sodium hyaluronate
hyaluronic acid, sodium salt
 
Notes:
a natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. it is found in the umbilical cord, in vitreous humor, in synovial fluid, in pathologic joints, in group a and c hemolytic streptococci, and in wharton's jelly. a high urinary level is found in progeria.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      SHYKKS Sodium Hyaluronate
       
  • BOC Sciences
    • BOC Sciences
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      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      9067-32-7 Hyaluronic acid sodium
      Hyaluronic Acid, Sodium Salt is sodium salt form of Hyaluronic Acid. Hyaluronic acid, a mucopolysaccharide with high-viscosity, traditionally extracted from rooster combs, but now it is mainly produced via streptococcal fermentation.
       
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      SODIUM HYALURONATE (HYALURONIC ACID)
      SODIUM HYALURONATE 1% SOLUTION
      SODIUM HYALURONATE POWDER
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      Product(s):
      MP-025091 SODIUM HYALURONATE 1.0-1.4 Mda
      MP-025326 SODIUM HYALURONATE 1.00MDA - 1.80MDA
      MP-026146 SODIUM HYALURONATE 0.2-0.4MDa
       
  • Glentham Life Sciences
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      HLC-402 Sodium Hyaluronate
      HLCFD-136 Sodium Hyaluronate
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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      Product(s):
      7133N Sodium hyaluronate Nat.
       
Synonyms   Articles   Notes   Search
CAS Number: 9067-32-7Picture of molecule3D/inchi
Other(deleted CASRN): 34448-35-6
FDA UNII: YSE9PPT4TH
MDL: MFCD01773053
Molecular Weight: 799.64404928
Formula: C28 H44 N2 Na O23 +
NMR Predictor: Predict (works with chrome or firefox)
Category: dietary supplements: EFSA: cannot be assessed.
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: white powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 1274.00 to 1275.00 °C. @ 760.00 mm Hg (est)
Flash Point: 1336.00 °F. TCC ( 724.50 °C. ) (est)
logP (o/w): -6.623 (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: humectants
skin conditioning
Synonyms   Articles   Notes   Search   Top
Suppliers:
AIDP
Hyaluronic Acid Sodium 99% HA 99% min.
American International Chemical, LLC.
Sodium Hyaluronate
AuNutra® Industries
Hyaluronic Acid Sodium
BOC Sciences
For experimental / research use only.
Hyaluronic acid sodium
Odor: characteristic
Use: Hyaluronic Acid, Sodium Salt is sodium salt form of Hyaluronic Acid. Hyaluronic acid, a mucopolysaccharide with high-viscosity, traditionally extracted from rooster combs, but now it is mainly produced via streptococcal fermentation.
Charkit Chemical
SODIUM HYALURONATE (HYALURONIC ACID)
Charkit Chemical
SODIUM HYALURONATE 1% SOLUTION
Charkit Chemical
SODIUM HYALURONATE POWDER
Chemical-navi - Nikkol
SODIUM HYALURONATE POWDER (CHA)
Contipro
Hyaluronan Oligosaccharides
Odor: characteristic
Use: Sodium hyaluronate oligosaccharides (hyaluronan oligomers) are non-sulphated glycosaminoglycans. The structure is given by an enzyme used for the digestion that cleaves selectively β (1?4) glycosidic bonds between disaccharide units of sodium hyaluronate. The enzymatic digestion is followed by chromatographic separation when the pure, size-uniformed species are obtained.
Contipro
Sodium hyaluronate LMW
Odor: characteristic
Use: Sodium hyaluronate (hyaluronan, sodium salt of hyaluronic acid) is a non-sulphated glycosaminoglycan, a naturally occuring polysaccharide.
Contipro
Sodium Hyaluronate
Odor: characteristic
Use: Sodium hyaluronate is a non-sulphated glycosaminoglycan, a naturally occuring polysaccharide.
ECSA Chemicals
SODIUM HYALURONATE 0.2-0.4MDa
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
SODIUM HYALURONATE 1.0-1.4 Mda
ECSA Chemicals
SODIUM HYALURONATE 1.00MDA - 1.80MDA
Glentham Life Sciences
Hyaluronic acid sodium salt, m.w. 1.0 - 1.5 MDa
Glentham Life Sciences
Hyaluronic acid sodium salt, m.w. 3,000 - 5,000
Glentham Life Sciences
Hyaluronic acid sodium salt, m.w. 30,000 - 50,000
Glentham Life Sciences
Hyaluronic acid sodium salt, m.w. 50,000 - 100,000
Jiangyin Healthway
Sodium Hyaluronate
New functional food ingredients
Jiangyin Healthway
Sodium Hyaluronate
Lipo Chemicals
Lipo® Hyaluronic Acid - 1% Solution
Odor: characteristic
Use: Hyaluronic Acid (HA) is a naturally-occurring polyanionic polysaccharide. It is present in the intercellular domains of connective tissues and especially in the skin. Because of its unique rheological, viscoelastic and hygroscopic properties, HA plays a key role in protecting and stabilizing the skin at the cellular level.
Lipo Chemicals
Lipo® Hyaluronic Acid
Odor: characteristic
Use: Hyaluronic Acid (HA) is a naturally-occurring polyanionic polysaccharide. It is present in the intercellular domains of connective tissues and especially in the skin. Because of its unique rheological, viscoelastic and hygroscopic properties, HA plays a key role in protecting and stabilizing the skin at the cellular level.
Lipo Chemicals
Orgasol® Hydra+
Odor: characteristic
Use: Orgasol® Hydra+ brings immediate sensorial and visual effects combined with long-term efficacy. It offers a perfect velvet finish and an immediate optical smoothing effect to color cosmetics, turning daily makeup application into a moisturizing treatment. Orgasol® Hydra+ delivers hyaluronic acid to the skin.
Lipotec USA
Actiglide®
Lipotec USA
Actimoist® Bio 1
Lipotec USA
Actimoist® Bio 2
M.C.Biotec
Sodium Hyaluronate
Maypro Industries
Sodium Hyaluronate
Meafo
For experimental / research use only.
Sodium Hyaluronate 95%
Santa Cruz Biotechnology
For experimental / research use only.
Hyaluronic Acid, Sodium Salt
Sigma-Aldrich: Sigma
For experimental / research use only.
Hyaluronic acid sodium salt
Solabia
Hyaluronic Acid BT
Odor: characteristic
Use: Given its high molecular weight, Hyaluronic Acid BT maintains an optimum level of hydration.
Spec-Chem Industry
SpecKareTM HA (Sodium Hyaluronate)
TRI-K Industries
HyaClear® Solution
Odor: characteristic
Use: A crystal clear solution of 1% sodium hyaluronate in water, HyaClear™ Solution helps skin retain moisture, decreases skin roughness, improves barrier function and decreases desquamation for smoother, healthier looking skin. It has a stable viscosity, clarity and pH at high formulating temperatures for easy formulation.
TRI-K Industries
Sodium Hyaluronate Powder
Odor: characteristic
Use: A natural mucopolysaccharide produced by an all-natural fermentation and purification process. This natural humectant preserves skin’s elasticity and firmness.
United International
Sodium hyaluronate Nat.
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 800 mg/kg
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

intraperitoneal-rat LD50  1770 mg/kg
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BLOOD: NORMOCYTIC ANEMIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

oral-rabbit LD50  > 1000 mg/kg
Drugs in Japan Vol. -, Pg. 849, 1990.

intraperitoneal-rabbit LD50  1820 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: NORMOCYTIC ANEMIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

oral-mouse LD50  > 2400 mg/kg
Drugs in Japan Vol. -, Pg. 849, 1990.

intraperitoneal-mouse LD50  1500 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 1013, 1984.

Dermal Toxicity:
subcutaneous-rat LD50 > 4000 mg/kg
BEHAVIORAL: ATAXIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

subcutaneous-rabbit LD50 > 2000 mg/kg
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

subcutaneous-mouse LD50 > 4000 mg/kg
BEHAVIORAL: ATAXIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

subcutaneous-dog LD50 > 50 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: dietary supplements: EFSA: cannot be assessed.
Recommendation for sodium hyaluronate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium hyaluronate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Inability to assess the safety of sodium hyaluronate added for nutritional purposes as a source of sodium in food supplements and the bioavailability of sodium from this source, based on the supporting dossier [1]
View page or View pdf
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
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Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 3084049
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carbo
Chemidplus: 0009067327
RTECS: MT7250000 for cas# 9067-32-7
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References:
 sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carbo
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 3084049
Pubchem (sid): 135232288
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FDA Listing of Food Additive Status: View
MedlinePlusSupp: View
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 actiglide
 actimoist Bio 1
 actimoist Bio 2
 chlamyhyaluronic acid sodium salt
 chronosphere hyaluronic
 hyaluronate sodium
 hyaluronic acid sodium
 hyaluronic acid, sodium salt
 orgasol hydra+
 sodium hyaluronate 1 solution macronan S
 sodium hyaluronate LMW
 sodium hyaluronate macronan PF
 sodium hyaluronate macronan-P
 sodium hyaluronate powder (CHA)
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Articles:
PubMed: Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation.
PubMed: Systematical method for polyacrylamide and residual acrylamide detection in cosmetic surgery products and example application.
PubMed: [Evaluation of postsurgical adhesion prevention using different formulated sodium hyaluronate membranes].
PubMed: [Ideas about registration for sodium hyaluronate facial derma fillers].
PubMed: Genotoxicity, acute and subchronic toxicity studies in rats of a rooster comb extract rich in sodium hyaluronate.
PubMed: Demonstration of efficacy in the treatment of dry eye disease with 0.18% sodium hyaluronate ophthalmic solution (vismed, rejena).
PubMed: Nonheme iron absorption in young women is not influenced by purified sulfated and unsulfated glycosaminoglycans.
PubMed: Intra-articular hyaluronans: a review of product-specific safety profiles.
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