disodium phosphate
sodium monohydrogen phosphate (2:1:1)
 
Notes:
Used in foods as a sequestrant, emulsifier, buffering agent, absorbent, pH control agent, protein modifier, source of alkalinity, stabiliser and nutrient supplement Disodium hydrogen phosphate (Na2HPO4) is a sodium salt of phosphoric acid. It is a white powder that is highly hygroscopic and water soluble. It is therefore used commercially as an anti-caking additive in powdered products. It is also known as disodium hydrogen orthophosphate, sodium hydrogen phosphate or sodium phosphate dibasic. It is commercially available in both the hydrated and anhydrous forms.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      DSPA08 DISODIUM PHOSPHATE ANHYDROUS FCC GRANULAR
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      7558-79-4 Disodium hydrogenorthophosphate dibasic, 98%
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      SODIUM PHOSPHATE DIBASIC ACS/USP
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      Products List: View
      Product(s):
      MP-010682 DISODIUM HYDROGENORTHOPHOSPHATE HEPTAHYDRATE PH.
      MP-015883 DISODIUM PHOSPHATE E399 (ii)
      MP-018046 DISODIUM PHOSPHATE
      RE-480141 DI-SODIUM HYDROGEN PHOSPHATE ANHYDROUS RPE-A
       
  • Glentham Life Sciences
Synonyms   Articles   Notes   Search
CAS Number: 7558-79-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 231-448-7
FDA UNII: 22ADO53M6F
MDL: MFCD00003496
Molecular Weight: 141.95807056
Formula: H Na2 O4 P
NMR Predictor: Predict (works with chrome or firefox)
Category: multiple purpose GRAS food substances, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Sodium phosphate dibasic View - review
EU SANCO Sodium phosphates View - review
JECFA Food Additive: Disodium Hydrogen Phosphate
GSFA Codex: Disodium hydrogen phosphate (339(ii))
FEMA Number: 2398 disodium phosphate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):7558-79-4 ; SODIUM PHOSPHATE, DIBASIC
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 135 -- FROZEN DESSERTS
Subpart B--Requirements for Specific Standardized Frozen Desserts
Sec. 135.110 Ice cream and frozen custard.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.305 Enriched farina.


FDA PART 139 -- MACARONI AND NOODLE PRODUCTS
Subpart B--Requirements for Specific Standardized Macaroni and Noodle Products
Sec. 139.110 Macaroni products.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.310 Boiler water additives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.210 Acrylate ester copolymer coating.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS
Subpart B--Specific Prior-Sanctioned Food Ingredients
Sec. 181.29 Stabilizers.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1778 Sodium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart G--Sequestrants1
Sec. 182.6290 Disodium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart G--Sequestrants1
Sec. 182.6778 Sodium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8778 Sodium phosphate.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.85 Caramel.
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 240.00 °C. @ 760.00 mm Hg
Boiling Point: 158.00 °C. @ 760.00 mm Hg (est)
PH Number: 8.90
Vapor Pressure: 1.410000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.9 ( Air = 1 )
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.148 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light. store under nitrogen.
Storage: store under nitrogen.
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
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Organoleptic Properties:
Odor Strength: none
 
Odor Description:
at 100.00 %. 
odorless
Luebke, William tgsc, (2007)
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: anticorrosive agents
buffering agents
fragrance
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Suppliers:
Allan Chemical
Sodium Phosphate Dibasic
American Elements
Sodium Phosphate Dibasic 99%
Odor: characteristic
Use: Sodium Phosphate Dibasic is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
DISODIUM PHOSPHATE ANHYDROUS FCC GRANULAR
BOC Sciences
For experimental / research use only.
Disodium hydrogenorthophosphate dibasic, 98%
Charkit Chemical
SODIUM PHOSPHATE DIBASIC ACS/USP
Dow Chemical
Sodium Phos Dibasic Anhydrous ACS/USP
ECSA Chemicals
DI-SODIUM HYDROGEN PHOSPHATE ANHYDROUS RPE-A
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
DISODIUM HYDROGENORTHOPHOSPHATE HEPTAHYDRATE PH.
ECSA Chemicals
DISODIUM PHOSPHATE E399 (ii)
ECSA Chemicals
DISODIUM PHOSPHATE
Foodchem International
Disodium Phosphate
Glentham Life Sciences
di-Sodium hydrogen phosphate anhydrous, EP, USP grade
Glentham Life Sciences
di-Sodium hydrogen phosphate, anhydrous
Graham Chemical
Disodium Phosphate
Jost Chemical
Sodium Phosphate Dibasic Anhydrous ACS Granular
Jost Chemical
Sodium Phosphate Dibasic Anhydrous USP Granular
Kraft Chemical
Disodium Phosphate
Penta International
SODIUM PHOSPHATE DIBASIC ANHYDROUS POWDER FCC
Penta International
SODIUM PHOSPHATE DIBASIC DRIED POWDER USP/NF
Prinova
Disodium Phosphate Anhydrous
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Phosphate, Dibasic ≥99%
Sigma-Aldrich
Sodium phosphate dibasic, 99%, FG
Certified Food Grade Products
Tianjin Talent Chemical
Disodium Phosphate
Wedor Corporation
DISODIUM PHOSPHATE
Zhong Ya Chemical
Sodium Phosphate, Di
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  17000 mg/kg
Luebke, William tgsc, (2007)

intravenous-rabbit LDLo  1075 mg/kg
BEHAVIORAL: TETANY
Handbuch der Experimentellen Pharmakologie. Vol. 10, Pg. 361, 1950.

oral-rat LD50  17000 mg/kg
"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 16, 1972.

intramuscular-rat LDLo  1000 mg/kg
Biochemische Zeitschrift. Vol. 163, Pg. 226, 1925.

intraperitoneal-rat LDLo  1000 mg/kg
Biochemische Zeitschrift. Vol. 163, Pg. 226, 1925.

Dermal Toxicity:
subcutaneous-rat LDLo 1000 mg/kg
Biochemische Zeitschrift. Vol. 163, Pg. 226, 1925.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: multiple purpose GRAS food substances, acidity regulators
Recommendation for disodium phosphate usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -2300.00000
beverages(nonalcoholic): -350.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -350.00000
fruit ices: -350.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 50.00000250.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the safety evaluation of the active substances, iron, polyethyleneglycol, disodium pyrophosphate, monosodium phosphate and sodium chloride for use in food contact materials
View page or View pdf
Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
Re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 7558-79-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24203
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 3077
WGK Germany: 1
 disodium hydrogen phosphate
Chemidplus: 0007558794
EPA/NOAA CAMEO: hazardous materials
RTECS: 7558-79-4
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References:
 disodium hydrogen phosphate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7558-79-4
Pubchem (cid): 24203
Pubchem (sid): 134986680
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C13558
HMDB (The Human Metabolome Database): Search
FooDB: FDB013359
Export Tariff Code: 2835.22.0000
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•sodium phosphates injection, usp, 3 mm pml (millimolesml)each ml contains 276 mg of monobasic sodium phosphate, monohydrate and 142 mg of dibasic sodium phosphate, anhydrous (equivalent to 268 mg of dibasic sodium phosphate, heptahydrate). it contains no bacteriostat, antimicrobial agent or added buffer. •sodium phosphate preparations: (ahfs, 2009) sodium phosphate preparations: (ahfs, 2009) route dosage form strength brand or generic name (manufacturer) tablet dibasic sodium phosphate (anhydrous) 0.398 g with monobasic sodium phosphate (monohydrate) 1.102 g osmoprep (salix) tablet dibasic sodium phosphate (anhydrous) 0.398 g with monobasic sodium phosphate (monohydrate) 1.102 g visicol (salix) rectal solution dibasic sodium phosphate 60 mgml with monobasic sodium phosphate 160 mgml fleet enema (fleet) rectal solution dibasic sodium phosphate 60 mgml with monobasic sodium phosphate 160 mgml fleet pediatric enema (fleet) •visicol (sodium phosphate monobasic monohydrate, usp, and sodium phosphate dibasic anhydrous, usp)each tablet contains 1.102 grams of sodium phosphate monobasic monohydrate, usp and 0.398 grams of sodium phosphate dibasic anhydrous, usp for a total of 1.5 grams of sodium phosphate per tablet. inert ingredients include microcrystalline cellulose (mcc), nf; magnesium stearate, nf; and colloidal silicon dioxide, nf. visicol is gluten-free. •sodium phosphate and sodium biphosphate enema usp dosage forms-- enema usp: 6% sodium phosphate and 16% sodium biphosphate; sodium phosphate and sodium biphosphate oral solution usp dosage forms-- solution usp: 18% sodium phosphate and 48% sodium biphosphate. •sorensen's phosphate, sorensen's sodium phosphate. disodium phosphate dihydrate •fleet's enema: solution (sodium phosphate 6 g and sodium biphosphate 16 g). fleet's phospho-soda: (sodium phosphate 18 g and sodium biphosphate 48 g). •an oral soln (fleet phospho-soda) contains 1.8 g of dibasic sodium phosphate and 4.8 g of monobasic sodium phosphate in 10 ml saline laxatives •grade: commercial, nf national formulary grade of chemical (sodium phosphate, dibasic anhydrous and heptahydrate), fcc food chemicals codex (sodium phosphate, dibasic anhydrous or dihydrate) •available as anhydrous or dihydric salts.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 anticorrosive agents 
 buffering agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 disodium hydrogen phosphate
 disodium phosphate (food grade)
 disodium phosphate anhydrous
 disodium phosphate anhydrous FCC granular
 phosphoric acid disodium salt
 sodium monohydrogen phosphate (2:1:1)
 sodium phosphate (NaHPO4)
 sodium phosphate dibasic
 sodium phosphate dibasic anhydrous ACS
 sodium phosphate dibasic anhydrous powder FCC
 sodium phosphate dibasic anhydrous ultra pure
 sodium phosphate dibasic anhydrous USP
 sodium phosphate dibasic dried powder USP/NF
 sodium phosphate, di
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