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Category: dietary supplements: EFSA: cannot be assessed.
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white powder (est) |
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 1274.00 to 1275.00 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 1336.00 °F. TCC ( 724.50 °C. ) (est)
|
| logP (o/w): | -6.623 (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| AIDP |
| Hyaluronic Acid Sodium 99% HA 99% min.
|
| American International Chemical, LLC. |
| Sodium Hyaluronate
|
| AuNutra® Industries |
| Hyaluronic Acid Sodium
|
| BOC Sciences |
| For experimental / research use only. |
| Hyaluronic acid sodium
Odor: characteristic Use: Hyaluronic Acid, Sodium Salt is sodium salt form of Hyaluronic Acid. Hyaluronic acid, a mucopolysaccharide with high-viscosity, traditionally extracted from rooster combs, but now it is mainly produced via streptococcal fermentation. |
| Charkit Chemical |
| SODIUM HYALURONATE (HYALURONIC ACID)
|
| Charkit Chemical |
| SODIUM HYALURONATE 1% SOLUTION
|
| Charkit Chemical |
| SODIUM HYALURONATE POWDER
|
| Chemical-navi - Nikkol |
| SODIUM HYALURONATE POWDER (CHA)
|
| Contipro |
| Hyaluronan Oligosaccharides
Odor: characteristic Use: Sodium hyaluronate oligosaccharides (hyaluronan oligomers) are non-sulphated glycosaminoglycans. The structure is given by an enzyme used for the digestion that cleaves selectively β (1?4) glycosidic bonds between disaccharide units of sodium hyaluronate. The enzymatic digestion is followed by chromatographic separation when the pure, size-uniformed species are obtained. |
| Contipro |
| Sodium hyaluronate LMW
Odor: characteristic Use: Sodium hyaluronate (hyaluronan, sodium salt of hyaluronic acid) is a non-sulphated glycosaminoglycan, a naturally occuring polysaccharide. |
| Contipro |
| Sodium Hyaluronate
Odor: characteristic Use: Sodium hyaluronate is a non-sulphated glycosaminoglycan, a naturally occuring polysaccharide. |
| ECSA Chemicals |
| SODIUM HYALURONATE 0.2-0.4MDa
|
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ECSA Chemicals |
| SODIUM HYALURONATE 1.0-1.4 Mda
|
| ECSA Chemicals |
| SODIUM HYALURONATE 1.00MDA - 1.80MDA
|
| Glentham Life Sciences |
| Hyaluronic acid sodium salt, m.w. 1.0 - 1.5 MDa
|
| Glentham Life Sciences |
| Hyaluronic acid sodium salt, m.w. 3,000 - 5,000
|
| Glentham Life Sciences |
| Hyaluronic acid sodium salt, m.w. 30,000 - 50,000
|
| Glentham Life Sciences |
| Hyaluronic acid sodium salt, m.w. 50,000 - 100,000
|
| Jiangyin Healthway |
| Sodium Hyaluronate
|
| New functional food ingredients |
| Jiangyin Healthway |
| Sodium Hyaluronate
|
| Lipo Chemicals |
| Lipo® Hyaluronic Acid - 1% Solution
Odor: characteristic Use: Hyaluronic Acid (HA) is a naturally-occurring polyanionic polysaccharide. It is present in the intercellular domains of connective tissues and especially in the skin. Because of its unique rheological, viscoelastic and hygroscopic properties, HA plays a key role in protecting and stabilizing the skin at the cellular level. |
| Lipo Chemicals |
| Lipo® Hyaluronic Acid
Odor: characteristic Use: Hyaluronic Acid (HA) is a naturally-occurring polyanionic polysaccharide. It is present in the intercellular domains of connective tissues and especially in the skin. Because of its unique rheological, viscoelastic and hygroscopic properties, HA plays a key role in protecting and stabilizing the skin at the cellular level. |
| Lipo Chemicals |
| Orgasol® Hydra+
Odor: characteristic Use: Orgasol® Hydra+ brings immediate sensorial and visual effects combined with long-term efficacy. It offers a perfect velvet finish and an immediate optical smoothing effect to color cosmetics, turning daily makeup application into a moisturizing treatment. Orgasol® Hydra+ delivers hyaluronic acid to the skin. |
| Lipotec USA |
| Actiglide®
|
| Lipotec USA |
| Actimoist® Bio 1
|
| Lipotec USA |
| Actimoist® Bio 2
|
| M.C.Biotec |
| Sodium Hyaluronate
|
| Maypro Industries |
| Sodium Hyaluronate
|
| Meafo |
| For experimental / research use only. |
| Sodium Hyaluronate 95%
|
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Hyaluronic Acid, Sodium Salt
|
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Hyaluronic acid sodium salt
|
| Solabia |
| Hyaluronic Acid BT
Odor: characteristic Use: Given its high molecular weight, Hyaluronic Acid BT maintains an optimum level of hydration. |
| Spec-Chem Industry |
| SpecKareTM HA (Sodium Hyaluronate)
|
| TRI-K Industries |
| HyaClear® Solution
Odor: characteristic Use: A crystal clear solution of 1% sodium hyaluronate in water, HyaClear™ Solution helps skin retain moisture, decreases skin roughness, improves barrier function and decreases desquamation for smoother, healthier looking skin. It has a stable viscosity, clarity and pH at high formulating temperatures for easy formulation. |
| TRI-K Industries |
| Sodium Hyaluronate Powder
Odor: characteristic Use: A natural mucopolysaccharide produced by an all-natural fermentation and purification process. This natural humectant preserves skin’s elasticity and firmness. |
| United International |
| Sodium hyaluronate Nat.
|
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 800 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
intraperitoneal-rat LD50 1770 mg/kg SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
BLOOD: NORMOCYTIC ANEMIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
oral-rabbit LD50 > 1000 mg/kg Drugs in Japan Vol. -, Pg. 849, 1990.
intraperitoneal-rabbit LD50 1820 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BLOOD: NORMOCYTIC ANEMIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
oral-mouse LD50 > 2400 mg/kg Drugs in Japan Vol. -, Pg. 849, 1990.
intraperitoneal-mouse LD50 1500 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
SKIN AND APPENDAGES (SKIN): HAIR: OTHER Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 1013, 1984.
|
| Dermal Toxicity: |
subcutaneous-rat LD50 > 4000 mg/kg BEHAVIORAL: ATAXIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
subcutaneous-rabbit LD50 > 2000 mg/kg SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
subcutaneous-mouse LD50 > 4000 mg/kg BEHAVIORAL: ATAXIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
subcutaneous-dog LD50 > 50 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | dietary supplements: EFSA: cannot be assessed. |
| Recommendation for sodium hyaluronate usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for sodium hyaluronate flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Inability to assess the safety of sodium hyaluronate added for nutritional purposes as a source of sodium in food supplements and the bioavailability of sodium from this source, based on the supporting dossier [1] View page or View pdf |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 3084049 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carbo |
| Chemidplus: | 0009067327 |
| RTECS: | MT7250000 for cas# 9067-32-7 |
References:
| | sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carbo |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 3084049 |
| Pubchem (sid): | 135232288 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | actiglide | | | actimoist Bio 1 | | | actimoist Bio 2 | | | chlamyhyaluronic acid sodium salt | | | chronosphere hyaluronic | | | hyaluronate sodium | | | hyaluronic acid sodium | | | hyaluronic acid, sodium salt | | | orgasol hydra+ | | | sodium hyaluronate 1 solution macronan S | | | sodium hyaluronate LMW | | | sodium hyaluronate macronan PF | | | sodium hyaluronate macronan-P | | | sodium hyaluronate powder (CHA) |
Articles:
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