zinc orotate
zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-
 
Notes:
None found
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      26-32000 ZINC OROTATE
       
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CAS Number: 68399-76-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 269-988-0
FDA UNII: Z722242H10
MDL: MFCD00167357
Molecular Weight: 375.55942000
Formula: C10 H6 N4 O8 Zn
NMR Predictor: Predict (works with chrome or firefox)
Category: nutrient supplements, EFSA concludes: use is of safety concern.
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -0.928 (est)
Soluble in:
 water, 2.114e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Global Calcium
Zinc Orotate
Penta International
ZINC OROTATE
Santa Cruz Biotechnology
For experimental / research use only.
Orotic acid zinc salt dihydrate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Orotic acid zinc salt dihydrate ≥98.0%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: nutrient supplements, EFSA concludes: use is of safety concern.
Recommendation for zinc orotate usage levels up to:
 not for fragrance use.
 
Recommendation for zinc orotate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Orotic acid salts as sources of orotic acid and various minerals added for nutritional purposes to food supplements
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 68399-76-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 108934
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
Chemidplus: 0068399768
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References:
 zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 108934
Pubchem (sid): 135065433
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 orotic acid zinc salt dihydrate
bis(1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylato-N3,O4)zinc
 zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2)
 zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
 zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-
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Articles:
PubMed: Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells.
PubMed: Ineffectiveness of zinc gluconate nasal spray and zinc orotate lozenges in common-cold treatment: a double-blind, placebo-controlled clinical trial.
PubMed: The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc.
PubMed: Further studies on selective radioprotection by organic zinc salts and synergism of zinc aspartate with WR 2721.
PubMed: Synergism of organic zinc salts and sulfhydryl compounds (thiols) in the protection of mice against acute ethanol toxicity, and protective effects of various metal salts.
PubMed: Some aspects of a non-linear effect of zinc ions on the histamine release from rat peritoneal mast cells.
PubMed: The bioavailability and pharmacokinetics of three zinc salts: zinc pantothenate, zinc sulfate and zinc orotate.
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