Articles:
acetophenone, 2'-hydroxy-4'-methoxy- (7CI,8CI)
Notes:
None found
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 552-41-0 2-Hydroxy-4-methoxyacetophenone >98% Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa(moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 uM.
-
-
Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP6253 Paeonol
-
-
O'Laughlin Industries Inc. Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics Leading the Flavor and Fragrance Industry since 1980. O'Laughlin was established in 1980 by its owner and chief executive Michael O'Laughlin, when he moved to Beijing, China and established a small office. Since then it has grown to be a world class producer of chemicals, with significant production facilities in China, and distribution and sales in all major world markets. Email: Sales US Email: John Gick Voice: (852) 2527-1031 Fax: (852) 2529-0231 US Voice: (973) 376-4600 US Fax: (973) 376-4630 Product(s): 774-7136 Paeonol 90
-
-
TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): H0789 2'-Hydroxy-4'-methoxyacetophenone >98.0%(GC)
-
| CAS Number: | 552-41-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 209-012-2 | |
| FDA UNII: | 3R834EPI82 | |
| Nikkaji Web: | J4.483K | |
| Beilstein Number: | 1282794 | |
| MDL: | MFCD00008730 | |
| XlogP3: | 2.00 (est) | |
| Molecular Weight: | 166.17630000 | |
| Formula: | C9 H10 O3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.13100 @ 81.20 °C. |
| Refractive Index: | 1.54320 @ 81.20 °C. |
| Melting Point: | 50.00 to 53.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 301.00 to 302.00 °C. @ 760.00 mm Hg (est) |
| Boiling Point: | 154.00 °C. @ 20.00 mm Hg |
| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. ) |
| logP (o/w): | 1.980 |
| Soluble in: | |
| alcohol | |
| water, 4965 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants skin conditioning |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Paeonol 98% |
| BOC Sciences |
| For experimental / research use only. |
| 2-Hydroxy-4-methoxyacetophenone >98%
Odor: characteristic Use: Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa(moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 uM. |
| Coompo |
| For experimental / research use only. |
| Peonol from Plants ≥96%
Odor: characteristic Use: Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Paeonol also reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats.
It shows antimutagenic activities. It also has anti-inflammatory and analgesic effects in carrageenan-evoked thermal hyperalgesia. Paeonol inhibits anaphylactic reaction by regulating histamine and TNF-a.
It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 µM and 42.5 µM respectively. |
| ExtraSynthese |
| For experimental / research use only. |
| Peonol (HPLC) ≥95% |
| Glentham Life Sciences |
| Paeonol |
| Jalor-Chem |
| For experimental / research use only. |
| 2'-Hydroxy-4'-methoxyacetophenone |
| Kingchem Laboratories |
| 2-Hydroxy-4-methoxyacetophenone |
| O'Laughlin Industries |
| Paeonol 90 |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Paeonol |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| 2'-Hydroxy-4'-methoxyacetophenone 99% |
| TCI AMERICA |
| For experimental / research use only. |
| 2'-Hydroxy-4'-methoxyacetophenone >98.0%(GC) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 490 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 49, Pg. 84, 1953. intravenous-mouse LD50 196 mg/kg BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Yakugaku Zasshi. Journal of Pharmacy. Vol. 89, Pg. 1205, 1969. intraperitoneal-mouse LD50 781 mg/kg BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Yakugaku Zasshi. Journal of Pharmacy. Vol. 89, Pg. 1205, 1969. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | antioxidants | ||
| Recommendation for peonol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for peonol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 11092 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 1-(2-hydroxy-4-methoxyphenyl)ethanone | |
| Chemidplus: | 0000552410 |
| RTECS: | RT1215000 for cas# 552-41-0 |
References:
| 1-(2-hydroxy-4-methoxyphenyl)ethanone | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 11092 |
| Pubchem (sid): | 134978632 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2914.50.5000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| campsis grandiflora flower Search Trop Picture | |
| cynanchum stauntonii root Search Trop Picture | |
| daucus gingidium leaf Search Trop Picture | |
| dioscorea japonica root Search Trop Picture | |
| paeonia montana Search Trop Picture | |
| primula auricula Search Trop Picture |
Synonyms:
| acetophenone, 2'-hydroxy-4'-methoxy- | |
| acetophenone, 2'-hydroxy-4'-methoxy- (7CI,8CI) | |
| 1- | acetyl-2-hydroxy-4-methoxybenzene |
| 2- | acetyl-5-methoxy-phenol |
| ethanone, 1-(2-hydroxy-4-methoxyphenyl)- | |
| 1-[2- | hydroxy-4-(methyloxy)phenyl]ethanone |
| 1-(2- | hydroxy-4-methoxy-phenyl)-ethanone |
| 2- | hydroxy-4-methoxyacetophenone |
| 1-(2- | hydroxy-4-methoxyphenyl) ethanone |
| 1-(2- | hydroxy-4-methoxyphenyl)ethanone |
| 2'- | hydroxy-4'-methoxyacetophenone |
| 4- | methoxy-2-hydroxyacetophenone |
| 4'- | methoxy-2'-hydroxyacetophenone |
| 4-O- | methyl resacetophenone |
| 4-O- | methylresacetophenone |
| paeonol |