Articles:
D-hydroxybutanedioic acid
Notes:
This enantiomer of rare occurrence; reported from fruits and leaves of Hibiscus sabdariffa (roselle) although there are many more isolations of malic acid with no opt. rotn. given and some may be of the R-form
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 13-03190 D-MALIC ACID
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| CAS Number: | 636-61-3 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 211-262-2 | |
| FDA UNII: | P750Y95K96 | |
| Nikkaji Web: | J14.674I | |
| Beilstein Number: | 1723540 | |
| MDL: | MFCD00004245 | |
| XlogP3: | -1.30 (est) | |
| Molecular Weight: | 134.08782000 | |
| Formula: | C4 H6 O5 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: food additive
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 98.00 to 102.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 306.00 to 307.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000007 mmHg @ 25.00 °C. (est) |
| Flash Point: | 308.00 °F. TCC ( 153.40 °C. ) (est) |
| logP (o/w): | -1.370 (est) |
| Soluble in: | |
| water, 3.64E+05 mg/L @ 20 °C (exp) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Aston Chemical |
| For experimental / research use only. |
| (R)-Malic Acid |
| BOC Sciences |
| For experimental / research use only. |
| D-(+)-Malic acid ≥98%, ≥95%e.e. |
| Penta International |
| D-MALIC ACID |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| D-(+)-Malic acid |
| Sigma-Aldrich |
| For experimental / research use only. |
| D-(+)-Malic acid unnatural form, ≥97.0% (T) |
| TCI AMERICA |
| For experimental / research use only. |
| D-(+)-Malic Acid >98.0%(GC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rabbit LDLo 5500 mg/kg Industrial and Engineering Chemistry. Vol. 15, Pg. 628, 1923. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | food additive | ||
| Recommendation for dextro-malic acid usage levels up to: | |||
| not for fragrance use. | |||
Safety References:
| EPI System: | View |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 92824 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| (2R)-2-hydroxybutanedioic acid | |
| Chemidplus: | 0000636613 |
| RTECS: | ON7260000 for cas# 636-61-3 |
References:
| (2R)-2-hydroxybutanedioic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 92824 |
| Pubchem (sid): | 135050551 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C00497 |
| HMDB (The Human Metabolome Database): | HMDB31518 |
| FooDB: | FDB008115 |
| Export Tariff Code: | 2918.19.6000 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| roselle fruit Search Trop Picture |
Synonyms:
| D-(+)- | apple acid |
| butanedioic acid, 2-hydroxy-, (2R)- | |
| (R)-2- | hydroxy-succinic acid |
| (R)-2- | hydroxybutane dioic acid |
| (2R)-2- | hydroxybutanedioic acid |
| (R)- | hydroxybutanedioic acid |
| D- | hydroxybutanedioic acid |
| (2R)-2- | hydroxysuccinic acid |
| (R)-(+)- | hydroxysuccinic acid |
| (R)-2- | hydroxysuccinic acid |
| (+)-D- | malic acid |
| (R)- | malic acid |
| (R)-(+)- | malic acid |
| D- | malic acid |
| D-(+)- | malic acid |
| R- | malic acid |
| malic acid, D- |