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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white needles or prisms (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 283.00 °C. @ 760.00 mm Hg (est)
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| Boiling Point: | 273.00 to 276.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 1.760000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 284.00 °F. TCC ( 139.80 °C. ) (est)
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| logP (o/w): | 0.235 (est) |
| Soluble in: |
| | water, 2.82E+04 mg/L @ 16C (exp) | | | water, 9357 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-human TDLo 500 mg/kg/5W-I GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Journal of the American College of Toxicology. Vol. 1(3), Pg. 124, 1982.
intraperitoneal-rat LD50 5452 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for dextro-phenyl alanine usage levels up to: | | | not for fragrance use.
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| Recommendation for dextro-phenyl alanine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (2R)-2- | amino-3-phenylpropanoic acid | | (R)-2- | amino-3-phenylpropionic acid | | D-a- | amino-b-phenylpropionic acid | | D- | fenylalanine | | (R)-(+)- | phenyl alanine | | (R)- | phenylalanine | | (R)-(+)- | phenylalanine | | D- | phenylalanine | | D-(+)- | phenylalanine | | D- | phenylalaninol | | | sabiden |
Articles:
| PubMed: | Flavonolignans and Other Constituents from Lepidium meyenii with Activities in Anti-inflammation and Human Cancer Cell Lines. |
| PubMed: | Effects of conversion of the zinc-binding motif sequence of thermolysin, HEXXH, to that of dipeptidyl peptidase III, HEXXXH, on the activity and stability of thermolysin. |
| PubMed: | Characterization of ergothionase from Burkholderia sp. HME13 and its application to enzymatic quantification of ergothioneine. |
| PubMed: | Relative fasting bioavailability of two formulations of nateglinide 60 mg in healthy male Chinese volunteers: an open-label, randomized-sequence, single-dose, two-way crossover study. |
| PubMed: | The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. |
| PubMed: | [Intestinal absorption and secretion mechanism of carboxylate drugs]. |
| PubMed: | Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. |
| PubMed: | Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length. |
| PubMed: | Exenatide: a new option for the treatment of type 2 diabetes. |
| PubMed: | Gas chromatographic determination and mechanism of formation of D-amino acids occurring in fermented and roasted cocoa beans, cocoa powder, chocolate and cocoa shell. |
| PubMed: | Performance of D-amino acid oxidase in presence of ionic liquids. |
| PubMed: | Characterization of Gly-D-Phe, Gly-L-Leu, and D-Phe as affinity ligands to thermolysin. |
| PubMed: | A new strategy for the selective determination of D-amino acids: enzymatic and chemical modifications for pre-column derivatization. |
| PubMed: | Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues. |
| PubMed: | The tripeptide FEG ameliorates systemic inflammatory responses to rat intestinal anaphylaxis. |
| PubMed: | Sweetener preference of C57BL/6ByJ and 129P3/J mice. |
| PubMed: | Importance of postprandial glucose control. |
| PubMed: | [Pharmacological properties of nateglinide, rapid-onset/short-duration insulinotropic agent, in the treatment of type 2 diabetes]. |
| PubMed: | Stabilization of D-amino acid oxidase and catalase in permeabilized Rhodotorula gracilis cells and its application for the preparation of alpha-ketoacids*. |
| PubMed: | Chemistry, nutrition, and microbiology of D-amino acids. |
| PubMed: | Calcium-deprived rats avoid sweet compounds. |
| PubMed: | Effect of food on the bioavailability of SDZ DJN 608, an oral hypoglycemic agent, from a tablet and a liquid-filled capsule in the dog. |
| PubMed: | Suppression of meal size by intestinal nutrients is eliminated by celiac vagal deafferentation. |
| PubMed: | The genetic basis of preference for sweet substances among inbred strains of mice: preference ratio phenotypes and the alleles of the Sac and dpa loci. |
| PubMed: | Separation of amino-acid enantiomers using micellar-enhanced ultrafiltration. |
| PubMed: | Formation, nutritional value, and safety of D-amino acids. |
| PubMed: | Treatment of hyperactive children with D-phenylalanine. |
| PubMed: | The availability of D-phenylalanine and DL-phenylalanine. |
| PubMed: | The nutritive value and safety of D-phenylalanine and D-tyrosine in mice. |
| PubMed: | Racemization of aspartic acid and phenylalanine in the sweetener aspartame at 100 degrees C. |
| PubMed: | Feeding, drinking, urine osmolality in DI Brattleboro rats: changes by morphine, naloxone, D-amino acids, prolyl-leucyl-glycinamide (PLG). |
| PubMed: | Modulation of deprivation-induced food intake by D-phenylalanine. |
| PubMed: | The effect of gastric loads of sugars and amino acids on milk intake of suckling pigs. |
| PubMed: | Ontogeny of cholecystokinin satiety in rats. |
| PubMed: | Cholecystokinin and satiety in rats and rhesus monkeys. |
| PubMed: | Cholecystokinin-decreased food intake in rhesus monkeys. |
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