Articles:
vitaplex E
Notes:
a natural tocopherol and one of the most potent antioxidant tocopherols. it exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus. it has four methyl groups on the 6-chromanol nucleus. the natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture. Constit. of many vegetable oils such as soya and sunflower oils. Dietary supplement and nutrient. Nutriceutical with anticancer and antioxidant props. Added to fats and oils to prevent rancidity. The naturally-occurring tocopherol is a single stereoisomer; synthetic forms are a mixt. of all eight possible isomers
Alpha-tocopherol is traditionally recognized as the most active form of vitamin E in humans, and is a powerful biological antioxidant.
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): NE2TJO Natural Vitamin E Alcohol 1000IU Light USP
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 59-02-9 a-Tocophenol
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Jiangyin Healthway International Trade Co., Ltd Independent Ingredients Supplier We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals. Email: Info Email: Sales Voice: 86-510-86023169 Fax: 86-510-86023170 Mobile 0086-13093133011 Services Biochemical Natural Food Colour New functional food ingredients Product(s): 110594 Natural Vitamin E
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OQEMA With a focus on providing the highest level of service OQEMA has established itself at the forefront of the global chemical industry. The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories. Email: Contact Us: US Email: Dean Matienzo Email: Sales US Email: Dean Matienzo - Sales Manager Voice: +44 1993 843081 Fax: +44 1993 841261 US Voice: +1 973 886 3778 US Fax: +1 973 346 1106 Linkedin Website Global Distribution Product(s): Vitamin E
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| CAS Number: | 59-02-9 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 200-412-2 | |
| FDA UNII: | N9PR3490H9 | |
| Nikkaji Web: | J529.413D | |
| Beilstein Number: | 4712525 | |
| MDL: | MFCD00072045 | |
| XlogP3-AA: | 10.70 (est) | |
| Molecular Weight: | 430.71590000 | |
| Formula: | C29 H50 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: antioxidants and preservatives for fragrance and flavor
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| 184.1890 | alpha-Tocopherols View - review |
| GRN 307 | Palm oil-derived tocols with tocotrienols and a-tocopherol as the principal components View - notice PDF |
| EU SANCO | Tocopherol-rich extract View - review |
| EU SANCO | Alpha-tocopherol View - review |
| GRN 781 | Alpha-tocopherol (fruit and vegetable derived) View - notice PDF |
| JECFA Food Additive: | dl-alpha-Tocopherol Tocopherol Concentrate, mixed d-alpha-Tocopherol Concentrate |
| GSFA Codex: | dl-alpha-Tocopherol (307c) Tocopherol concentrate, mixed (307b) d-alpha-Tocopherol (307a) |
| DG SANTE Food Additives: | alpha-tocophenol |
| DG SANTE Food Contact Materials: | alpha-tocophenol |
Physical Properties:
| Appearance: | pale yellow to red clear liquid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 2.00 to 3.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 482.00 to 485.00 °C. @ 760.00 mm Hg |
| Flash Point: | 410.00 °F. TCC ( 210.00 °C. ) |
| logP (o/w): | 10.962 (est) |
| Shelf Life: | 12.00 month(s) or longer if stored properly. |
| Storage: | refrigerate in tightly sealed containers. |
| Soluble in: | |
| alcohol | |
| water, 2.978e-007 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants fragrance skin conditioning |
Suppliers:
| ADM |
| NOVATOL 1490 |
| ADM |
| NOVATOL 5-67 NON GMO |
| ADM |
| NOVATOL 5-67
Flavor: characteristic NOVATOL 5-67 is a clear, amber color, viscous oil having a slight characteristic vegetable oil aroma and a mild taste. NOVATOL 5-67 may oxidize upon exposure to air and light, resulting in gradual darkening. Nitrogen blanketing and protection from light, from heat, from transition metals and from alkalis are recommended. NOVATOL 5-67 is a concentrated form of natural source d-alpha-tocopherol derived from edible vegetable oils. Research indicates that the human body prefers the natural source Vitamin E, such as NOVATOL 5-67, over the synthetic forms. Moreover, based on the Food and Nutrition Board Expert Panel report on Vitamin E, d-alpha-tocopherol has twice the activity of synthetic forms, which means that natural Vitamin E is 100% more effective. (Dietary Reference Intakes For Vitamin C, Vitamin E, Selenium, and Carotenoids. 2000. Vitamin E , National Academy Press, Washington, D.C.,186-283.) NOVATOL 5-67 is an essential nutrient and dietary supplement widely used in softgel capsules and liquid preparations. |
| ADM |
| NOVATOL 5-87
Flavor: characteristic NOVATOL 5-87 is a clear, amber color, viscous oil having a slight characteristic vegetable oil aroma and a mild taste. NOVATOL 5-87 may oxidize upon exposure to air and light, resulting in gradual darkening. Nitrogen blanketing and protection from light, from heat, from transition metals and from alkalis are recommended. NOVATOL 5-87 is a concentrated form of natural source d-alpha-tocopherol derived from edible vegetable oils. Research indicates that the human body prefers the natural source Vitamin E, such as NOVATOL 5-87, over the synthetic forms. Moreover, based on the Food and Nutrition Board Expert Panel report on Vitamin E, d-alpha-tocopherol has twice the activity of synthetic forms, which means that natural Vitamin E is 100% more effective. (Dietary Reference Intakes For Vitamin C, Vitamin E, Selenium, and Carotenoids.2000. Vitamin E, National Academy Press, Washington, D.C., 186-283.) NOVATOL 5-87 is an essential nutrient and dietary supplement widely used in softgel capsules and liquid preparations. |
| ADM |
| NOVATOL HPMC
Flavor: characteristic NOVATOL HPMC has little to no taste or odor and is a white to off-white crystalline powder. d-Alpha-Tocopherol is the form of tocopherol that is better retained in human tissues. It is the only form of alpha-tocopherol found in nature. The low viscosity and high concentration make d-alpha tocopherol ideal for soft gel capsules. |
| ADM |
| NOVATOL REGULAR GRADE
Flavor: characteristic NOVATOL REGULAR GRADE has little to no taste or odor and is a white to off-white crystalline powder. d-Alpha-Tocopherol is the form of tocopherol that is better retained in human tissues. It is the only form of alpha-tocopherol found in nature. The low viscosity and high concentration make d-alpha tocopherol ideal for soft gel capsules. |
| Alfa Biotechnology |
| For experimental / research use only. |
| Vitamin E 98% |
| Ambles Nature et Chimie |
| ALPHA TOCOPHEROL NAT |
| American International Chemical, LLC. |
| Natural Vitamin E Alcohol 1000IU Light USP |
| BOC Sciences |
| For experimental / research use only. |
| a-Tocophenol |
| Jiangyin Healthway |
| Natural Vitamin E |
| New functional food ingredients |
| OQEMA |
| Vitamin E |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| (+)-a-Tocopherol from vegetable oil, Type V, ∼1000 IU/g |
| Sinoway Industrial |
| For experimental / research use only. |
| Natural vitamin E |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
|
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | antioxidants and preservatives for fragrance and flavor | ||
| Recommendation for alpha-tocophenol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for alpha-tocophenol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Inability to assess the safety of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol added for nutritional purposes as sources of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl- tocotrienol in food supplements and the bioavailability of beta-, gamma-, delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol from the different sources, based on the supporting dossiers [1] View page or View pdf | |
| Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements[1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing aids and Materials in Contact with food (AFC) View page or View pdf | |
| Scientific Opinion on the safety and efficacy of tocopherol-rich extracts of natural origin, tocopherol-rich extracts of natural origin/delta rich, synthetic tocopherol for all animal species View page or View pdf | |
| Scientific Opinion on the safety and efficacy of synthetic alpha-tocopherol for all animal species View page or View pdf | |
| Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for vitamin E as a-tocopherol View page or View pdf | |
| Scientific Opinion on Dietary Reference Values for vitamin E as a-tocopherol View page or View pdf | |
| Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), a-tocopherol (E 307), ?-tocopherol (E 308) and d-tocopherol (E 309) as food additives View page or View pdf | |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 59-02-9 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6033 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| (2S)-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol | |
| Chemidplus: | 0000059029 |
| RTECS: | DJ2900000 for cas# 59-02-9 |
References:
| (2S)-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 59-02-9 |
| Pubchem (cid): | 6033 |
| Pubchem (sid): | 134972125 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| Metabolomics Database: | Search |
| KEGG (GenomeNet): | C02477 |
| HMDB (The Human Metabolome Database): | HMDB01893 |
| FooDB: | FDB000565 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| antioxidants |
Occurrence (nature, food, other): note
| almond seed Search Trop Picture | |
| anise leaf Search Trop Picture | |
| anise root Search Trop Picture | |
| anise tissue culture Search Trop Picture | |
| apple fruit Search Trop Picture | |
| avocado fruit Search Trop Picture | |
| banana hull husk Search Trop Picture | |
| barley Search Trop Picture | |
| barley leaf Search Trop Picture | |
| barley root Search Trop Picture | |
| barley seed Search Trop Picture | |
| barley sprout Search Trop Picture | |
| barley tissue culture Search Trop Picture | |
| bean black bean fruit Search Trop Picture | |
| bean black bean leaf Search Trop Picture | |
| bean field bean fruit Search Trop Picture | |
| bean field bean leaf Search Trop Picture | |
| beet leaf Search Trop Picture | |
| beet root Search Trop Picture | |
| blueberry fruit Search Trop Picture | |
| broccoli asparagus broccoli leaf Search Trop Picture | |
| brussel sprout leaf Search Trop Picture | |
| cabbage leaf Search Trop Picture | |
| cantaloupe fruit Search Trop Picture | |
| caraway Search Trop Picture | |
| cardamom seed Search Trop Picture | |
| carrot leaf Search Trop Picture | |
| carrot root Search Trop Picture | |
| castor oil Search Trop Picture | |
| celery leaf Search Trop Picture | |
| celery seed Search Trop Picture | |
| celery shoot Search Trop Picture | |
| cherry sour cherry fruit Search Trop Picture | |
| coconut seed Search Trop Picture | |
| coconut seed oil Search Trop Picture | |
| coffee bean Search Trop Picture | |
| coriander Search Trop Picture | |
| corn Search Trop Picture | |
| corn fruit Search Trop Picture | |
| corn oil Search Trop Picture | |
| corn seed Search Trop Picture | |
| corn seed oil Search Trop Picture | |
| cotton levant cotton seed oil Search Trop Picture | |
| cranberry fruit Search Trop Picture | |
| cress garden cress leaf Search Trop Picture | |
| cress garden cress oil Search Trop Picture | |
| cucumber fruit Search Trop Picture | |
| currant black currant fruit Search Trop Picture | |
| currant red currant fruit Search Trop Picture | |
| dandelion leaf Search Trop Picture | |
| dill leaf Search Trop Picture | |
| evening-primrose seed Search Trop Picture | |
| fennel Search Trop Picture | |
| flax oil Search Trop Picture | |
| flax seed oil Search Trop Picture | |
| garlic bulb Search Trop Picture | |
| grape Search Trop Picture | |
| grape fruit Search Trop Picture | |
| guava pineapple guava Search Trop Picture | |
| hazelnut nut Search Trop Picture | |
| hazelnut oil Search Trop Picture | |
| hazelnut seed oil Search Trop Picture | |
| kale siberian kale Search Trop Picture | |
| leek wild leek plant Search Trop Picture | |
| lettuce fruit Search Trop Picture | |
| lychee Search Trop Picture | |
| mandarin fruit Search Trop Picture | |
| marango seed Search Trop Picture | |
| mustard field mustard oil Search Trop Picture | |
| oat seed Search Trop Picture | |
| okra oil Search Trop Picture | |
| okra seed Search Trop Picture | |
| okra seed oil Search Trop Picture | |
| olive oil Search Trop Picture | |
| onion bulb Search Trop Picture | |
| onion seed oil Search Trop Picture | |
| orange fruit Search Trop Picture | |
| oregano leaf Search Trop Picture | |
| palm kernal oil Search PMC Picture | |
| palm oil Search PMC Picture | |
| papaya leaf Search Trop Picture | |
| parsley leaf Search Trop Picture | |
| peach fruit Search Trop Picture | |
| peanut nut Search Trop Picture | |
| peanut oil Search Trop Picture | |
| peanut seed oil Search Trop Picture | |
| pear fruit Search Trop Picture | |
| pepper bell pepper fruit Search Trop Picture | |
| pepper black pepper fruit Search Trop Picture | |
| pepper black pepper sap Search Trop Picture | |
| pepper black pepper seed Search Trop Picture | |
| peppermint leaf Search Trop Picture | |
| pineapple fruit Search Trop Picture | |
| pistachio nut Search Trop Picture | |
| plum fruit Search Trop Picture | |
| potato tuber Search Trop Picture | |
| raspberry red raspberry fruit Search Trop Picture | |
| rhubarb leaf Search Trop Picture | |
| rhubarb plant Search Trop Picture | |
| rice Search Trop Picture | |
| rice bran oil Search Trop Picture | |
| rice seed Search Trop Picture | |
| roselle seed Search Trop Picture | |
| rosemary leaf Search Trop Picture | |
| rye Search Trop Picture | |
| safflower oil Search Trop Picture | |
| safflower seed oil Search Trop Picture | |
| sesame oil Search Trop Picture | |
| sesame seed Search Trop Picture | |
| sesame seed oil Search Trop Picture | |
| soybean cotyledon Search Trop Picture | |
| soybean leaf Search Trop Picture | |
| soybean oil Search Trop Picture | |
| soybean seed Search Trop Picture | |
| soybean seed coat Search Trop Picture | |
| soybean seed oil Search Trop Picture | |
| spinach leaf Search Trop Picture | |
| sunflower oil Search Trop Picture | |
| sunflower seed oil Search Trop Picture | |
| tomato fruit Search Trop Picture | |
| turmeric root Search Trop Picture | |
| walnut english walnut Search Trop Picture | |
| walnut english walnut nut Search Trop Picture | |
| walnut english walnut oil Search Trop Picture | |
| wheat germ oil Search Trop Picture | |
| wheat oil Search Trop Picture | |
| wheat seed Search Trop Picture |
Synonyms:
| almefrol | |
| aquasol E | |
| 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-, (2S)- |
| denamone | |
| 3,4- | dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol |
| emipherol | |
| endo E | |
| etamican | |
| evitaminum | |
| phytogermine | |
| profecundin | |
| syntopherol | |
| (S)-2,5,7,8- | tetramethyl-2-((4R,8S)-4,8,12-trimethyl-tridecyl)-chroman-6-ol |
| (2S)-2,5,7,8- | tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol |
| (2S)-2,5,7,8- | tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol |
| (+)-a- | tocopherol |
| (+)-alpha- | tocopherol |
| D-a- | tocopherol |
| D-alpha | tocopherol |
| D-alpha- | tocopherol |
| dextro-alpha | tocopherol |
| tokopharm | |
| vascuals | |
| natural | vitamin E |
| natural | vitamin E alcohol 1000iu light USP |
| natural | vitamin E alcohol 1000iu USP |
| vitamin E alpha | |
| vitaplex E |