choline dihydrogen citrate
2-hydroxy-N,N,N-trimethylethanaminium salt with 2-Hydroxy-1,2,3-propanetricarboxylic acid (1:1)
 
Notes:
None found
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      CDCCIT Choline Citrate
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      77-91-8 Choline Dihydrogen Citrate > 95%
      Choline Dihydrogen Citrate is a highly effective nutritional supplement agents. It can promote fat metabolism and prevent fat accumulation in the liver .
       
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      CHOLINE DIHYDROGEN CITRATE
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      03-23000 CHOLINE DIHYDROGEN CITRATE
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      C0331 Choline Dihydrogen Citrate >99.0%(T)
       
Synonyms   Articles   Notes   Search
CAS Number: 77-91-8Picture of molecule3D/inchi
Other(deleted CASRN): 147584-41-6
ECHA EINECS - REACH Pre-Reg: 201-068-6
FDA UNII: DQ8HHP07GL
MDL: MFCD00038734
Molecular Weight: 295.28897000
Formula: C11 H21 N O8
NMR Predictor: Predict (works with chrome or firefox)
Category: pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 106.00 °C. @ 760.00 mm Hg
Boiling Point: 309.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000057 mmHg @ 25.00 °C. (est)
Flash Point: 311.00 °F. TCC ( 155.20 °C. ) (est)
logP (o/w): -1.721 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
American International Chemical, LLC.
Choline Citrate
BOC Sciences
For experimental / research use only.
Choline Dihydrogen Citrate > 95%
Odor: characteristic
Use: Choline Dihydrogen Citrate is a highly effective nutritional supplement agents. It can promote fat metabolism and prevent fat accumulation in the liver .
Charkit Chemical
CHOLINE DIHYDROGEN CITRATE
Indis NV
For experimental / research use only.
Choline Dihydrogen Citrate
Penta International
CHOLINE DIHYDROGEN CITRATE
Sigma-Aldrich: Aldrich
For experimental / research use only.
Choline dihydrogencitrate salt ≥98%
TCI AMERICA
For experimental / research use only.
Choline Dihydrogen Citrate >99.0%(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

intravenous-mouse LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

oral-mouse LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

intraperitoneal-rat LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

intravenous-rat LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

oral-rat LD50  > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

Dermal Toxicity:
subcutaneous-mouse LD50 > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

subcutaneous-rat LD50 > 4800 mg/kg
Drugs in Japan Vol. 6, Pg. 563, 1982.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: pharmaceuticals / chemical synthisis
Recommendation for choline dihydrogen citrate usage levels up to:
 not for fragrance use.
 
Recommendation for choline dihydrogen citrate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 77-91-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 66170
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate;2-hydroxyethyl(trimethyl)azanium
Chemidplus: 0000077918
RTECS: GA2582000 for cas# 77-91-8
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References:
 2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate;2-hydroxyethyl(trimethyl)azanium
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 66170
Pubchem (sid): 135023860
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
KEGG (GenomeNet): D07691
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2923.10.0000
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate; 2-hydroxyethyl-trimethylazanium
2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate;2-hydroxyethyl(trimethyl)azanium
 cholex
 choline citrate (1:1) (salt)
 choline dihydrogen citrate conditioned
 choline dihydrogen citrate NF 12
 choline dihydrogen citrate NF 12 treated
 choline dihydrogencitrate salt
 choline, citrate (1:1) (salt)
 cholinedihydrogencitratesalt
 cholinvel
 chothyn
 cirrocolina
 citracholin
 citrocholine
 citrocol
 colicitrin
 delichol
 ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxy-1,2,3-propanetricarboxylic acid
2-hydroxy-N,N,N-trimethylethanaminium 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate
2-hydroxy-N,N,N-trimethylethanaminium salt with 2-Hydroxy-1,2,3-propanetricarboxylic acid (1:1)
 neurotropan
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Articles:
PubMed: Temporal B0 field variation effects on MRSI of the human prostate at 7 T and feasibility of correction using an internal field probe.
PubMed: Non-invasive estimation of prostate cancer aggressiveness using diffusion-weighted MRI and 3D proton MR spectroscopy at 3.0 T.
PubMed: Facilitating early recovery of bowel motility after colorectal surgery: a systematic review.
PubMed: Treatment of postoperative ileus with choline citrate--results of a prospective, randomised, placebo-controlled, double-blind multicentre trial.
PubMed: Tumor volume and metabolism of prostate cancer determined by proton magnetic resonance spectroscopic imaging at 3T without endorectal coil reveal potential clinical implications in the context of radiation oncology.
PubMed: The effectiveness of choline citrate infusions monitored by lymphocyte transformation test (LTT) in multiple sclerosis. A new approach to the diagnosis and treatment of the disease.
PubMed: Adult prostate sarcoma: radiological-clinical correlation.
PubMed: Regarding the focal treatment of prostate cancer: inference of the Gleason grade from magnetic resonance spectroscopic imaging.
PubMed: Application of the inverse Monte Carlo treatment planning system IKO for an inhomogeneous dose prescription in the sense of dose painting.
PubMed: Combined use of diffusion-weighted MRI and 1H MR spectroscopy to increase accuracy in prostate cancer detection.
PubMed: A proton NMR study of the effect of a new intravasal injectable male contraceptive RISUG on seminal plasma metabolites.
PubMed: The effects of choline supplementation on physical performance.
PubMed: Quantification by magnetic resonance spectroscopy of metabolites in seminal plasma able to differentiate different forms of azoospermia.
PubMed: Methionine, choline and sulfate interrelationships in the diet of weanling swine.
PubMed: Bioavailability of iron from ferric choline citrate and a ferric copper cobalt choline citrate complex for young pigs.
PubMed: Effect of small intestinal bypass on hepatic lipid accumulation in rats.
PubMed: Chemosensory responses by the heterotrophic marine dinoflagellateCrypthecodinium cohnii.
PubMed: Use of ferric choline citrate in the prevention of iron-deficiency anemia in baby pigs.
PubMed: Hemoglobin synthesis with iron choline citrate in hypochromic anemia of pregnancy.
PubMed: Effect of injected choline citrate in experimental atherosclerosis.
PubMed: [Effect of citrate and choline citrate on anaerobic synthesis of acetylcholine].
PubMed: [The effect of choline citrate on the carbohydrate metabolism].
PubMed: [Results with choline citrate therapy of inoperable cervical carcinoma].
PubMed: NEW and nonofficial remedies: choline dihydrogen citrate.
PubMed: [Choline citrate].
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