Articles:
methyl-5,6-dimethylbenzimidazolylcobalamin
Notes:
The name vitamin B12 is used in two different ways. In a broad sense it refers to a group of cobalt-containing compounds known as cobalamins - cyanocobalamin (an artifact formed as a result of the use of cyanide in the purification procedures), hydroxocobalamin and the two coenzyme forms of B12, methylcobalamin (MeB12) and 5-deoxyadenosylcobalamin (adenosylcobalamin - AdoB12). In a more specific way, the term B12 is used to refer to only one of these forms, cyanocobalamin, which is the principal B12 form used for foods and in nutritional supplements.
B12 cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of B12 are bacteria and archaea. The total synthesis of B12 was reported in 1973 by Robert Burns Woodward, and remains one of the classic feats of total synthesis.
Cyanocobalamin is a vitamin commonly known as vitamin B12 (or B12 for short). [HMDB]
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): MCBAUP Methylcobalamin USP MMTAUP Methylcobalamin 1Trituration On Mannitol
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 13422-55-4 Mecobalamin >98% Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation.
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Charkit Chemical Corporation The Specialty Chemical Specialists Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you. about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals. Email: Sales Voice: 203-299-3220 Fax: 203-299-1355 Facebook Twitter Linkedin Latest News Events Blog Products List: View Product(s): METHYLCOBALAMIN
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GV9033 Methylcobalamin hydrate
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| CAS Number: | 13422-55-4 |  3D/inchi
|
| Other(deleted CASRN): | 13870-88-7 | |
| FDA UNII: | BR1SN1JS2W | |
| MDL: | MFCD00082483 | |
| Molecular Weight: | 1344.40502700 | |
| Formula: | C63 H91 Co N13 O14 P | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: nutrient supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 98.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | -2.812 (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| AIDP |
| Methylcobalamin B12 98% min. |
| American International Chemical, LLC. |
| Methylcobalamin 1Trituration On Mannitol |
| American International Chemical, LLC. |
| Methylcobalamin USP |
| BOC Sciences |
| For experimental / research use only. |
| Mecobalamin >98%
Odor: characteristic Use: Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. |
| Charkit Chemical |
| METHYLCOBALAMIN |
| George Uhe Company |
| Mecobalamin |
| Glentham Life Sciences |
| Methylcobalamin hydrate |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Mecobalamin |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Methylcobalamin vitamin B12 analog |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. intraperitoneal-rat LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. intravenous-rabbit LD50 > 75 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. oral-mouse LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. intraperitoneal-mouse LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. intravenous-dog LD > 200 mg/kg Kiso to Rinsho. Clinical Report. Vol. 22, Pg. 3939, 1988. | |
| Dermal Toxicity: | |
|
subcutaneous-rat LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. subcutaneous-mouse LD50 > 5000 mg/kg Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 529, 1970. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | nutrient supplements | ||
| Recommendation for mecobalamin usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for mecobalamin flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| 5’-deoxyadenosylcobalamin and methylcobalamin as sources for Vitamin B12 added as a nutritional substance in food supplements[1] - Scientific opinion of the Scientific Panel on Food Additives and Nutrient Sources added to food View page or View pdf | |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6436232 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| carbanide;cobalt(3+);[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]1-[3-[(4Z,9Z,14Z)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3 | |
| Chemidplus: | 0013422554 |
| RTECS: | GG3745000 for cas# 13422-55-4 |
References:
| carbanide;cobalt(3+);[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]1-[3-[(4Z,9Z,14Z)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3 | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 6436232 |
| Pubchem (sid): | 135030891 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| KEGG (GenomeNet): | C06453 |
| HMDB (The Human Metabolome Database): | HMDB02274 |
| FooDB: | FDB022939 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| algobaz | |
| co-methylcobalamin | |
| cobalt-methylcobalamin | |
| cobamet | |
| cobametin | |
| hitocobamin M | |
| methycobal | |
| methyl cobalamin | |
| methyl cobalamine | |
| methyl vitamin B12 | |
| methyl-5,6-dimethylbenzimidazolylcobalamin | |
| methylcob(III)alamin | |
| methylcobal | |
| methylcobalamin | |
| methylcobaz | |
| vancomin |