | |
| caper seed Search Trop Picture | |
| caper seed oil Search Trop Picture | |
| carrot plant Search Trop Picture | |
| coconut seed Search Trop Picture | |
| lettuce leaf Search Trop Picture | |
| soybean seed Search Trop Picture | |
| soybean seed oil Search Trop Picture | |
| wheat sprout Search Trop Picture |
Synonyms:
| aquasol E | |
| (2R)-3,4- | dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol |
| [2R-2R*(4R*,8R*)]-3,4- | dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol |
| [2R-[2R*(4R*,8R*)]]-3,4- | dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate |
| (2R)-3,4- | dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol |
| emipherol | |
| etamican | |
| irganox E 201 | |
| juvela E | |
| phytogermine | |
| rocavit E | |
| spavit E | |
| (R)-2,5,7,8- | tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol |
| (2R,4'R,8'R)-2,5,7,8- | tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol |
| (2R)-2,5,7,8- | tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol |
| (2R)-2,5,7,8- | tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol |
| (2R)-2,5,7,8- | tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol |
| (2R)-2,5,7,8- | tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol |
| (+)-a- | tocopherol |
| (2R,4'R,8'R)-a- | tocopherol |
| (all-R)-a- | tocopherol |
| (R,R,R)-a- | tocopherol |
| a- | tocopherol |
| RRR-a- | tocopherol |
| (2R)-2-((4R,8R)-4,8,12- | trimethyltridecyl)-2,5,7,8-tetramethylchroman-6-ol |