Articles:
| PubMed: | [Comparative determination of podophyllin resin and Podophyllum emodi]. |
podophyllin
Notes:
caustic extract from the roots of podophyllum peltatum and p. emodi. it contains podophyllotoxin and its congeners and is very irritating to mucous membranes and skin. podophyllin is a violent purgative that may cause cns damage and teratogenesis. it is used as a paint for warts, skin neoplasms, and senile keratoses.
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Nanda Medicinal Plants Exports Cultivator & Collector of Himalayan Medicinal Herbs Company working and exporting under CITES Authority. Nanda medicinal plants exports, located at Mansari, (Kullu) H.P. India is a privately owned CITES and APEDA certified supplier of high quality medicinal herbs. The company also enables to cultivate several medicinal herbs in our farms which are of great demand at the local, national and international level. Email: Info US Email: Info Email: Sales US Email: Sales Email: Nanda medicinal plants Voice: +91 98160 57660 Fax: +91 1902 257660 US Voice: +91 98160 57660 US Fax: +91 1902 257660 Nanda medicinal plants +91 1902 257660 Nanda medicinal plants Fax: +91 1902 257660 nmpt2012 
Product(s): Podophyllum Emodi W /p
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 16-59600 PODOPHYLLUM RESIN USP
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| CAS Number: | 9000-55-9 | |
| Other(deleted CASRN): | 8050-60-0 | |
| ECHA EC Number: | 232-546-2 | |
| FDA UNII: | 16902YVY2B | |
| MDL: | MFCD00131926 | |
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Podophyllin from Podophyllum emodii 95% |
| ExtraSynthese |
| For experimental / research use only. |
| Podophyllin |
| Nanda Medicinal Plants |
| Podophyllum Emodi W /p |
| Penta International |
| PODOPHYLLUM RESIN USP |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Podophyllin |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Podophyllin from Podophyllum emodii powder |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
unreported-dog LDLo 120 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. oral-man LDLo 157 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING Southern Medical Journal. Vol. 75, Pg. 1269, 1982. oral-man TDLo 1333 mg/kg BEHAVIORAL: COMA Human Toxicology. Vol. 1, Pg. 373, 1982. oral-mouse LD50 68 mg/kg BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. intraperitoneal-rat LD50 15 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 113, Pg. 124, 1963. parenteral-rat LD50 25 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 84, Pg. 68, 1950. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 58 mg/kg BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. subcutaneous-rat LD50 18 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: EXCITEMENT Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | information only not used for fragrances or flavors | ||
| Recommendation for podophyllum emodi resin usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for podophyllum emodi resin flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| Chemidplus: | 0009000559 |
| RTECS: | TP8925000 for cas# 9000-55-9 |
References:
| Pubchem (sid): | 135356078 |
Other Information:
| MedlinePlusSupp: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| podophyllum emodi Search Trop Picture |
Synonyms:
| podophyllin | |
| podophyllum hexandrum resin | |
| podophyllum resin USP |